Patents by Inventor Sandra J. Gendler

Sandra J. Gendler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND MATERIALS FOR EXPANDING ANTIGEN-SPECIFIC T CELLS IN CULTURE
    Publication number: 20230357718
    Abstract: This document provides methods and materials for expanding antigen-specific T cells (e.g., antigen-specific CD4+ T cells and/or antigen-specific CD8+ T cells) in culture. For example, methods and materials for performing a polyclonal stimulation step for a particular duration (e.g., from about 1 hour to about 48 hours) to increase the expansion of T cells having a desired antigen specificity are provided.
    Type: Application
    Filed: July 13, 2023
    Publication date: November 9, 2023
    Applicants: Mayo Foundation for Medical Education and Research, University of Washington
    Inventors: Peter A. Cohen, JR., Sandra J. Gendler, Latha B. Pathangey, Dustin B. McCurry, Jessica E. Gorman, Mary L. Disis
  • Methods and materials for expanding antigen-specific T cells in culture
    Patent number: 11739296
    Abstract: This document provides methods and materials for expanding antigen-specific T cells (e.g., antigen-specific CD4+ T cells and/or antigen-specific CD8+ T cells) in culture. For example, methods and materials for performing a polyclonal stimulation step for a particular duration (e.g., from about 1 hour to about 48 hours) to increase the expansion of T cells having a desired antigen specificity are provided.
    Type: Grant
    Filed: April 14, 2020
    Date of Patent: August 29, 2023
    Assignees: Mayo Foundation for Medical Education and Research, University of Washington
    Inventors: Peter A. Cohen, Sandra J. Gendler, Latha B. Pathangey, Dustin B. McCurry, Jessica E. Gorman, Mary L. Disis
  • METHODS AND VACCINES FOR INDUCING IMMUNE RESPONSES TO MULTIPLE DIFFERENT MHC MOLECULES
    Publication number: 20230098624
    Abstract: This document provides methods and materials relating to isolated polypeptides, polypeptide preparations, vaccine preparations (e.g., anti-cancer vaccine preparations), and methods for vaccinating mammals. For example, polypeptides (e.g., CMV, MUC1, HER2, Mesothelin (MESO), TRAG-3, or CALR polypeptides) having the ability to be processed into different polypeptides such that the processed polypeptides as a group are capable of being presented by different MHC molecules present in a particular mammalian population are provided.
    Type: Application
    Filed: August 24, 2022
    Publication date: March 30, 2023
    Inventors: Dustin B. McCurry, Peter A. Cohen, Latha B. Pathangey, Sandra J. Gendler, Mary L. Disis
  • Methods and vaccines for inducing immune responses to multiple different MHC molecules
    Patent number: 11464839
    Abstract: This document provides methods and materials relating to isolated polypeptides, polypeptide preparations, vaccine preparations (e.g., anti-cancer vaccine preparations), and methods for vaccinating mammals. For example, polypeptides (e.g., CMV, MUC1, HER2, Mesothelin (MESO), TRAG-3, or CALR polypeptides) having the ability to be processed into different polypeptides such that the processed polypeptides as a group are capable of being presented by different MHC molecules present in a particular mammalian population are provided.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: October 11, 2022
    Assignees: Mayo Foundation for Medical Education and Research, University of Washington
    Inventors: Dustin B. McCurry, Peter A. Cohen, Latha B. Pathangey, Sandra J. Gendler, Mary L. Disis
  • METHODS AND MATERIALS FOR EXPANDING ANTIGEN-SPECIFIC T CELLS IN CULTURE
    Publication number: 20200248140
    Abstract: This document provides methods and materials for expanding antigen-specific T cells (e.g., antigen-specific CD4+ T cells and/or antigen-specific CD8+ T cells) in culture. For example, methods and materials for performing a polyclonal stimulation step for a particular duration (e.g., from about 1 hour to about 48 hours) to increase the expansion of T cells having a desired antigen specificity are provided.
    Type: Application
    Filed: April 14, 2020
    Publication date: August 6, 2020
    Inventors: Peter A. Cohen, Sandra J. Gendler, Latha B. Pathangey, Dustin B. McCurry, Jessica E. Gorman, Mary L. Disis
  • Methods and materials for expanding antigen-specific T cells in culture
    Patent number: 10647961
    Abstract: This document provides methods and materials for expanding antigen-specific T cells (e.g., antigen-specific CD4+ T cells and/or antigen-specific CD8+ T cells) in culture. For example, methods and materials for performing a polyclonal stimulation step for a particular duration (e.g., from about 1 hour to about 48 hours) to increase the expansion of T cells having a desired antigen specificity are provided.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: May 12, 2020
    Assignees: Mayo Foundation for Medical Education and Research, University of Washington
    Inventors: Peter A. Cohen, Sandra J. Gendler, Latha B. Pathangey, Dustin B. McCurry, Jessica E. Gorman, Mary L. Disis
  • METHODS AND VACCINES FOR INDUCING IMMUNE RESPONSES TO MULTIPLE DIFFERENT MHC MOLECULES
    Publication number: 20190000948
    Abstract: This document provides methods and materials relating to isolated polypeptides, polypeptide preparations, vaccine preparations (e.g., anti-cancer vaccine preparations), and methods for vaccinating mammals. For example, polypeptides (e.g., CMV, MUC1, HER2, Mesothelin (MESO), TRAG-3, or CALR polypeptides) having the ability to be processed into different polypeptides such that the processed polypeptides as a group are capable of being presented by different MHC molecules present in a particular mammalian population are provided.
