Patents by Inventor Samuel Wright
Samuel Wright has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240103287Abstract: A removable facial interface for a head-mountable device (HMD) is disclosed. In an example, an HMD includes a display; a facial interface frame at least partially surrounding the display; a removable facial interface attached to the facial interface frame; a first attachment mechanism attached to one of the facial interface frame or the removable facial interface; and a second attachment mechanism attached to the other of the facial interface frame or the removable facial interface, the removable facial interface being attached to the facial interface frame by the first attachment mechanism and the second attachment mechanism.Type: ApplicationFiled: September 19, 2023Publication date: March 28, 2024Inventors: Erin M. Bosch, Darshan R. Kasar, Timon A. Wright, Nicholas R. Trincia, Jonathan M. Anderson, Liam R. Martinez, Ian A. Guy, Paul X. Wang, Samuel G. Smith, Jeffrey A. Griffis, Andrew Gallaher
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Publication number: 20240068363Abstract: A drilling assembly for downhole to surface communications is provided. The drilling assembly includes a series of pipe segments coupled in fluid communication between a slip ring assembly and an end pipe portion. The slip ring assembly is coupled in data and fluid communication with the pipe segments. A surface communications link is in data communication with the drilling assembly via the slip ring assembly. An end pipe portion is coupled with the drilling assembly that includes an electronics assembly with electronic components for transferring data to the slip ring assembly via the drilling assembly. A drill bit is operably coupled with the end pipe portion for drilling a borehole. Each pipe segment includes an outer conductor portion, a hollow inner conductor portion, and a dielectric portion for electrical isolation between the outer conductor portion and the inner conductor portion.Type: ApplicationFiled: November 6, 2023Publication date: February 29, 2024Inventors: Jiann-Cherng Su, Jason P. Krein, John Joseph Borchardt, Richard Ellis Robey, Andrew Alexander Wright, Joseph Samuel Pope, Taylor Anthony Myers, Mark C. Grubelich, Douglas A. Blankenship
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Patent number: 11723953Abstract: A reconstituted high density lipoprotein formulation having relatively low toxicity comprises an apolipoprotein such as ApoAI or fragment thereof, a lipid and a detergent at a level which is about 5-50% of that which would normally cause liver toxicity upon administration to a human. The lipid is optimally phosphatidylcholine at about 30-50 g/L and the molar ratio of apolipoprotein:lipid is optimally in the range 1:40 to 1:75. The formulation is useful for treating diseases or conditions such as cardiovascular disease, hypercholesterolaemia and hypocholesterolaemia inclusive of acute coronary syndrome (ACS), atherosclerosis and myocardial infarction.Type: GrantFiled: July 6, 2021Date of Patent: August 15, 2023Assignee: CSL LimitedInventors: Samuel Wright, Martin Imboden, Reinhard Bolli, Marcel Waelchli
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Publication number: 20220133852Abstract: A reconstituted high density lipoprotein formulation having relatively low toxicity comprises an apolipoprotein such as ApoAI or fragment thereof, a lipid and a detergent at a level which is about 5-50% of that which would normally cause liver toxicity upon administration to a human. The lipid is optimally phosphatidylcholine at about 30-50 g/L and the molar ratio of apolipoprotein:lipid is optimally in the range 1:40 to 1:75. The formulation is useful for treating diseases or conditions such as cardiovascular disease, hypercholesterolaemia and hypocholesterolaemia inclusive of acute coronary syndrome (ACS), atherosclerosis and myocardial infarction.Type: ApplicationFiled: July 6, 2021Publication date: May 5, 2022Applicant: CSL LimitedInventors: Samuel Wright, Martin Imboden, Reinhard Bolli, Marcel Waelchli
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Publication number: 20210269517Abstract: The present disclosure provides a method of treating a wasting disorder in a subject, the method comprising administering to the subject a compound that inhibits VEGF-B signalling. The present disclosure also provides a method of treating cancer cachexia in a subject suffering from cancer cachexia, the method comprising 5 administering to the subject a compound that inhibits VEGF-B signaling.Type: ApplicationFiled: September 18, 2019Publication date: September 2, 2021Applicants: CSL Limited, CSL Innovation Pty Ltd, B-Creative Sweden ABInventors: Ulf ERIKSSON, Annelie FALKEVALL, Annika MEHLEM, Isolde PALOMBO, Samuel WRIGHT
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Patent number: 11058747Abstract: A reconstituted high density lipoprotein formulation having relatively low toxicity comprises an apolipoprotein such as ApoAI or fragment thereof, a lipid and a detergent at a level which is about 5-50% of that which would normally cause liver toxicity upon administration to a human. The lipid is optimally phosphatidylcholine at about 30-50 g/L and the molar ratio of apolipoprotein:lipid is optimally in the range 1:40 to 1:75. The formulation is useful for treating diseases or conditions such as cardiovascular disease, hypercholesterolaemia and hypocholesterolaemia inclusive of acute coronary syndrome (ACS), atherosclerosis and myocardial infarction.Type: GrantFiled: June 19, 2019Date of Patent: July 13, 2021Assignee: CSL LIMITEDInventors: Samuel Wright, Martin Imboden, Reinhard Bolli, Marcel Waelchli
