Patents by Inventor Samuel Shaolian

Samuel Shaolian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190000620
    Abstract: Systems and methods treat a heart valve using a magnetically adjustable annuloplasty ring attached to or near a cardiac valve annulus. A changing magnetic field may be used to selectively increase or decrease a circumference of, or otherwise modify the shape of, the implanted annuloplasty ring. The adjustable annuloplasty ring includes a tubular body member, one or more adjustable members, and an internal magnet within the tubular body member. The tubular body member and the one or more adjustable members form a ring shape. The internal magnet is configured to rotate in response to a rotating external magnetic field. The internal magnet is coupled to the one or more adjustable members to change a dimension of the ring shape as the internal magnet rotates. A system for treating a heart valve may include an external adjustment device having one or more external magnets to generate the rotating external magnetic field.
    Type: Application
    Filed: August 14, 2018
    Publication date: January 3, 2019
    Inventors: Samuel Shaolian, Scott Pool, Ross Tsukashima, Daniel Anderson
  • Patent number: 10076413
    Abstract: Systems and methods treat a heart valve using a magnetically adjustable annuloplasty ring attached to or near a cardiac valve annulus. A changing magnetic field may be used to selectively increase or decrease a circumference of, or otherwise modify the shape of, the implanted annuloplasty ring. The adjustable annuloplasty ring includes a tubular body member, one or more adjustable members, and an internal magnet within the tubular body member. The tubular body member and the one or more adjustable members form a ring shape. The internal magnet is configured to rotate in response to a rotating external magnetic field. The internal magnet is coupled to the one or more adjustable members to change a dimension of the ring shape as the internal magnet rotates. A system for treating a heart valve may include an external adjustment device having one or more external magnets to generate the rotating external magnetic field.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: September 18, 2018
    Assignee: NuVasive Specialized Orthopedics, Inc.
    Inventors: Samuel Shaolian, Scott Pool, Ross Tsukashima, Daniel Anderson
  • Publication number: 20160143734
    Abstract: Systems and methods treat a heart valve using a magnetically adjustable annuloplasty ring attached to or near a cardiac valve annulus. A changing magnetic field may be used to selectively increase or decrease a circumference of, or otherwise modify the shape of, the implanted annuloplasty ring. The adjustable annuloplasty ring includes a tubular body member, one or more adjustable members, and an internal magnet within the tubular body member. The tubular body member and the one or more adjustable members form a ring shape. The internal magnet is configured to rotate in response to a rotating external magnetic field. The internal magnet is coupled to the one or more adjustable members to change a dimension of the ring shape as the internal magnet rotates. A system for treating a heart valve may include an external adjustment device having one or more external magnets to generate the rotating external magnetic field.
    Type: Application
    Filed: October 16, 2015
    Publication date: May 26, 2016
    Inventors: Samuel Shaolian, Scott Pool, Ross Tsukashima, Daniel Anderson
  • Publication number: 20160007896
    Abstract: The invention relates generally to in vivo collection of circulating molecules, tumor cells and other biological markers using a collecting probe. The probe is configured for placement within a living organism for an extended period of time to provide sufficient yield of biological marker for analysis.
    Type: Application
    Filed: September 23, 2015
    Publication date: January 14, 2016
    Inventors: David Hoon, Bret Taback, Samuel Shaolian
  • Patent number: 9162884
    Abstract: The invention relates generally to in vivo collection of circulating molecules, tumor cells and other biological markers using a collecting probe. The probe is configured for placement within a living organism for an extended period of time to provide sufficient yield of biological marker for analysis.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: October 20, 2015
    Assignee: John Wayne Cancer Institute
    Inventors: David Hoon, Bret Taback, Samuel Shaolian
  • Publication number: 20140206961
    Abstract: The invention relates generally to in vivo collection of circulating molecules, tumor cells and other biological markers using a collecting probe. The probe is configured for placement within a living organism for an extended period of time to provide sufficient yield of biological marker for analysis. In some embodiments of the invention, active attraction of biological markers are provided. A partial or complete analytic/detection assembly may also be integrated with the probe.
    Type: Application
    Filed: October 28, 2013
    Publication date: July 24, 2014
    Applicant: John Wayne Cancer Institute
    Inventors: David Hoon, Bret Taback, Samuel Shaolian
  • Publication number: 20140018910
    Abstract: A prosthetic implant for treating a diseased aortic valve is described. The prosthetic implant includes a substantially tubular body configured to be positioned in an aorta of a patient, at or near the patient's aortic valve. The body includes a lumen extending through the body; and an adjustable frame surrounding the lumen. The prosthetic implant further includes at least one adjustable element located in or on the body and extending at least partially around a circumference of the lumen. The at least one adjustable element is transformable, in response to application of an activation energy, from a first configuration to a second configuration. The at least one adjustable element may engage at least one of a root of the aorta, an annulus of the aortic valve, and the patient's left ventricle, when the at least one adjustable element is in the second configuration.
