Patents by Inventor Sandra Claudia da Silva Madureira Mendes

Sandra Claudia da Silva Madureira Mendes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell culture medium containing growth factors and L-glutamine
    Patent number: 6838284
    Abstract: The invention relates to a culture medium for culturing cells, in particular human cells in a process for tissue engineering bone. The medium comprises glucose, a mineral, a vitamin, a growth factor and L-glutamine, wherein the L-glutamine is present in a concentration of at least 300 mg/L.
    Type: Grant
    Filed: June 21, 2002
    Date of Patent: January 4, 2005
    Assignee: IsoTis N.V.
    Inventors: Joost Dick de Bruijn, Gerhardus Johannes M. Tibbe, Sandra Claudia da Silva Madureira Mendes
  • Assay for predicting cell activity
    Publication number: 20040171045
    Abstract: The invention relates to a method of determining in vitro the capacity of a cell population to induce bone formation in vivo comprising the steps of: a) providing a sample of a cell population; b) dividing said sample into a first and a second part containing an equal number of cells; c) culturing the first part in the presence of an osteogenic stimulation factor; d) culturing the second part in the absence of an osteogenic stimulation factor; e) determining degrees of expression of a bone-specific protein; and f) comparing the degrees of expression of the bone-specific protein of the first part and the second part thereby providing a measure for the capacity of the bone cell population to induce bone formation in vivo.
    Type: Application
    Filed: December 8, 2003
    Publication date: September 2, 2004
    Applicant: IsoTis N.V.
    Inventors: Joost Dick de Bruijn, Sandra Claudia da Silva Madureira Mendes, Clemens Antoni van Blitterswijk
  • Cell culture medium containing growth factors and L-glutamine
    Publication number: 20030017588
    Abstract: The invention relates to a culture medium for culturing cells, in particular human cells in a process for tissue engineering bone. The medium comprises glucose, a mineral, a vitamin, a growth factor and L-glutamine, wherein the L-glutamine is present in a concentration of at least 300 mg/L.
    Type: Application
    Filed: June 21, 2002
    Publication date: January 23, 2003
    Applicant: IsoTis N.V.
    Inventors: Joost Dick de Bruijn, Gerhardus Johannes M. Tibbe, Sandra Claudia da Silva Madureira Mendes
  • Device for tissue engineering a bone equivalent
    Publication number: 20020028493
    Abstract: The invention relates to a device for tissue engineering a bone equivalent comprising a scaffold material, which scaffold material comprises a matrix based on a destructured, natural, starch-based polymer. The invention further relates to a process for tissue engineering said bone equivalent, a hybrid structure obtainable by said process, and to the use of said hybrid structure in various surgical treatments.
    Type: Application
    Filed: September 11, 2001
    Publication date: March 7, 2002
    Applicant: IsoTis N.V.
    Inventors: Joost Dick de Bruijn, Sandra Claudia da Silva Madureira Mendes, Rui Luis Goncalves dos Reis, Antonio Augusto Magalhaes da Cunha
  • Device for tissue engineering a bone equivalent
    Publication number: 20020028511
    Abstract: The invention relates to a device for tissue engineering a bone equivalent comprising a scaffold material, which scaffold material comprises a matrix based on a destructured, natural, starch-based polymer. The invention further relates to a process for tissue engineering said bone equivalent, a hybrid structure obtainable by said process, and to the use of said hybrid structure in various surgical treatments.
    Type: Application
    Filed: September 11, 2001
    Publication date: March 7, 2002
    Applicant: IsoTis N.V.
    Inventors: Joost Dick de Bruijn, Sandra Claudia da Silva Madureira Mendes, Rui Luis Goncalves dos Reis, Antonio Augusto Magalhaes da Cunha
  • Device for tissue engineering a bone equivalent
    Publication number: 20010021530
    Abstract: The invention relates to a device for tissue engineering a bone equivalent comprising a scaffold material, which scaffold material comprises a matrix based on a destructured, natural, starch-based polymer. The invention further relates to a process for tissue engineering said bone equivalent, a hybrid structure obtainable by said process, and to the use of said hybrid structure in various surgical treatments.
    Type: Application
    Filed: April 24, 2001
    Publication date: September 13, 2001
    Applicant: IsoTis N.V.
    Inventors: Joost Dick de Bruijn, Sandra Claudia da Silva Madureira Mendes, Rui Luis Goncalves dos Reis, Antonio Augusto Magalhaes da Cunha