Patents by Inventor Sandeep Tharian Koshy

Sandeep Tharian Koshy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS
    Publication number: 20250000973
    Abstract: The invention provides methods of making immune effector cells (for example, T cells, NK cells) that express a chimeric antigen receptor (CAR), and compositions generated by such methods.
    Type: Application
    Filed: August 19, 2022
    Publication date: January 2, 2025
    Inventors: Michael Bardroff, Regis Cebe, Brian Walter Granda, Shyamali Jayashankar, Sandeep Tharian Koshy, Sandra Miller, Andrew Patrick Price, Amy Rayo, Darko Skegro, Louise Mary Treanor, Jennifer Yang
  • COMPOSITIONS AND METHODS FOR IN VIVO GENERATION OF CAR EXPRESSING CELLS
    Publication number: 20230302155
    Abstract: Aspects of this disclosure relate generally to the use of biomaterials for the in vivo generation of CAR expressing cells. In some embodiments, the biomaterials comprise one or more of a cell recruitment composition, a viral vector, and/or a cell activation agent.
    Type: Application
    Filed: August 20, 2021
    Publication date: September 28, 2023
    Inventors: Sandeep Tharian Koshy, Glenn Dranoff, Maria Anna Sofia Broggi, Chris Bridgeman, Stephen Michael Canham, Yoel Melles, Regis Cebe, Brian Walter Granda, Louise Mary Treanor, Shyamali Jayashankar, Jennifer Yang, Amy Rayo, Andrew Patrick Price, Darko Skegro, Justine Guyot, Tushar Dattu Apsunde, Cameron Chuck-munn Lee, Michael Bardroff, Sandra Miller
  • MESOPOROUS SILICA PARTICLES COMPOSITIONS FOR VIRAL DELIVERY
    Publication number: 20220152150
    Abstract: The present invention relates generally to the use of compositions including mesoporous silica particles that may be surface modified, for the delivery of viral vectors. In some embodiments, the viral vectors are used to transduce T cells to express a chimeric antigen receptor (CAR), to treat a subject having a disease, e.g., a disease associated with expression of a tumor antigen.
    Type: Application
    Filed: February 24, 2020
    Publication date: May 19, 2022
    Inventors: Sandeep Tharian Koshy, Stephen M. Canham