Patents by Inventor Sandeep Rana

Sandeep Rana has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOTREXATE ANALOGS AND METHODS OF USE
    Publication number: 20230406859
    Abstract: Compounds having general formula I or a pharmaceutically acceptable salt, N-oxide, or hydrate thereof are provided herein. Also provided are methods of making the compounds and methods of their use, including in treatment of cancer, autoimmune disorders, and viral infections.
    Type: Application
    Filed: June 22, 2021
    Publication date: December 21, 2023
    Applicant: The United States of America, as represented by the Secretary, Dept. of Health and Human Services
    Inventors: James Inglese, Ganesha Rai Bantukallu, Sandeep Rana, Laurence Lamy
  • Dimers of covalent NFKB inhibitors
    Patent number: 11840540
    Abstract: Provided herein are compounds and methods for modulating the NF?B pathway. More particularly, provided are inhibitors of the NF?B pathway and the uses of such inhibitors in regulating diseases and disorders, e.g., to treat cancer, autoimmune diseases, inflammatory diseases, diabetes, cardiovascular diseases, or neurological diseases.
    Type: Grant
    Filed: July 21, 2021
    Date of Patent: December 12, 2023
    Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventors: Amarnath Natarajan, Sandeep Rana
  • Dimers of Covalent NFKB Inhibitors
    Publication number: 20220009941
    Abstract: Provided herein are compounds and methods for modulating the NF?B pathway. More particularly, provided are inhibitors of the NF?B pathway and the uses of such inhibitors in regulating diseases and disorders, e.g., to treat cancer, autoimmune diseases, inflammatory diseases, diabetes, cardiovascular diseases, or neurological diseases.
    Type: Application
    Filed: July 21, 2021
    Publication date: January 13, 2022
    Inventors: Amarnath Natarajan, Sandeep Rana
  • Dimers of covalent NFKB inhibitors
    Patent number: 11104684
    Abstract: Provided herein are compounds and methods for modulating the NF?B pathway. More particularly, provided are inhibitors of the NF?B pathway and the uses of such inhibitors in regulating diseases and disorders, e.g., to treat cancer, autoimmune diseases, inflammatory diseases, diabetes, cardiovascular diseases, or neurological diseases.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: August 31, 2021
    Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventors: Amarnath Natarajan, Sandeep Rana
  • Dimers of Covalent NFKB Inhibitors
    Publication number: 20190322680
    Abstract: Provided herein are compounds and methods for modulating the NFKB pathway. More particularly, provided are inhibitors of the NFKB pathway and the uses of such inhibitors in regulating diseases and disorders, e.g., to treat cancer, autoimmune diseases, inflammatory diseases, diabetes, cardiovascular diseases, or neurological diseases.
    Type: Application
    Filed: December 21, 2017
    Publication date: October 24, 2019
    Inventors: Amarnath Natarajan, Sandeep Rana