Abstract: A system enabling hands-free operation of controls for accessing a transportation vehicle is provided. The system comprises code readers associated with respective entry barriers for admitting passengers to a transportation vehicle. The code readers read a machine-readable passenger code generated by a mobile electronic device and actuate mechanisms allowing entry through the barriers responsive confirmation of the code. A signal receiver in communication with a Passenger Service Unit for passenger seat onboard the vehicle receives instructions from the mobile electronic device and instruct the PSU to actuate passenger cabin controls for the passenger seat. An application on the mobile electronic device determines a time-stamped temperature of a passenger and generates the passenger code, which includes passenger identification, authorization to pass through the entry barriers and board the vehicle, and a determination if the temperature of the passenger indicates an acceptable passenger health status.

Abstract: Methods for generating/expanding populations of immune cells comprising immune cells specific for an Epstein Barr Virus (EBV) lytic antigen are disclosed, the methods comprising stimulating immune cells specific for an EBV lytic antigen by contacting peripheral blood mononuclear cells (PBMCs) with: (i) one or more peptides corresponding to all or part of one or more EBV lytic antigens; or (ii) antigen presenting cells (APCs) presenting one or more peptides corresponding to all or part of one or more EBV lytic antigens. Also disclosed are populations of immune cells comprising immune cells specific for an EBV lytic antigen expanded according to such methods, and uses thereof.

Abstract: Embodiments of the disclosure concern methods and compositions for immunotherapy for diseases and malignancies associated with viruses other than HPV or with non-virus-associated diseases and malignancies, such as wherein the VST encodes a CAR specific for a non-viral cancer and the VST can be stimulated in vitro or in vivo using viruses, viral vaccines or oncolytic viruses. In specific embodiments, methods concern production of immune cells that target one or more antigens of HIV, EBV, CMV, adenovirus, vaccinia virus, and/or VZV, including methods with stimulation steps that employ IL-7 and IL-15, but not IL-2, IL-4, or both. Other specific embodiments utilize stimulations in the presence of certain cells, such as costimulatory cells and certain antigen presenting cells.

Abstract: A system enabling hands-free operation of controls for accessing a transportation vehicle is provided. The system comprises code readers associated with respective entry barriers for admitting passengers to a transportation vehicle. The code readers read a machine-readable passenger code generated by a mobile electronic device and actuate mechanisms allowing entry through the barriers responsive confirmation of the code. A signal receiver in communication with a Passenger Service Unit for passenger seat onboard the vehicle receives instructions from the mobile electronic device and instruct the PSU to actuate passenger cabin controls for the passenger seat. An application on the mobile electronic device determines a time-stamped temperature of a passenger and generates the passenger code, which includes passenger identification, authorization to pass through the entry barriers and board the vehicle, and a determination if the temperature of the passenger indicates an acceptable passenger health status.

Abstract: Embodiments of the disclosure concern methods and compositions for immunotherapy for human papillomavirus infection and diseases associated therewith. In specific embodiments, methods concern production of immune cells that target one or more antigens of HPV16 and/or HPV18, including methods with stimulation steps that employ IL-7 and IL-15, but not IL-6 and/or IL-12. Other specific embodiments utilize stimulations in the presence of certain cells, such as costimulatory cells and certain antigen presenting cells.

Abstract: Methods for generating/expanding populations of immune cells comprising immune cells specific for an Epstein Barr Virus (EBV) lytic antigen are disclosed, the methods comprising stimulating immune cells specific for an EBV lytic antigen by contacting peripheral blood mononuclear cells (PBMCs) with: (i) one or more peptides corresponding to all or part of one or more EBV lytic antigens; or (ii) antigen presenting cells (APCs) presenting one or more peptides corresponding to all or part of one or more EBV lytic antigens. Also disclosed are populations of immune cells comprising immune cells specific for an EBV lytic antigen expanded according to such methods, and uses thereof.

Abstract: Embodiments of the disclosure concern methods and compositions for immunotherapy for human papillomavirus infection and diseases associated therewith. In specific embodiments, methods concern production of immune cells that target one or more antigens of HPV16 and/or HPV18, including methods with stimulation steps that employ IL-7 and IL-15, but not IL-6 and/or IL-12. Other specific embodiments utilize stimulations in the presence of certain cells, such as costimulatory cells and certain antigen presenting cells.

Abstract: Embodiments of the disclosure concern methods and compositions for immunotherapy for diseases and malignancies associated with viruses other than HPV or with non-virus-associated diseases and malignancies, such as wherein the VST encodes a CAR specific for a non-viral cancer and the VST can be stimulated in vitro or in vivo using viruses, viral vaccines or oncolytic viruses. In specific embodiments, methods concern production of immune cells that target one or more antigens of HIV, EBV, CMV, adenovirus, vaccinia virus, and/or VZV, including methods with stimulation steps that employ IL-7 and IL-15, but not IL-2, IL-4, or both. Other specific embodiments utilize stimulations in the presence of certain cells, such as costimulatory cells and certain antigen presenting cells.

Abstract: Embodiments of the disclosure concern methods and compositions for immunotherapy for human papillomavirus infection and diseases associated therewith. In specific embodiments, methods concern production of immune cells that target one or more antigens of HPV16 and/or HPV18, including methods with stimulation steps that employ IL-7 and IL-15, but not IL-6 and/or IL-12. Other specific embodiments utilize stimulations in the presence of certain cells, such as costimulatory cells and certain antigen presenting cells.

Abstract: The liquid steel slag (2) is poured in at least four successive layers (6-8), comprising a lowermost layer (6), an uppermost layer (7) and at least two intermediate layers (8), in a reservoir (3) and the layers of liquid steel slag are allowed to solidify. After having applied the uppermost layer (7), the solidified steel slag is cooled down more quickly by means of water. The average temperature of each of the intermediate layers (8) is kept at least until the start of the water cooling step, and this for at least one hour, above a minimum temperature which is equal to or higher than the temperature at which ?-dicalcium silicate is formed. In this way, more crystalline phases different from dicalcium silicates are formed so that the formation of fines by the transition of ? into ?-dicalcium silicates can be considerably reduced. A glassy material and/or a phosphorus containing compound is preferably added to the liquid slag to further reduce the formation of fines.

Abstract: A method and apparatus are provided for encrypting a stream of data transmitted within a frame. The method includes determining a first initialization state in a first preselected interval, and determining the first initialization state in a second preselected interval, wherein the second preselected interval is less than the first preselected interval. The method includes generating a key stream in response to determining the first initialization state in the second preselected interval, and encrypting at least one bit of the stream of data with at least one bit of the key stream.