Patents by Inventor Samuel Pleasure

Samuel Pleasure has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of pure cultures of post-mitotic human neurons
    Patent number: 5654189
    Abstract: NTera 2/cl.D1 (NT2) cells, a human teratocarcinoma cell line, were manipulated following retinoic acid (RA) treatment to yield >95% pure cultures of neuronal cells (NT2-N cells). This culture method is capable of yielding sufficient highly differentiated post-mitotic NT2-N cells for both biochemical and molecular biological studies. NT2 cells can be transfected efficiently and the transfected gene products can be expressed in both NT2 and NT2-N cells.
    Type: Grant
    Filed: June 10, 1996
    Date of Patent: August 5, 1997
    Assignee: Trustees of the University of Pennsylvania
    Inventors: Virginia Lee, Samuel Pleasure
  • Preparation of pure cultures of post-mitotic human neurons
    Patent number: 5175103
    Abstract: NTera 2/cl.D1 (NT2) cells, a human teratocarcinoma cell line, were manipulated following retinoic acid (RA) treatment to yield>95% pure cultures of neuronal cells (NT2-N cells). This culture method is capable of yielding sufficient highly differentiated post-mitotic NT2-N cells for both biochemical and molecular biological studies. NT2 cells can be transfected efficiently and the transfected gene products can be expressed in both NT2 and NT2-N cells.
    Type: Grant
    Filed: October 21, 1991
    Date of Patent: December 29, 1992
    Assignee: Trustees of University of Pennsylvania
    Inventors: Virginia Lee, Samuel Pleasure