Patents by Inventor San-Lian S. Barbour

San-Lian S. Barbour has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for uncovering deeply hidden enzyme-like behaviors from physiological time-series measures for disease detection, monitoring and other applications
    Patent number: 11179073
    Abstract: A method of determining structured behavior from network adjacency matrices is described. A method of detecting physiological signals from a subject is described.
    Type: Grant
    Filed: April 7, 2021
    Date of Patent: November 23, 2021
    Assignees: Photon Migration Technologies Corp., SLB Inspirations Ltd.
    Inventors: Randall L. Barbour, San-Lian S. Barbour, Harry L. Graber
  • METHOD FOR UNCOVERING DEEPLY HIDDEN ENZYME-LIKE BEHAVIORS FROM PHYSIOLOGICAL TIME-SERIES MEASURES FOR DISEASE DETECTION, MONITORING AND OTHER APPLICATIONS
    Publication number: 20210321915
    Abstract: A method of determining structured behavior from network adjacency matrices is described. A method of detecting physiological signals from a subject is described.
    Type: Application
    Filed: April 7, 2021
    Publication date: October 21, 2021
    Inventors: Randall L. Barbour, San-Lian S. Barbour, Harry L. Graber
  • Method for representations of network-dependent features of the hemoglobin signal in living tissues for detection of breast cancer and other applications
    Patent number: 11129565
    Abstract: A non-invasive method of detecting anomalous tissue, such as cancerous or injured tissue, in a patient. At least two hemoglobin signal components of hemoglobin levels in at least one segment of tissue of the patient are non-invasively measured over time. Time varying changes of at least a first of the hemoglobin signal components are measured with respect to at least time varying changes of a second of the hemoglobin signal components. A co-varying coordinate system of the time varying changes is generated. Any anomalous tissue in the measured segment of tissue is detected from a signature of the measured segment of tissue in the co-varying coordinate system which differs from a signature of non-anomalous tissue in the co-varying coordinate system. Preferably, five hemoglobin signal components are measured: oxyHb, deoxyHb, total Hb (totalHb=oxyHb+deoxy Hb), Hb oxygen saturation (HbO2Sat=(oxyHb/totalHb)*100), and tissue-hemoglobin oxygen exchange HbO2Exc (deoxyHb?oxyHb).
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: September 28, 2021
    Assignees: Photon Migration Technologies Corp., SLB Innovations Group, LLC
    Inventors: Randall L. Barbour, Harry L. Graber, San-Lian S. Barbour
  • Method for representations of network-dependent features of the hemoglobin signal in living tissues for detection of breast cancer and other applications
    Publication number: 20190117146
    Abstract: A non-invasive method of detecting anomalous tissue, such as cancerous or injured tissue, in a patient. At least two hemoglobin signal components of hemoglobin levels in at least one segment of tissue of the patient are non-invasively measured over time. Time varying changes of at least a first of the hemoglobin signal components are measured with respect to at least time varying changes of a second of the hemoglobin signal components. A co-varying coordinate system of the time varying changes is generated. Any anomalous tissue in the measured segment of tissue is detected from a signature of the measured segment of tissue in the co-varying coordinate system which differs from a signature of non-anomalous tissue in the co-varying coordinate system. Preferably, five hemoglobin signal components are measured: oxyHb, deoxyHb, total Hb (totalHb=oxyHb+deoxy Hb), Hb oxygen saturation (HbO2Sat=(oxyHb/totalHb)*100), and tissue-hemoglobin oxygen exchange HbO2Exc (deoxyHb?oxyHb).
    Type: Application
    Filed: October 23, 2018
    Publication date: April 25, 2019
    Inventors: Randall L. Barbour, Harry L. Graber, San-Lian S. Barbour
  • Method for representations of network-dependent features of the hemoglobin signal in living tissues for detection of breast cancer and other applications
    Patent number: 10105090
    Abstract: A non-invasive method of detecting anomalous tissue, such as cancerous or injured tissue, in a patient. At least two hemoglobin signal components of hemoglobin levels in at least one segment of tissue of the patient are non-invasively measured over time. Time varying changes of at least a first of the hemoglobin signal components are measured with respect to at least time varying changes of a second of the hemoglobin signal components. A co-varying coordinate system of the time varying changes is generated. Any anomalous tissue in the measured segment of tissue is detected from a signature of the measured segment of tissue in the co-varying coordinate system which differs from a signature of non-anomalous tissue in the co-varying coordinate system. Preferably, five hemoglobin signal components are measured: oxyHb, deoxyHb, total Hb (totalHb=oxyHb+deoxy Hb), Hb oxygen saturation (HbO2Sat=(oxyHb/totalHb)*100), and tissue-hemoglobin oxygen exchange HbO2Exc (deoxyHb?oxyHb).
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: October 23, 2018
    Assignees: Photon Migration Technologies Corp., SLB Innovations Group, LLC
    Inventors: Randall L. Barbour, Harry L. Graber, San-Lian S. Barbour
  • Method for representations of network-dependent features of the hemoglobin signal in living tissues for detection of breast cancer and other applications
    Publication number: 20180110458
    Abstract: A non-invasive method of detecting anomalous tissue, such as cancerous or injured tissue, in a patient. At least two hemoglobin signal components of hemoglobin levels in at least one segment of tissue of the patient are non-invasively measured over time. Time varying changes of at least a first of the hemoglobin signal components are measured with respect to at least time varying changes of a second of the hemoglobin signal components. A co-varying coordinate system of the time varying changes is generated. Any anomalous tissue in the measured segment of tissue is detected from a signature of the measured segment of tissue in the co-varying coordinate system which differs from a signature of non-anomalous tissue in the co-varying coordinate system. Preferably, five hemoglobin signal components are measured: oxyHb, deoxyHb, total Hb (totalHb=oxyHb+deoxy Hb), Hb oxygen saturation (HbO2Sat=(oxyHb/totalHb)*100), and tissue-hemoglobin oxygen exchange HbO2Exc (deoxyHb?oxyHb).
    Type: Application
    Filed: October 13, 2017
    Publication date: April 26, 2018
    Inventors: Randall L. Barbour, Harry L. Graber, San-Lian S. Barbour