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Publication number: 20200294664Abstract: The present disclosure provides a computer-implemented method of graphically representing events relating to a plurality of users. The method comprises: graphically representing a knowledge base, the knowledge base comprising concepts that are linked by relations; receiving a plurality of interim graphs each relating to an event, said interim graphs each comprising a plurality of nodes including a node identifying the user associated with the event and a node identifying a concept describing an outcome of the event; linking the plurality of interim graphs with the knowledge base to form a relation between the nodes in the interim graphs identifying the concepts and corresponding concepts in the knowledge base to produce a graphical representation of a user profile including the knowledge base augmented with the interim graphs relating to a plurality of users.Type: ApplicationFiled: March 14, 2019Publication date: September 17, 2020Inventors: Georgios STOILOS, Domenico CORAPI, Hugh SIMPSON, Forat LATIF, Chun Lok LING, Szymon WARTAK, Samuel WRIGHT, Mohammad KHODADADI
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Publication number: 20200294666Abstract: The present disclosure provides a computer-implemented method of building a user profile for a medical diagnostic system. The method includes receiving a new event including data describing a consultation with the user from a conversation module of the diagnostic system. The method also includes encoding the new event using JavaScript Object Notation (JSON). The method also includes storing the encoded new event in a queue of events. The method also includes decoding and translating the new event into a form compatible with the user profile. The method also includes adding the translated new event to the user profile.Type: ApplicationFiled: April 4, 2019Publication date: September 17, 2020Inventors: Georgios STOILOS, Domenico CORAPI, Hugh SIMPSON, Forat LATIF, Chun Lok LING, Szymon WARTAK, Samuel WRIGHT, Mohammad KHODADADI
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Publication number: 20200171126Abstract: A reconstituted high density lipoprotein formulation having relatively low toxicity comprises an apolipoprotein such as ApoAI or fragment thereof, a lipid and a detergent at a level which is about 5-50% of that which would normally cause liver toxicity upon administration to a human. The lipid is optimally phosphatidylcholine at about 30-50 g/L and the molar ratio of apolipoprotein:lipid is optimally in the range 1:40 to 1:75. The formulation is useful for treating diseases or conditions such as cardiovascular disease, hypercholesterolaemia and hypocholesterolaemia inclusive of acute coronary syndrome (ACS), atherosclerosis and myocardial infarction.Type: ApplicationFiled: June 19, 2019Publication date: June 4, 2020Applicant: CSL LimitedInventors: Samuel Wright, Martin Imboden, Reinhard Bolli, Marcel Waelchli
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Publication number: 20200038481Abstract: Reconstituted HDL formulations, methods of treatment comprising same and uses thereof are provided for treating patients after an acute myocardial infarction (MI) event. The reconstituted HDL formulations comprise an apo lipoprotein, a lipid, a detergent and a stabilizer such as sucrose. Treatment of MI patients with repeated infusions of rHDL enhance cholesterol efflux capacity and do not produce significant alterations in liver or kidney function. The MI patient may have normal kidney function or moderate renal impairment.Type: ApplicationFiled: November 10, 2017Publication date: February 6, 2020Applicant: CSL LIMITEDInventors: Samuel Wright, Charles Shear, Denise D'Andrea, Andreas Gille, Danielle Duffy
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Patent number: 10335457Abstract: A reconstituted high density lipoprotein formulation having relatively low toxicity comprises an apolipoprotein such as ApoAI or fragment thereof, a lipid and a detergent at a level which is about 5-50% of that which would normally cause liver toxicity upon administration to a human. The lipid is optimally phosphatidylcholine at about 30-50 g/L and the molar ratio of apolipoprotein:lipid is optimally in the range 1:40 to 1:75. The formulation is useful for treating diseases or conditions such as cardiovascular disease, hypercholesterolaemia and hypocholesterolaemia inclusive of acute coronary syndrome (ACS), atherosclerosis and myocardial infarction.Type: GrantFiled: August 19, 2016Date of Patent: July 2, 2019Assignee: CSL LIMITEDInventors: Samuel Wright, Martin Imboden, Reinhard Bolli, Marcel Waelchli
