Patents by Inventor Sandra E. Pike

Sandra E. Pike has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vasostatin as marrow protectant
    Patent number: 7812117
    Abstract: Specific fragments of vasostatin are disclosed. These fragments are of use in methods of stimulating the proliferation or survival of a hematopoietic cell exposed to a chemotherapeutic agent or irradiation. Methods of stimulating the proliferation or survival of a hematopoietic cell using these fragments are also disclosed. In one embodiment, methods are disclosed for stimulating the growth or survival of a hematopoietic stem cell with a fragment of vasostatin, in the presence of a growth factor.
    Type: Grant
    Filed: August 26, 2008
    Date of Patent: October 12, 2010
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Giovanna Tosato, Sandra E. Pike, Lei Yao
  • VASOSTATIN AS MARROW PROTECTANT
    Publication number: 20090149380
    Abstract: Specific fragments of vasostatin are disclosed. These fragments are of use in methods of stimulating the proliferation or survival of a hematopoietic cell exposed to a chemotherapeutic agent or irradiation. Methods of stimulating the proliferation or survival of a hematopoietic cell using these fragments are also disclosed. In one embodiment, methods are disclosed for stimulating the growth or survival of a hematopoietic stem cell with a fragment of vasostatin, in the presence of a growth factor.
    Type: Application
    Filed: August 26, 2008
    Publication date: June 11, 2009
    Inventors: Giovanna Tosato, Sandra E. Pike, Lei Yao
  • Use of calreticulin and calreticulin fragments to inhibit endothelial cell growth and angiogenesis, and suppress tumor growth
    Patent number: 7488711
    Abstract: Methods for inhibiting endothelial cell growth and angiogenesis, and suppressing tumor growth using calreticulin, fragments of calreticulin and variants of calreticulin are provided. Such methods are useful for the treatment of cancer and diseases associated with unwanted angiogenesis, for example chronic retinal detachment.
    Type: Grant
    Filed: January 20, 2005
    Date of Patent: February 10, 2009
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Giovanna Tosato, Sandra E. Pike, Lei Yao
  • Vasostatin as marrow protectant
    Patent number: 7432236
    Abstract: Specific fragments of vasostatin are disclosed. Also disclosed is a method of stimulating the proliferation or survival of a hematopoietic cell exposed to a chemotherapeutic agent or irradiation using these fragments. A method of stimulating the proliferation or survival of a hematopoietic cell is also disclosed. In one embodiment, the method is disclosed for stimulating the growth or survival of a hematopoietic stem cell with a fragment of vasostatin, in the presence of a growth factor.
    Type: Grant
    Filed: April 1, 2003
    Date of Patent: October 7, 2008
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Giovanna Tosato, Sandra E. Pike, Lei Yao
  • Use of calreticulin and calreticulin fragments to inhibit endothelial cell growth and angiogenesis, and suppress tumor growth
    Patent number: 6867180
    Abstract: Methods for inhibiting endothelial cell growth and angiogenesis, and suppressing tumor growth using calreticulin, fragments of calreticulin and variants of calreticulin are provided. Such methods are useful for the treatment of cancer and diseases associated with unwanted angiogenesis, for example chronic retinal detachment.
    Type: Grant
    Filed: October 5, 1999
    Date of Patent: March 15, 2005
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Giovanna Tosato, Sandra E. Pike, Lei Yao
  • Vasostatin as marrow protectant
    Publication number: 20030216299
    Abstract: Specific fragments of vasostatin are disclosed. Also disclosed is a method of stimulating the proliferation or survival of a hematopoietic cell exposed to a chemotherapeutic agent or irradiation using these fragments. A method of stimulating the proliferation or survival of a hematopoietic cell is also disclosed. In one embodiment, the method is disclosed for stimulating the growth or survival of a hematopoietic stem cell with a fragment of vasostatin, in the presence of a growth factor.
    Type: Application
    Filed: April 1, 2003
    Publication date: November 20, 2003
    Applicants: The Government of the United States of America as, represented by the Secretary of Health and Human Services
    Inventors: Giovanna Tosato, Sandra E. Pike, Lei Yao
  • Vasostatin as marrow protectant
    Patent number: 6596690
    Abstract: Specific fragments of vasostatin are disclosed. Also disclosed is a method of stimulating the proliferation or survival of a hematopoietic cell exposed to a chemotherapeutic agent or irradiation using these fragments. A method of stimulating the proliferation or survival of a hematopoietic cell is also disclosed. In one embodiment, the method is disclosed for stimulating the growth or survival of a hematopoietic stem cell with a fragment of vasostatin, in the presence of a growth factor.
    Type: Grant
    Filed: April 6, 2001
    Date of Patent: July 22, 2003
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Giovanna Tosato, Sandra E. Pike, Lei Yao
  • Vasostatin as marrow protectant
    Publication number: 20030078198
    Abstract: Specific fragments of vasostatin are disclosed. Also disclosed is a method of stimulating the proliferation or survival of a hematopoietic cell exposed to a chemotherapeutic agent or irradiation using these fragments. A method of stimulating the proliferation or survival of a hematopoietic cell is also disclosed. In one embodiment, the method is disclosed for stimulating the growth or survival of a hematopoietic stem cell with a fragment of vasostatin, in the presence of a growth factor.
    Type: Application
    Filed: April 6, 2001
    Publication date: April 24, 2003
    Applicant: The Government of the United States of America
    Inventors: Giovanna Tosato, Sandra E. Pike, Lei Yao