Patents by Inventor Samuel W. Gerritz

Samuel W. Gerritz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphatase Binding Compounds and Methods of Using Same
    Publication number: 20200268897
    Abstract: The present invention provides bifunctional compounds that efficiently dephosphorylate certain phospho-activated target proteins. Such target proteins can be any protein involved in the pathway of a disease or disorder, such as but not limited to cancer, neurodegeneration, metabolic disease, diabetes, insulin resistance, and so forth.
    Type: Application
    Filed: January 8, 2020
    Publication date: August 27, 2020
    Inventors: Craig Crews, Samuel W. Gerritz, Kyle J. Eastman, Katherine J. Kayser-Bricker, Jinshan M. Chen, David E. Puleo
  • Methods and compositions for inhibition of the transitional endoplasmic reticulum ATPase
    Patent number: 8865708
    Abstract: Compounds of Formulas I-XLIII are identified as direct inhibitors of p97 ATPase or of the degradation of a p97-dependent ubiquitin-proteasome system (UPS) substrate. Methods and compositions are disclosed for inhibiting p97 ATPase and the degradation of a p97-dependent UPS substrate, and for identifying inhibitors thereof.
    Type: Grant
    Filed: May 6, 2011
    Date of Patent: October 21, 2014
    Assignees: California Institute of Technology, The University of Kansas, Cleave Biosciences, Inc.
    Inventors: Raymond J. Deshaies, Tsui-Fen Chou, Frank J. Schoenen, Kelin Li, Kevin J. Frankowski, Jeffrey Aube, Samuel W. Gerritz, Han-Jie Zhou
  • METHODS AND COMPOSITIONS FOR INHIBITION OF THE TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE
    Publication number: 20110288082
    Abstract: Compounds of Formulas I-XLIII are identified as direct inhibitors of p97 ATPase or of the degradation of a p97-dependent ubiquitin-proteasome system (UPS) substrate.
    Type: Application
    Filed: May 6, 2011
    Publication date: November 24, 2011
    Inventors: Raymond J. Deshaies, Tsui-Fen Chou, Frank J. Schoenen, Kelin Li, Kevin J. Frankowski, Jeffrey Aube, Samuel W. Gerritz, Han-Jie Zhou