Abstract: The present invention relates to identification of an abnormal splice site. Provided are methods of identifying an abnormal splice site. Methods of classifying the risk of abnormal splicing of a splice site are also provided. Databases for use in the methods provided herein are also disclosed.

Abstract: A method for determining the likelihood that a genetic variant of a genetic locus defines a genetic disease or cancer-associated allele.

Abstract: This improved version of the Hard Hat Cushioning Device is more universal and can be used with virtually any hard hat, construction hat, bump cap, and similar hats designed for protection. The device allows the hat to fit more comfortably and securely and helps to prevent hair breakage while maintaining its decorative style. The cushioning effect reduces the restriction of blood flow to the scalp. The newly added air vents, and specific cotton outer material and inside batting material, improves air flow and circulation, making the hat more comfortable to wear while allowing warm air and perspiration to escape. These new improvements increase the ability of the cushioning device to act as a sweat band. Allowing air flow from inside the hat to the outside allowing for decreased temperature of the overall hat itself.