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Publication number: 20170196935Abstract: A reconstituted high density lipoprotein formulation having relatively low toxicity comprises an apolipoprotein such as ApoAI or fragment thereof, a lipid and a detergent at a level which is about 5-50% of that which would normally cause liver toxicity upon administration to a human. The lipid is optimally phosphatidylcholine at about 30-50 g/L and the molar ratio of apolipoprotein:lipid is optimally in the range 1:40 to 1:75. The formulation is useful for treating diseases or conditions such as cardiovascular disease, hypercholesterolaemia and hypocholesterolaemia inclusive of acute coronary syndrome (ACS), atherosclerosis and myocardial infarction.Type: ApplicationFiled: August 19, 2016Publication date: July 13, 2017Inventors: Samuel Wright, Martin Imboden, Reinhard Bolli, Marcel Waelchli
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Patent number: 9439946Abstract: A reconstituted high density lipoprotein formulation having relatively low toxicity comprises an apolipoprotein such as ApoAI or fragment thereof, a lipid and a detergent at a level which is about 5-50% of that which would normally cause liver toxicity upon administration to a human. The lipid is optimally phosphatidylcholine at about 30-50 g/L and the molar ratio of apolipoprotein:lipid is optimally in the range 1:40 to 1:75. The formulation is useful for treating diseases or conditions such as cardiovascular disease, hypercholesterolaemia and hypocholesterolaemia inclusive of acute coronary syndrome (ACS), atherosclerosis and myocardial infarction.Type: GrantFiled: February 27, 2015Date of Patent: September 13, 2016Assignee: CSL LIMITEDInventors: Samuel Wright, Martin Imboden, Reinhard Bolli, Marcel Waelchli
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Publication number: 20160022768Abstract: A reconstituted high density lipoprotein formulation having relatively low toxicity comprises an apolipoprotein such as ApoAI or fragment thereof, a lipid and a detergent at a level which is about 5-50% of that which would normally cause liver toxicity upon administration to a human. The lipid is optimally phosphatidylcholine at about 30-50 g/L and the molar ratio of apolipoprotein:lipid is optimally in the range 1:40 to 1:75. The formulation is useful for treating diseases or conditions such as cardiovascular disease, hypercholesterolaemia and hypocholesterolaemia inclusive of acute coronary syndrome (ACS), atherosclerosis and myocardial infarction.Type: ApplicationFiled: February 27, 2015Publication date: January 28, 2016Applicant: CSL LimitedInventors: Samuel Wright, Martin Imboden, Reinhard Bolli, Marcel Waelchli
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Patent number: 8999920Abstract: A reconstituted high density lipoprotein formulation having relatively low toxicity comprises an apolipoprotein such as ApoAI or fragment thereof, a lipid and a detergent at a level which is about 5-50% of that which would normally cause liver toxicity upon administration to a human. The lipid is optimally phosphatidylcholine at about 30-50 g/L and the molar ratio of apolipoprotein:lipid is optimally in the range 1:40 to 1:75. The formulation is useful for treating diseases or conditions such as cardiovascular disease, hypercholesterolaemia and hypocholesterolaemia inclusive of acute coronary syndrome (ACS), atherosclerosis and myocardial infarction.Type: GrantFiled: June 30, 2011Date of Patent: April 7, 2015Assignee: CSL LimitedInventors: Samuel Wright, Martin Imboden, Reinhard Bolli, Marcel Waelchli
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Publication number: 20130190226Abstract: A reconstituted high density lipoprotein formulation having relatively low toxicity comprises an apolipoprotein such as ApoAI or fragment thereof, a lipid and a detergent at a level which is about 5-50% of that which would normally cause liver toxicity upon administration to a human. The lipid is optimally phosphatidylcholine at about 30-50 g/L and the molar ratio of apolipoprotein:lipid is optimally in the range 1:40 to 1:75. The formulation is useful for treating diseases or conditions such as cardiovascular disease, hypercholesterolaemia and hypocholesterolaemia inclusive of acute coronary syndrome (ACS), atherosclerosis and myocardial infarction.Type: ApplicationFiled: June 30, 2011Publication date: July 25, 2013Inventors: Samuel Wright, Martin Imboden, Reinhard Bolli, Marcel Waelchli
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Publication number: 20040242459Abstract: A method for treating, controlling, preventing or reducing the risk of contracting an inflammatory disease or condition in a mammalian patient, comprises the steps of (1) selecting a patient in need thereof, and (2) treating the patient with a therapeutically effective amount of a composition comprising a PPAR-&dgr; agonist. Inflammatory diseases that may be treated by this method include but are not limited to rheumatoid arthritis, juvenile rheumatoid arthritis, systemic lupus erythematosus, osteoarthritis, degenerative joint disease, one or more connective tissue diseases, ankylosing spondylitis, and bursitis.Type: ApplicationFiled: December 9, 2003Publication date: December 2, 2004Inventors: Michael J Forrest, Joel P Berger, David E Moller, Samuel Wright
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Patent number: D663119Type: GrantFiled: September 22, 2011Date of Patent: July 10, 2012Inventor: Samuel Wright