Patents by Inventor Sandra J. Degen

Sandra J. Degen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the treatment of hepatic disorders
    Patent number: 7235523
    Abstract: The present invention relates to the prevention and treatment of injury and diseases to the liver, biliary tract, bile ducts, gall bladder and related hepatobiliary system. Specifically, the present invention relates to methods for decreasing the action of the RON receptor tyrosine kinase in liver physiology. More specifically, the present invention relates to the use of analogs and antagonists and antibodies for inhibiting the action of the RON receptor tyrosine kinase for the prevention and treatment of liver injury or damage in acute and chronic clinical conditions.
    Type: Grant
    Filed: April 15, 2002
    Date of Patent: June 26, 2007
    Assignee: Children's Hospital Medical Center
    Inventors: Susan E. Waltz, Mike A. Leonis, Sandra J. Degen
  • Methods for the treatment of hepatic disorders
    Publication number: 20030073656
    Abstract: The present invention relates to the prevention and treatment of injury and diseases to the liver, biliary tract, bile ducts, gall bladder and related hepatobiliary system. Specifically, the present invention relates to methods for decreasing the action of the RON receptor tyrosine kinase in liver physiology. More specifically, the present invention relates to the use of analogs and antagonists and antibodies for inhibiting the action of the RON receptor tyrosine kinase for the prevention and treatment of liver injury or damage in acute and chronic clinical conditions.
    Type: Application
    Filed: April 15, 2002
    Publication date: April 17, 2003
    Applicant: Children's Hospital Medical Center
    Inventors: Susan E. Waltz, Mike A. Leonis, Sandra J. Degen
  • Gene for a growth factor and its cDNA and protein
    Patent number: 5606029
    Abstract: A growth factor protein similar in structure and function to hepatocyte growth factor has been discovered along with the DNA and cDNA coding for this in both the mouse and human. The DNA includes 18 exons and is homologous to DNA at the D3F15S2 locus on human chromosome 3; a region predicted to code for one or more tumor suppressor genes.
    Type: Grant
    Filed: January 18, 1994
    Date of Patent: February 25, 1997
    Assignee: Children's Hospital Medical Center
    Inventor: Sandra J. Degen
  • Gene encoding for a L5/3 growth factor and its CDNA
    Patent number: 5315000
    Abstract: A growth factor protein similar in structure and function to hepatocyte growth factor has been discovered along with the DNA and cDNA coding for this in both the mouse and human. The DNA includes 18 exons and is homologous to DNA at the D3F15S2 locus on human chromosome 3; a region predicted to code for one or more tumor suppressor genes.
    Type: Grant
    Filed: May 14, 1992
    Date of Patent: May 24, 1994
    Assignee: Children's Hospital Medical Center
    Inventor: Sandra J. Degen