Abstract: A functional safety system performs safety analysis on three-dimensional point cloud data measured by a time-of-flight (TOF) sensor that monitors a hazardous industrial area that includes an automation system. To reduce the amount of point cloud data to be analyzed for hazardous conditions, the safety system executes a real-time emulation of the automation system using a digital twin and live controller data read from an industrial controller that monitors and controls the automation system. The safety system generates simulated, or shadow, point cloud data based on the emulation and subtracts this simulate point cloud data from the measured point cloud data received from the TOF sensor. This removes portions of the point cloud data corresponding to known or expected elements within the monitored area. Any remaining entities detected in the reduced point cloud data can be further analyzed for safety concerns.

Abstract: A functional safety system performs safety analysis on three-dimensional point cloud data measured by a time-of-flight (TOF) sensor that monitors a hazardous industrial area that includes an automation system. To reduce the amount of point cloud data to be analyzed for hazardous conditions, the safety system executes a real-time emulation of the automation system using a digital twin and live controller data read from an industrial controller that monitors and controls the automation system. The safety system generates simulated, or shadow, point cloud data based on the emulation and subtracts this simulate point cloud data from the measured point cloud data received from the TOF sensor. This removes portions of the point cloud data corresponding to known or expected elements within the monitored area. Any remaining entities detected in the reduced point cloud data can be further analyzed for safety concerns.

Abstract: Apparatus and methods are described herein that provide a vibratory device that can apply a vibratory signal to a portion of a head of a user such that the vibratory signal can be conducted via bone to a vestibular system of the user and cause a portion of the vestibular system to move in a manner equivalent to that of a therapeutically effective vibratory signal applied to an area overlaying a mastoid bone of the user. The vibratory device can be associated with frequencies less than 200 Hz. The vibratory device can be effective at treating a physiological condition associated with the vestibular system.

Abstract: Apparatus and methods are described herein that provide a vibratory device that can apply a vibratory signal to a portion of a head of a user such that the vibratory signal can be conducted via bone to a vestibular system of the user and cause a portion of the vestibular system to move in a manner equivalent to that of a therapeutically effective vibratory signal applied to an area overlaying a mastoid bone of the user. The vibratory device can be associated with frequencies less than 200 Hz. The vibratory device can be effective at treating a physiological condition associated with the vestibular system.

Abstract: A spark plug, including a metallic shell, an insulator, a center electrode, and a ground electrode. The insulator includes a first outer surface at least partly along an exposed portion and a second outer surface at least partly along an unexposed portion. The first outer surface extends between the exposed-unexposed interface to a tip merge portion adjacent a distal end of the insulator. The first outer surface and the second outer surface meet at a nose surface transition. At the nose surface transition, the first outer surface is disposed at a first angle with respect to a central axis of the spark plug, and the second outer surface is disposed at a second angle with respect to the central axis of the spark plug. The first angle is larger than the second angle, and the nose surface transition is located within the unexposed portion or at the exposed-unexposed interface.

Abstract: Apparatus and methods are described herein that provide a vibratory device that can apply a vibratory signal to a portion of a head of a user such that the vibratory signal can be conducted via bone to a vestibular system of the user and cause a portion of the vestibular system to move in a manner equivalent to that of a therapeutically effective vibratory signal applied to an area overlaying a mastoid bone of the user. The vibratory device can be associated with frequencies less than 200 Hz. The vibratory device can be effective at treating a physiological condition associated with the vestibular system.

Abstract: A spark plug, including a metallic shell, an insulator, a center electrode, and a ground electrode. The insulator includes a first outer surface at least partly along an exposed portion and a second outer surface at least partly along an unexposed portion. The first outer surface extends between the exposed-unexposed interface to a tip merge portion adjacent a distal end of the insulator. The first outer surface and the second outer surface meet at a nose surface transition. At the nose surface transition, the first outer surface is disposed at a first angle with respect to a central axis of the spark plug, and the second outer surface is disposed at a second angle with respect to the central axis of the spark plug. The first angle is larger than the second angle, and the nose surface transition is located within the unexposed portion or at the exposed-unexposed interface.

