Patents by Inventor Samuel T. ALBRIGHT

Samuel T. ALBRIGHT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SELECTIVE BTK IRREVERSIBLE INHIBITORS
    Publication number: 20220306638
    Abstract: The invention provides a series of conformationally stable and selective, irreversible kinase inhibitors, and methods of using the kinase inhibitors. The effect of atropisomerism on kinase selectivity was assessed, finding improved selectivity compared to rapidly interconverting parent compounds. The compounds herein are atropisomers having increased kinase selectivity and are for use in treating conditions that benefit from selective BTK kinase inhibition.
    Type: Application
    Filed: June 23, 2020
    Publication date: September 29, 2022
    Applicant: SAN DIEGO STATE UNIVERSITY FOUNDATION
    Inventors: Jeffrey L. GUSTAFSON, Sean Thomas TOENJES, Samuel T. ALBRIGHT, Ramsey HAZIN