Patents by Inventor Sandra E. DUNN

Sandra E. DUNN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRYSTALLINE FORMS OF AN RSK INHIBITOR
    Publication number: 20220112193
    Abstract: Described herein are crystalline forms of (R)—N-(1-(4-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl-6-oxo-6,7,8,9-tetrahydropyrido[3?,2?:4,5]-pyrrolo[1,2-a]pyrazine-2-carboxamide hydrochloride and solvates thereof; pharmaceutical compositions and use thereof in treating cancer such as breast cancer, prostate cancer, lung cancer, brain cancer, skin cancer, bone cancer, ovarian cancer, multiple myeloma and leukemia.
    Type: Application
    Filed: February 10, 2020
    Publication date: April 14, 2022
    Inventors: Richard WINNIKE, Elaine MCPHERSON, Erik FLAHIVE, Sandra E. DUNN, Jonathan LOUGHREY
  • CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS
    Publication number: 20210186961
    Abstract: Described herein are carboxamide derivatives that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity.
    Type: Application
    Filed: June 30, 2020
    Publication date: June 24, 2021
    Inventors: Sandra E. DUNN, Aarthi JAYANTHAN, Jaipal Reddy NAGIREDDY, Subhash ANNEDI, John H. VAN DRIE, Timothy S. DAYNARD, My-my HUYNH
  • Carboxamide derivatives useful as rsk inhibitors
    Patent number: 10758530
    Abstract: Described herein are carboxamide derivatives that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity. Such carboxamide derivatives form bicyclic and tricyclic ring systems and the disease or condition associated with RSK activity in a mammal is cancer.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: September 1, 2020
    Assignee: PHOENIX MOLECULAR DESIGNS
    Inventors: Sandra E. Dunn, Aarthi Jayanthan, Jaipal Reddy Nagireddy, Subhash Annedi, John H. Van Drie, Timothy S. Daynard, My-my Huynh
  • CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS
    Publication number: 20190134029
    Abstract: Described herein are carboxamide derivatives that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity. Such carboxamide derivatives form bicyclic and tricyclic ring systems and the disease or condition associated with RSK activity in a mammal is cancer.
    Type: Application
    Filed: February 17, 2017
    Publication date: May 9, 2019
    Inventors: Sandra E. DUNN, Aarthi JAYANTHAN, Jaipal Reddy NAGIREDDY, Subhash ANNEDI, John H. VAN DRIE, Timothy S. DAYNARD, My-my HUYNH
  • Substituted tetrahydropyrido[3?,2?:4,5]pyrrolo[1,2-?]pyrazine-2-carboxamides as RSK inhibitors
    Patent number: 10081632
    Abstract: Described herein are carboxamide derivatives of Formula (II) that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity: wherein R2, R4a, R4b, R11, R12, and n are defined in the specification.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: September 25, 2018
    Assignee: PHOENIX MOLECULAR DESIGNS
    Inventors: Sandra E. Dunn, Aarthi Jayanthan, Jaipal Reddy Nagireddy, Subhash Annedi, John H. Van Drie, Timothy S. Daynard, My-my Huynh
  • CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS
    Publication number: 20170327501
    Abstract: Described herein are carboxamide derivatives that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity.
    Type: Application
    Filed: July 31, 2017
    Publication date: November 16, 2017
    Inventors: Sandra E. DUNN, Aarthi JAYANTHAN, Jaipal Reddy NAGIREDDY, Subhash ANNEDI, John H. VAN DRIE, Timothy S. DAYNARD, My-my HUYNH
  • Substituted tetrahydropyrido[3?,2?:4,5]pyrrolo[1,2-a]pyrazine-2-carboxamides as RSK inhibitors
    Patent number: 9771366
    Abstract: Described herein are carboxamide derivatives of Formula (II) that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity: wherein R2, R4a, R4b, R11, R12, and n are defined in the specification.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: September 26, 2017
    Assignee: PHOENIX MOLECULAR DESIGN
    Inventors: Sandra E. Dunn, Aarthi Jayanthan, Jaipal Reddy Nagireddy, Subhash Annedi, John H. Van Drie, Timothy S. Daynard, My-my Huynh
  • TETRAHYDROPYRIDO[3',2':4,5]PYRROLO[1,2-a]PYRAZINE-2-CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS
    Publication number: 20170240549
    Abstract: Described herein are carboxamide derivatives that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity.
    Type: Application
    Filed: February 17, 2017
    Publication date: August 24, 2017
    Inventors: Sandra E. DUNN, Aarthi JAYANTHAN, Jaipal Reddy NAGIREDDY, Subhash ANNEDI, John H. VAN DRIE, Timothy S. DAYNARD, My-my HUYNH