    Type: Application
    Filed: May 24, 2013
    Publication date: January 16, 2014
    Applicant: MICARDIA CORPORATION
    Inventors: Shawn Moaddeb, Samuel Shaolian, Emanuel Shaoulian, Jay A. Lenker
  • Patent number: 8569044
    Abstract: The invention relates generally to in vivo collection of circulating molecules, tumor cells and other biological markers using a collecting probe. The probe is configured for placement within a living organism for an extended period of time to provide sufficient yield of biological marker for analysis. In some embodiments of the invention, active attraction of biological markers are provided. A partial or complete analytic/detection assembly may also be integrated with the probe.
    Type: Grant
    Filed: August 8, 2011
    Date of Patent: October 29, 2013
    Assignee: John Wayne Cancer Institute
    Inventors: David Hoon, Bret Taback, Samuel Shaolian
  • Patent number: 8449604
    Abstract: A prosthetic implant for treating a diseased aortic valve is described. The prosthetic implant includes a substantially tubular body configured to be positioned in an aorta of a patient, at or near the patient's aortic valve. The body includes a lumen extending through the body from a proximal end to a distal end of the body; and an adjustable frame surrounding the lumen. The prosthetic implant further includes at least one adjustable element located in or on the body and extending at least partially around a circumference of the lumen. The at least one adjustable element includes a shape memory material and is transformable, in response to application of an activation energy, from a first configuration to a second configuration, wherein the first configuration and second configuration differ in a size of at least one dimension of the at least one adjustable element.
    Type: Grant
    Filed: August 19, 2009
    Date of Patent: May 28, 2013
    Assignee: MiCardia Corporation
    Inventors: Shawn Moaddeb, Samuel Shaolian, Emanuel Shaoulian, Jay A. Lenker
  • Publication number: 20120221101
    Abstract: An adjustable annuloplasty device is described. The device includes a body member comprising a shape memory material, the body member configured to be placed at or near a base of a valve of a heart. The device further includes a hysteretic material configured to undergo magnetic hysteresis in response to a first activation energy, the hysteretic material being in thermal communication with the shape memory material. The body member may have a first size of a body member dimension in a first configuration and a second size of the body member dimension in a second configuration. When the body member is in position in the heart, a change from the first configuration to the second configuration changes a size of a dimension of the annulus of the valve.
    Type: Application
    Filed: February 24, 2012
    Publication date: August 30, 2012
    Applicant: MICARDIA CORPORATION
    Inventors: Shawn Moaddeb, Samuel Shaolian, James Huntington Dabney, Conrad Sawicz, Jay A. Lenker
  • Publication number: 20120191009
    Abstract: The invention relates generally to in vivo collection of circulating molecules, tumor cells and other biological markers using a collecting probe. The probe is configured for placement within a living organism for an extended period of time to provide sufficient yield of biological marker for analysis.
    Type: Application
    Filed: December 21, 2011
    Publication date: July 26, 2012
    Inventors: David Hoon, Bret Taback, Samuel Shaolian
  • Publication number: 20120136433
    Abstract: An intraoperative adjustment device is described. In some embodiments, the device includes an elongate body including a proximal end and a distal end, the distal end configured to penetrate an outer surface of an adjustable cardiac implant implanted in a patient's heart, and the proximal end and the distal end connected by at least one energy-transfer member. In some embodiments, the distal end includes at least one electrode coupled to the energy-transfer member and configured to deliver an activation energy to the adjustable cardiac implant. In some embodiments, the proximal end is configured to attach to an energy source that provides the activation energy. In some embodiments, the proximal end is configured to be located outside the patient's body while the distal end is coupled to the adjustable cardiac implant that is implanted in the patient's heart.
    Type: Application
    Filed: June 29, 2011
    Publication date: May 31, 2012
    Applicant: MICARDIA CORPORATION
    Inventors: Alexander MARMUREANU, Le LE, Jesus FLORES, Jason TRAN, Samuel SHAOLIAN
  • Publication number: 20120035499
    Abstract: The invention relates generally to in vivo collection of circulating molecules, tumor cells and other biological markers using a collecting probe. The probe is configured for placement within a living organism for an extended period of time to provide sufficient yield of biological marker for analysis. In some embodiments of the invention, active attraction of biological markers are provided. A partial or complete analytic/detection assembly may also be integrated with the probe.
