Patents by Inventor Sandeep S. Karajanagi

Sandeep S. Karajanagi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enhanced stability of proteins immobilized on nanoparticles
    Patent number: 9360475
    Abstract: This invention is directed to the application of a previously unknown property of nanomaterials—its ability to enhance protein activity and stability at high temperatures, in organic solvents, and in polymer composites. Nanomaterials such as single-walled carbon nanotubes (SWNTs) can significantly enhance enzyme function and stability in strongly denaturing environments. Experimental results and theoretical analysis reveal that the enhancement in stability is a result of the curvature of these nanoscale materials, which suppresses unfavorable protein-protein interactions.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: June 7, 2016
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Jonathan S. Dordick, Ravindra S. Kane, Prashanth Asuri, Sandeep S. Karajanagi, Alexey A. Vertegel, Richard W. Siegel
  • Enhanced Stability of Proteins Immobilized on Nanoparticles
    Publication number: 20120301870
    Abstract: This invention is directed to the application of a previously unknown property of nanomaterials—its ability to enhance protein activity and stability at high temperatures, in organic solvents, and in polymer composites. Nanomaterials such as single-walled carbon nanotubes (SWNTs) can significantly enhance enzyme function and stability in strongly denaturing environments. Experimental results and theoretical analysis reveal that the enhancement in stability is a result of the curvature of these nanoscale materials, which suppresses unfavorable protein-protein interactions.
    Type: Application
    Filed: April 26, 2012
    Publication date: November 29, 2012
    Inventors: Jonathan S. Dordick, Ravindra S. Kane, Prashanth Asuri, Sandeep S. Karajanagi, Alexey A. Vertegel, Richard W. Siegel
  • Enhanced stability of proteins immobilized on nanoparticles
    Publication number: 20090143487
    Abstract: This invention is directed to the application of a previously unknown property of nanomaterials—its ability to enhance protein activity and stability at high temperatures, in organic solvents, and in polymer composites. Nanomaterials such as single-walled carbon nanotubes (SWNTs) can significantly enhance enzyme function and stability in strongly denaturing environments. Experimental results and theoretical analysis reveal that the enhancement in stability is a result of the curvature of these nanoscale materials, which suppresses unfavorable protein-protein interactions. The enhanced stability is also exploited in the preparation of highly stable and active nanocomposite films that resist nonspecific protein absorption, i.e., inhibit fouling of the films. The protein-nanoparticles conjugates represent a new generation of highly selective, active, and stable catalytic materials.
    Type: Application
    Filed: September 7, 2005
    Publication date: June 4, 2009
    Inventors: Jonathan S. Dordick, Ravindra S. Kane, Prashanth Asuri, Sandeep S. Karajanagi