Abstract: A system for facial analysis includes a camera, a data storage device and a data processing system. The camera takes video of a subject's face, and the data storage device receives and stores the video. The data processing system extracts a pose of the subject's face, and a representation of the subject's facial gesture state. The pose includes the angle and position of the subject's face. The representation includes facial keypoints that are a collection of points on the subject's face. The system then concatenates each data stream to align the data streams in time, extracts a plurality of facial syllables from the aligned data streams, and compiles the facial syllables into a series of state sequences. Based on the series of state sequences, the system extracts a behavioral fingerprint for the subject that provides a summary of the subject's state over a given period of time.

Abstract: A system for facial analysis includes a camera, a data storage device and a data processing system. The camera takes video of a subjects face, and the data storage device receives and stores the video. The data processing system extracts a pose of the subjects face, and a representation of the subjects facial gesture state. The pose includes the angle and position of the subjects face. The representation includes facial keypoints that are a collection of points on the subjects face. The system then concatenates each data stream to align the data streams in time, extracts a plurality of facial syllables from the aligned data streams, and compiles the facial syllables into a series of state sequences. Based on the series of state sequences, the system extracts a behavioral fingerprint for the subject that provides a summary of the subjects state over a given period of time.

Abstract: Provided herein are methods of treating Alzheimer's disease, atopy, allergies, asthma, and a disease or disorder associated with neuroinflammation by modulating MS4A receptors. Also found herein are methods of modulating olfactory and gustatory properties of a substance by modulating MS4A receptors. Additionally, described herein are methods of identifying agents that are modulators of MS4A receptors.