Abstract: The present invention relates to a composition for preventing, improving, or treating diseases related to advanced glycation end products, comprising an indole derivative or a pharmaceutically acceptable salt thereof. Specifically, the composition of the present invention possesses the effect of trapping methylglyoxal (MGO), which is a main precursor of advanced glycation end products, and thus can be effectively used for preventing, improving, or treating diseases related to advanced glycation end products.

Abstract: The present invention relates to a novel indole derivative and a use thereof. The novel indole derivative according to the present invention traps methylglyoxal (MGO), which is a main precursor of advanced glycation end products, and thus can be effectively used for preventing, improving, or treating diseases related to advanced glycation end products.

Abstract: A scanning probe microscope has a tilting stage on which a sample is mounted. The sample is scanned back and forth with the stage being tilted clockwise during a forward scan and counterclockwise during a reverse scan. A first surface contour of the sample is determined from the response of the probe and the tilt angle of the stage during the forward scan. A second surface contour of the sample is determined from the response of the probe and the tilt angle of the stage during the reverse scan. A final surface contour of the sample is obtained by combining the first and second surface contours.

Abstract: A heat exchanger having corrosion resistant resin-coated plates and pipes. The heat exchanger is easily constructed using the corrosion resistant resin-coated plates and the pipes. The heat exchanger does not require heat treatments or large constructing sections. In the heat exchanger according to the present invention, a gas is supplied to the outside of pipes, and air and/or water are passed through the pipes. As a result, heat change is accomplished. A pipe plate and a side wall of the heat exchanger are coated with Teflon or a heat resistant resin. In the feed water pre-heater for heating water, pipes are formed as metal pipes coated with a resin for maintaining the strength of the pipes. Thereafter, the pipes are individually welded and fabricated. In the feed air pre-heater, the heat exchanger has side walls, a pipe plate and pipes. The side walls and the pipe plate have essentially the same structure. The pipes are made of resin. The pipe plate and pipes are united by a metal assembling member.