Patents by Inventor Sandra Dollet

Sandra Dollet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Screening assay for TLR7, TLR8 and TLR9 agonists and antagonists
    Patent number: 7498409
    Abstract: The present invention relates to novel screening methods for identifying agonists and antagonists of toll-like receptor (TLR) 7, TLR8 or TLR9. Methods are disclosed for identifying agonists and antagonists of TLR7, TLR8 or TLR9 using mutant TLR proteins containing deletions in one or more extracellular leucine rich regions (LRRs). Such agonists and antagonists have utility in the prevention, treatment and/or cure of various diseases and conditions, including cancer, virus infection, allergy, asthma, and chronic obstructive pulmonary disease (COPD).
    Type: Grant
    Filed: March 23, 2006
    Date of Patent: March 3, 2009
    Assignee: Schering Corporation
    Inventors: Jaromir Vlach, Uzma Ayesha Hasan, Sandra Dollet
  • Screening assay for TLR7, TLR8 and TLR9 agonists and antagonists
    Publication number: 20060269936
    Abstract: The present invention relates to novel screening methods for identifying agonists and antagonists of toll-like receptor (TLR) 7, TLR8 or TLR9. Methods are disclosed for identifying agonists and antagonists of TLR7, TLR8 or TLR9 using mutant TLR proteins containing deletions in one or more extracellular leucine rich regions (LRRs). Such agonists and antagonists have utility in the prevention, treatment and/or cure of various diseases and conditions, including cancer, virus infection, allergy, asthma, and chronic obstructive pulmonary disease (COPD).
    Type: Application
    Filed: March 23, 2006
    Publication date: November 30, 2006
    Inventors: Jaromir Vlach, Uzma Hasan, Sandra Dollet