Abstract: The present invention relates to bispecific antibodies against ROR1 and CD3, their manufacture and use.

Abstract: The present invention relates to bispecific HER2 antibodies, novel HER2 antibody variants, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.

Abstract: The invention relates to new antibodies against BCMA, their manufacture and use.

Abstract: The invention relates to novel bispecific antigen binding molecules, comprising (a) four moieties capable of specific binding to a costimulatory TNF receptor family member, (b) at least one moiety capable of specific binding to a target cell antigen, and (c) a Fc domain composed of a first and second subunit capable of stable association, and to methods of producing these molecules and to methods of using the same.

Abstract: Method for regulating a bank of alternators comprising at least two alternators that deliver their output in parallel to a load (C), said alternators each being provided with a regulator (12, 13) that is configured to deliver an output signal representative of the reactive power level of the corresponding alternator divided by its nominal reactive power, and a control law allowing the reactive power level of the alternator to be modified depending on an input signal, method wherein a weighted signal employed as the input signal of these regulators is generated from the output signals representative of the reactive power level of each of the alternators, i.e. the signals delivered by the corresponding regulators, so as to make each of the alternators converge to a predefined reactive power level (Trp).

Abstract: An electronic device, in particular an alternator regulator, comprising a power stage to be connected to an inductive load, in particular to an alternator inductor, comprising at least one first pair of power transistors connected to a terminal of a DC bus, and a control circuit for said transistors, the transistors being disposed in parallel between said terminal of the DC bus and a first output to be connected to the load, at least one flyback diode connecting the opposite terminal of the DC bus to the first output, the control circuit being designed to generate a pulsed control signal for regulating the current in the load and for detecting a failure of one of the transistors, the control circuit being designed, during normal operation, to send the control signal to one of the transistors of the first pair, while maintaining the other transistor of said pair in an off-state.

Abstract: Method for regulating a bank of alternators comprising at least two alternators that deliver their output in parallel to a load (C), said alternators each being provided with a regulator (12, 13) that is configured to deliver an output signal representative of the reactive power level of the corresponding alternator divided by its nominal reactive power, and a control law allowing the reactive power level of the alternator to be modified depending on an input signal, method wherein a weighted signal employed as the input signal of these regulators is generated from the output signals representative of the reactive power level of each of the alternators, i.e. the signals delivered by the corresponding regulators, so as to make each of the alternators converge to a predefined reactive power level (Trp).

Abstract: An antibody specifically binding to human BCMA, characterized in that the binding of said antibody is not reduced by APRIL and not reduced by BAFF, said antibody does not alter APRIL-dependent NF-?B activation, BAFF-dependent NF-?B activation, and does not alter NF-?B activation without BAFF and APRIL is useful as a therapeutic agent.

Abstract: An antibody specifically binding to human BCMA, characterized in that the binding of said antibody is not reduced by APRIL and not reduced by BAFF, said antibody does not alter APRIL-dependent NF-?B activation, BAFF-dependent NF-?B activation, and does not alter NF-?B activation without BAFF and APRIL is useful as a therapeutic agent.

Abstract: The present invention relates to bispecific HER2 antibodies, novel HER2 antibody variants, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.

Abstract: The invention relates to new antibodies against BCMA, their manufacture and use.

Abstract: A bispecific antibody specifically binding to the two targets human CD3? (further named also as “CD3”) and the extracellular domain of human ROR1 (further named also as “ROR1”), characterized in that the bispecific antibody does not internalize in a cell based assay at 37° C. during 2 hrs, using ROR1-positive B-CLL cells and used at an antibody concentration of 1 nM, whereby not internalize means, that the mean fluorescence intensity (MFI), as detected by flow cytometry, of a bispecific antibody upon binding to ROR1-positive primary B-CLL cells measured at time 0 is not reduced for more than 50%, preferably not more than 30% when re-measured after a 2 hr-incubation at 37° C. and which is useful for the treatment of B-cell malignancies like Chronic Lymphocytic Leukemia or B-cell disorders expressing ROR1 and ROR1-positive solid tumors.

Abstract: The invention relates to new antibodies against BCMA, their manufacture and use.

Abstract: An electronic apparatus for a rotating electric machine, notably an alternator voltage regulator or speed variator, including an electronic circuit and a wired bus allowing the exchange of information with the outside, such that the bus is defined by an interface module rigidly fixed to a board of the electronic circuit and communicating via a wireless link with the latter.

Abstract: The present invention relates to bispecific HER2 antibodies, novel HER2 antibody variants, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.

Abstract: An electronic device, in particular a variable speed drive or alternator regulator, comprising a heat sink (10) and a power card comprising a printed circuit board, housed in a casing, characterized in that it comprises a part (100) attached, on the one hand, to the heat sink (10) and attached, on the other hand, to the board and coming into contact with at least one conductive track of the power card, so as to provide an electrical contact between the heat sink and said track, said part (100) having a face that is accessible from the outside of the device for attaching a lug connected to a ground and/or an earth cable.

Abstract: An assembly comprising: an electronic device (1), in particular a variable speed drive or alternator regulator, comprising a casing, the rear of which is equipped with a heat sink (10), produced from a metal profile section, for cooling at least one power component; a first assembly of elements (20) for attaching the device on a support, each comprising at least one tab to be engaged in the profile section by sliding it therein, and an attachment lug provided with at least one screw through-hole; a second assembly of elements for attaching the device on a support, each comprising at least one tab to be engaged in the profile section by sliding it therein, and an attachment lug provided with at least one screw through-hole, the elements being of different shapes.

Abstract: An electronic device, in particular an alternator regulator, comprising a power stage to be connected to an inductive load, in particular to an alternator inductor, comprising at least one first pair of power transistors connected to a terminal of a DC bus, and a control circuit for said transistors, the transistors being disposed in parallel between said terminal of the DC bus and a first output to be connected to the load, at least one flyback diode connecting the opposite terminal of the DC bus to the first output, the control circuit being designed to generate a pulsed control signal for regulating the current in the load and for detecting a failure of one of the transistors, the control circuit being designed, during normal operation, to send the control signal to one of the transistors of the first pair, while maintaining the other transistor of said pair in an off-state.

Abstract: An electronic device (1), in particular a variable speed drive or alternator regulator, comprising at least one power component mounted on a heat sink (10) and a plurality of capacitors extending through at least one opening of the heat sink, characterized in that it comprises a recess, which accommodates a sheet seal that is applied, on the one hand, on an internal face of the heat sink and, on the other hand, on an internal face facing a casing fitted onto the heat sink, with the internal faces of the heat sink and of the casing coming into contact.

Abstract: The invention relates to new antibodies against BCMA, their manufacture and use.