Patents by Inventor Sanbing Shen

Sanbing Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRANSGENIC RODENT EXPRESSING TRUNCATED DISC1
    Publication number: 20120304317
    Abstract: The invention provides transgenic rodents, particularly mice, expressing truncated versions of the Disrupted-in-Schizophrenia-1 (DISC1) gene and showing Schizophrenia-related neural and behavioral phenotypes. The rodents of the invention have (1) a plurality of copies of a heterologous truncated Disc1 genomic DNA sequence which includes at least 1 stop codon after exon 8 such as to encode a Disc1 polypeptide truncated before exon 9; (2) 2 copies of endogenous Disc1 genomic DNA sequence encoding full length Disc1 polypeptide. Also provided are related materials and methods.
    Type: Application
    Filed: July 16, 2009
    Publication date: November 29, 2012
    Applicants: THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN, WYETH PHARMACEUTICALS INC., TMRI LIMITED
    Inventors: Sanbing Shen, Gernot Riedel, David St. Clair