Patents by Inventor Samuel O. Nortey

Samuel O. Nortey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ISOXAZOLINE ALPHA 1a/1d ADRENORECEPTOR ANTAGONISTS
    Publication number: 20080221116
    Abstract: The present invention relates to isoxazolines useful as selective ?1a/?1d adrenoreceptor antagonists for the treatment of benign prostatic hypertrophy and/or lower urinary tract symptoms as well as to pharmaceutical compositions comprising said compounds, processes to prepare these compounds, and the use of these compounds as ?1a/?1d adrenoreceptor modulators in a method of treatment.
    Type: Application
    Filed: September 14, 2007
    Publication date: September 11, 2008
    Inventors: Ellen W. Baxter, Samuel O. Nortey, Allen B. Reitz
  • Benzamidine derivatives
    Patent number: 6887876
    Abstract: Benzamidine derivatives are useful delta-opioid receptor modulators, agonists useful as analgesics and antagonists useful as immunosuppressants, antiinflammatory agents, agents for the treatment of neurological and psychiatric conditions, medicaments for drug and alcohol abuse, agents for treating gastritis and diarrhea, cardiovascular agents and agents for the treatment of respiratory diseases.
    Type: Grant
    Filed: December 11, 2001
    Date of Patent: May 3, 2005
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Ellen W. Baxter, Samuel O. Nortey, Allen B. Reitz
  • Benzamidine derivatives
    Publication number: 20020123489
    Abstract: Benzamidine derivatives are useful delta-opioid receptor modulators, agonists useful as analgesics and antagonists useful as immunosuppressants, antiinflammatory agents, agents for the treatment of neurological and psychiatric conditions, medicaments for drug and alcohol abuse, agents for treating gastritis and diarrhea, cardiovascular agents and agents for the treatment of respiratory diseases.
    Type: Application
    Filed: December 11, 2001
    Publication date: September 5, 2002
    Inventors: Ellen W. Baxter, Samuel O. Nortey, Allen B. Reitz
  • C-6 ring-substituted pyrido[1,2-a]benzimidazole derivatives useful in treating central nervous system disorders
    Patent number: 6358946
    Abstract: A C-6 ring-substituted pyrido[1,2-a]benzimidazole derivative of the formula: methods of preparation and pharmaceutical compositions containing a substituted pyrido[1,2-a]benzimidzole derivative as the active ingredient are disclosed. The substituted pyrido[1,2-a]benzimidazole derivatives are useful in the treatment of central nervous system disorders.
    Type: Grant
    Filed: July 20, 2000
    Date of Patent: March 19, 2002
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Allen B. Reitz, Samuel O. Nortey, Pauline Sanfilippo, Malcolm K. Scott
  • Heterocyclic derivatives useful in treating central nervous system disorders
    Patent number: 5968946
    Abstract: This invention relates to a series of substituted 3-oxo-pyrrolo[1,2-a]imidazopyridine derivatives of the formula 1 ##STR1## where X.sub.1 -X.sub.4, R.sub.1, R.sub.2 and Ar are defined herein. In addition the invention relates to pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are ligands for the benzodiazepine site on the GABA-A receptor and display anxiolytic and anticonvulsant activity in animal models.
    Type: Grant
    Filed: October 5, 1998
    Date of Patent: October 19, 1999
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Bruce E. Maryanoff, David McComsey, James J. McNally, Samuel O. Nortey, Allen B. Reitz
  • 2-oxo-pyrrolo[1,2-A]benzimidazole-3-carboxyl derivatives useful in treating central nervous system disorders
    Patent number: 5521200
    Abstract: A compound of the general formula I; ##STR1## is disclosed as useful in treating disorders of the central nervous system. Pharmaceutical compositions and methods of treatment are also disclosed.
    Type: Grant
    Filed: November 1, 1994
    Date of Patent: May 28, 1996
    Inventors: Winston Ho, Bruce E. Maryanoff, David F. McComsey, Samuel O. Nortey
  • Anticonvulsant pseudofructopyranose sulfamates
    Patent number: 5498629
    Abstract: A compound of the general formula I: ##STR1## is disclosed as a potent anticonvulsant drug. Pharmaceutical compositions and methods of treatment are also disclosed.
    Type: Grant
    Filed: November 10, 1994
    Date of Patent: March 12, 1996
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Michael J. Costenzo, Bruce E. Maryanoff, David F. McComsey, Samuel O. Nortey
  • Anticonvulsant phenethyl sulfamates
    Patent number: 4792569
    Abstract: Sulfamates of the following formula (I) are anticonvulsants and are useful in the treatment of epilepsy: ##STR1## wherein R is one or more substituents such as alkyl, halo, alkoxy, CH.sub.3 or nitro; andx is 0-3.
    Type: Grant
    Filed: August 27, 1987
    Date of Patent: December 20, 1988
    Assignee: McNeilab, Inc.
    Inventors: Bruce E. Maryanoff, Samuel O. Nortey
  • Anticonvulsant dioxolane methane sulfamates
    Patent number: 4591601
    Abstract: Sulfamates of the following formula (I): ##STR1## wherein R.sup.1 and R.sup.2 are as herein defined have been found to exhibit anticonvulsant activity and are thus useful in the treatment of conditions such as epilepsy. Further, pharmaceutical compositions containing a compound of formula (I) as well as methods for their use and intermediates form part of the present invention.
    Type: Grant
    Filed: April 12, 1985
    Date of Patent: May 27, 1986
    Assignee: McNeilab, Inc.
    Inventors: Bruce E. Maryanoff, Samuel O. Nortey