Abstract: Disclosed systems and methods include executing a convolutional neural network to detect a level of microbiome in a whole slide image associated with a patient, based on an output of the convolutional neural network, categorize the whole slide image as one of microbiome-low and microbiome-high, and, based on the categorization of the whole slide image, determine a characteristic of a cancer associated with the patient.

Abstract: A multi-layered pharmaceutical delivery system is contemplated in which the delivery of medicaments to patients is controlled via the sequential delivery of medicaments contained within ingestible solid pharmaceutical layers, preferably frozen in a media that liquefies following ingestion by a patient so as to release the medicament when ingested by melting. A frozen ice pop embodiment is contemplated to contain an outermost ingestible pharmaceutical layer enclosing further ingestible pharmaceutical layers sequentially enclosed within that inner pharmaceutical layer. Other embodiments are contemplated in which the layers are linearly sequenced within an external container that prevents ingestion of the subsequent layers until the prior layers have been ingested.

Abstract: The inventive subject matter provides a modular mattress system wherein the mattress surface may be adjusted for positioning of a user's body. The mattress system deploys a number of interconnected mattress cells. The mattress cells may have varying characteristics, and combinations of mattress cells may be interconnected to form a complete mattress. The proximal surface is formed of padding material and collectively form the entire mattress surface when connected. At least one actuator is mechanically coupled to padding material and an actuator controller in communication therewith directs movement of the actuator to position the padding material. A mattress cell communication interface is communicably coupled to the actuator controller and configured to communicably couple with at least one external device.

Abstract: A multi-layered pharmaceutical delivery system is contemplated in which the delivery of medicaments to patients is controlled via the sequential delivery of medicaments contained within ingestible solid pharmaceutical layers, preferably frozen in a media that liquefies following ingestion by a patient so as to release the medicament when ingested by melting. A frozen ice pop embodiment is contemplated to contain an outermost ingestible pharmaceutical layer enclosing further ingestible pharmaceutical layers sequentially enclosed within that inner pharmaceutical layer. Other embodiments are contemplated in which the layers are linearly sequenced within an external container that prevents ingestion of the subsequent layers until the prior layers have been ingested.

Abstract: The inventive subject matter provides a modular mattress system wherein the mattress surface may be adjusted for positioning of a user's body. The mattress system deploys a number of interconnected mattress cells. The mattress cells may have varying characteristics, and combinations of mattress cells may be interconnected to form a complete mattress. The proximal surface is formed of padding material and collectively form the entire mattress surface when connected. At least one actuator is mechanically coupled to padding material and an actuator controller in communication therewith directs movement of the actuator to position the padding material. A mattress cell communication interface is communicably coupled to the actuator controller and configured to communicably couple with at least one external device.