    Type: Application
    Filed: December 2, 2016
    Publication date: January 3, 2019
    Inventors: Dustin B. McCurry, Peter A. Cohen, Latha B. Pathangey, Sandra J. Gendler, Mary L. Disis
  • Blocking IL-9 signaling in conjunction with chemotherapy to treat cancer
    Patent number: 10166292
    Abstract: This document provides methods and materials related to using inhibitors of IL-9 signaling in conjunction with chemotherapy to treat cancer (e.g., solid tumors). For example, methods and materials for using inhibitors of IL-9 signaling (e.g., anti-IL9 antibody preparations) in conjunction with chemotherapy to treat cancer (e.g., solid tumors such as breast cancer tumors or colon cancer tumors) or to reduce the growth rate of cancer (e.g., solid tumors such as breast cancer tumors or colon cancer tumors) within a mammal are provided.
    Type: Grant
    Filed: October 30, 2017
    Date of Patent: January 1, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Dominique B. Hoelzinger, Sandra J. Gendler, Peter A. Cohen, Ana L. Dominguez, Shannon E. Smith, Joseph Lustgarten
  • METHODS AND MATERIALS FOR EXPANDING ANTIGEN-SPECIFIC T CELLS IN CULTURE
    Publication number: 20180245042
    Abstract: This document provides methods and materials for expanding antigen-specific T cells (e.g., antigen-specific CD4+ T cells and/or antigen-specific CD8+ T cells) in culture. For example, methods and materials for performing a polyclonal stimulation step for a particular duration (e.g., from about 1 hour to about 48 hours) to increase the expansion of T cells having a desired antigen specificity are provided.
    Type: Application
    Filed: August 12, 2016
    Publication date: August 30, 2018
    Inventors: Peter A. Cohen, Sandra J. Gendler, Latha B. Pathangey, Dustin B. McCurry, Jessica E. Gorman, Mary L. Disis
  • BLOCKING IL-9 SIGNALING IN CONJUNCTION WITH CHEMOTHERAPY TO TREAT CANCER
    Publication number: 20180153994
    Abstract: This document provides methods and materials related to using inhibitors of IL-9 signaling in conjunction with chemotherapy to treat cancer (e.g., solid tumors). For example, methods and materials for using inhibitors of IL-9 signaling (e.g., anti-IL9 antibody preparations) in conjunction with chemotherapy to treat cancer (e.g., solid tumors such as breast cancer tumors or colon cancer tumors) or to reduce the growth rate of cancer (e.g., solid tumors such as breast cancer tumors or colon cancer tumors) within a mammal are provided.
    Type: Application
    Filed: October 30, 2017
    Publication date: June 7, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Dominique B. Hoelzinger, Sandra J. Gendler, Peter A. Cohen, Ana L. Dominguez, Shannon E. Smith, Joseph Lustgarten
  • Blocking IL-9 signaling in conjunction with chemotherapy to treat cancer
    Patent number: 9833512
    Abstract: This document provides methods and materials related to using inhibitors of IL-9 signaling in conjunction with chemotherapy to treat cancer (e.g., solid tumors). For example, methods and materials for using inhibitors of IL-9 signaling (e.g., anti-IL9 antibody preparations) in conjunction with chemotherapy to treat cancer (e.g., solid tumors such as breast cancer tumors or colon cancer tumors) or to reduce the growth rate of cancer (e.g., solid tumors such as breast cancer tumors or colon cancer tumors) within a mammal are provided.
    Type: Grant
    Filed: April 9, 2015
    Date of Patent: December 5, 2017
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Dominique B. Hoelzinger, Sandra J. Gendler, Peter A. Cohen, Ana L. Dominguez, Shannon E. Smith, Joseph Lustgarten
  • BLOCKING IL-9 SIGNALING IN CONJUNCTION WITH CHEMOTHERAPY TO TREAT CANCER
    Publication number: 20150343057
    Abstract: This document provides methods and materials related to using inhibitors of IL-9 signaling in conjunction with chemotherapy to treat cancer (e.g., solid tumors). For example, methods and materials for using inhibitors of IL-9 signaling (e.g., anti-IL9 antibody preparations) in conjunction with chemotherapy to treat cancer (e.g., solid tumors such as breast cancer tumors or colon cancer tumors) or to reduce the growth rate of cancer (e.g., solid tumors such as breast cancer tumors or colon cancer tumors) within a mammal are provided.
    Type: Application
    Filed: April 9, 2015
    Publication date: December 3, 2015
    Inventors: Dominique B. Hoelzinger, Sandra J. Gendler, Peter A. Cohen, Ana L. Dominguez, Shannon E. Smith, Joseph Lustgarten
  • IMMUNOGENIC VACCINE
    Publication number: 20150299290
    Abstract: A glycolipopeptide comprising a carbohydrate component, a lipid component, and a MUC1 peptide component that induces both a humoral and a cellular immune response for use as a therapeutic or prophylactic vaccine.
    Type: Application
    Filed: April 24, 2015
    Publication date: October 22, 2015
    Inventors: GEERT-JAN BOONS, MARGARETHA WOLFERT, SANDRA J. GENDLER, VANI LAKSHMINARAYANAN, PETER A. COHEN
  • IMMUNOGENIC VACCINE
    Publication number: 20130236486
    Abstract: A glycolipopeptide comprising a carbohydrate component, a lipid component, and a MUC1 peptide component that induces both a humoral and a cellular immune response for use as a therapeutic or prophylactic vaccine.
    Type: Application
    Filed: June 10, 2011
    Publication date: September 12, 2013
    Applicants: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, UNIVERSITY OF GEORGIA RESEARCH FOUNDATION,INC
    Inventors: Geert-Jan Boons, Margaretha Wolfert, Sandra J. Gendler, Vani Lakshminarayanan, Peter A. Cohen