Abstract: Apparatus and methods are described herein that provide a vibratory device that can apply a vibratory signal to a portion of a head of a user such that the vibratory signal can be conducted via bone to a vestibular system of the user and cause a portion of the vestibular system to move in a manner equivalent to that of a therapeutically effective vibratory signal applied to an area overlaying a mastoid bone of the user. The vibratory device can be associated with frequencies less than 200 Hz. The vibratory device can be effective at treating a physiological condition associated with the vestibular system.

Abstract: Apparatus and methods are described herein that provide a vibratory device that can apply a vibratory signal to a portion of a head of a user such that the vibratory signal can be conducted via bone to a vestibular system of the user and cause a portion of the vestibular system to move in a manner equivalent to that of a therapeutically effective vibratory signal applied to an area overlaying a mastoid bone of the user. The vibratory device can be associated with frequencies less than 200 Hz. The vibratory device can be effective at treating a physiological condition associated with the vestibular system.

Abstract: Apparatus and methods are described herein that provide a vibratory device that can apply a vibratory signal to a portion of a head of a user such that the vibratory signal can be conducted via bone to a vestibular system of the user and cause a portion of the vestibular system to move in a manner equivalent to that of a therapeutically effective vibratory signal applied to an area overlaying a mastoid bone of the user. The vibratory device can be associated with frequencies less than 200 Hz. The vibratory device can be effective at treating a physiological condition associated with the vestibular system.

Abstract: Particular vibratory signals are delivered to the vestibular system in order to reduce or prevent symptoms of maladies of the vestibular system.

Abstract: A conditioning process and equipment are provided for removing hardness from water circulated in a system. A sidestream from such system is routed to a reaction chamber and back to the system. A conditioner is added to the sidestream water and in some embodiments is routed through a sidestream inlet from the top of the reaction chamber to its lower portion in a swirling motion. A buffer is added to the sidestream exiting the reaction chamber, and in some embodiments is added upstream of a pH sensor. In some embodiments a polymer is added. A fluid bed develops in the reaction chamber consisting of conditioner, buffer, precipitated solids and sidestream water. An upper outlet on the reaction chamber regulates the height of the fluid bed, and a drain provides for periodic discharge of the lower fluid bed. In some embodiments, a corrosion inhibitor blend is pre-mixed with the buffer.

Abstract: The invention generally relates to hapten compounds comprising either (+) methamphetamine or (+) amphetamine conjugated to a linker. Generally speaking, hapten compounds of the invention may be used to elicit an immune response to one or more of (+) methamphetamine, (+) amphetamine, or (+) MDMA.

Abstract: A conditioning process and equipment are provided for removing hardness from water circulated in a system, such as an evaporative cooling system. A sidestream from such system is routed to a reaction chamber and back to the system. A conditioner is added to the sidestream water and in some embodiments is routed through a sidestream inlet from the top of the reaction chamber to its lower portion. A buffer is added to the sidestream exiting the reaction chamber, and in some embodiments is added upstream of a pH sensor. A fluid bed develops in the reaction chamber consisting of conditioner, buffer, precipitated solids and sidestream water. An upper outlet on the reaction chamber regulates the height of the fluid bed, and a drain provides for periodic discharge of the lower fluid bed. In another embodiment, a corrosion inhibitor blend is pre-mixed with the buffer.

Abstract: A conditioning process and equipment are provided for removing hardness from water circulated in a system, such as an evaporative cooling system. A sidestream from such system is routed to a reaction chamber and back to the system. A conditioner is added to the sidestream before entering the reaction chamber and a buffer is added to the sidestream exiting the reaction chamber. Since some of the buffered sidestream is re-circulated, a fluid bed develops in the reaction chamber consisting of conditioner, buffer, precipitated solids and sidestream water. Continued sidestream water entry mixes with the fluid bed causing additional precipitation of solids. An upper outlet on the reaction chamber regulates the height of the fluid bed, and a drain provides for periodic discharge of the lower fluid bed. In another embodiment, a corrosion inhibitor blend is pre-mixed with the buffer, resulting in a softer, more readily drainable fluid bed.

Abstract: The present invention is related to antibodies directed to various drugs of abuse and uses of such antibodies. In preferred embodiments, the drugs of abuse are amphetamine, methamphetamine, or phencyclidine (PCP). In particular, in accordance with the present invention, there are provided fully man monoclonal antibodies directed to drugs of abuse. Nucelotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR3 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.