    Type: Application
    Filed: August 8, 2011
    Publication date: February 9, 2012
    Inventors: DAVID HOON, BRET TABACK, SAMUEL SHAOLIAN
  • Patent number: 8084246
    Abstract: The invention relates generally to in vivo collection of circulating molecules, tumor cells and other biological markers using a collecting probe. The probe is configured for placement within a living organism for an extended period of time to provide sufficient yield of biological marker for analysis.
    Type: Grant
    Filed: April 24, 2008
    Date of Patent: December 27, 2011
    Assignee: John Wayne Cancer Institute
    Inventors: David Hoon, Bret Taback, Samuel Shaolian
  • Publication number: 20110230962
    Abstract: Embodiments of a dynamically adjustable artificial chordae tendinae implant are described. In some embodiments the implant includes a body portion, including an adjustable portion. In some embodiments, the implant includes a plurality of adjustable portions. In some embodiments the adjustable element can include a shape memory material. The adjustable portion can be configured to transform from a first conformation to a second conformation in response to an activation energy. In some embodiments, the activation energy can be one of electromagnetic energy, acoustic energy, light energy, thermal energy, electrical energy, mechanical energy, or a combination of energies. The implant couples a heart valve leaflet to a papillary muscle. Activation of the shape memory material regulates tension between the muscle and valve leaflet improving coaptation of heart valve leaflets, and reducing or eliminating regurgitation.
    Type: Application
    Filed: November 8, 2010
    Publication date: September 22, 2011
    Applicant: MICARDIA CORPORATION
    Inventors: Shahram Moaddeb, Samuel Shaolian
  • Patent number: 7993909
    Abstract: The invention relates generally to in vivo collection of circulating molecules, tumor cells and other biological markers using a collecting probe. The probe is configured for placement within a living organism for an extended period of time to provide sufficient yield of biological marker for analysis. In some embodiments of the invention, active attraction of biological markers are provided. A partial or complete analytic/detection assembly may also be integrated with the probe.
    Type: Grant
    Filed: September 11, 2008
    Date of Patent: August 9, 2011
    Assignee: John Wayne Cancer Institute
    Inventors: David Hoon, Bret Taback, Samuel Shaolian
  • Publication number: 20100185274
    Abstract: A prosthetic implant for treating a diseased aortic valve is described. The prosthetic implant includes a substantially tubular body configured to be positioned in an aorta of a patient, at or near the patient's aortic valve. The body includes a lumen extending through the body from a proximal end to a distal end of the body; and an adjustable frame surrounding the lumen. The prosthetic implant further includes at least one adjustable element located in or on the body and extending at least partially around a circumference of the lumen. The at least one adjustable element includes a shape memory material and is transformable, in response to application of an activation energy, from a first configuration to a second configuration, wherein the first configuration and second configuration differ in a size of at least one dimension of the at least one adjustable element.
    Type: Application
    Filed: August 19, 2009
    Publication date: July 22, 2010
    Applicant: Micardia Corporation
    Inventors: Shawn Moaddeb, Samuel Shaolian, Emanuel Shaoulian, Jay A. Lenker
  • Patent number: 7553625
    Abstract: The invention relates generally to in vivo collection of circulating molecules, tumor cells and other biological markers using a collecting probe. The probe is configured for placement within a living organism for an extended period of time to provide sufficient yield of biological marker for analysis. In some embodiments of the invention, active attraction of biological markers are provided. A partial or complete analytic/detection assembly may also be integrated with the probe.
    Type: Grant
    Filed: August 27, 2004
    Date of Patent: June 30, 2009
    Assignee: John Wayne Cancer Institute
    Inventors: David Hoon, Bret Taback, Samuel Shaolian
  • Patent number: 7536228
    Abstract: An activation device for applying energy to an implanted annuloplasty ring is described. In some embodiments, the activation device includes an outer elongate member having an outer elongate member distal end and an outer elongate member proximal end, and a lumen therebetween. In some embodiments, the activation device further includes an inner elongate member having a inner elongate member distal end and a inner elongate member proximal end, and a lumen therebetween, wherein the inner elongate member is slidably insertable through the lumen of the outer elongate member.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: May 19, 2009
    Assignee: MiCardia Corporation
    Inventors: Samuel Shaolian, Shahram Moaddeb, Maurice Buchbinder, David Zarbatany, Jason Tran
  • Publication number: 20090011445
    Abstract: The invention relates generally to in vivo collection of circulating molecules, tumor cells and other biological markers using a collecting probe. The probe is configured for placement within a living organism for an extended period of time to provide sufficient yield of biological marker for analysis. In some embodiments of the invention, active attraction of biological markers are provided. A partial or complete analytic/detection assembly may also be integrated with the probe.
    Type: Application
    Filed: September 11, 2008
    Publication date: January 8, 2009
    Applicant: JOHN WAYNE CANCER INSTITUTE
    Inventors: David Hoon, Bret Taback, Samuel Shaolian