Abstract: The methods and devices for delivering therapeutic agents to abdominal aortic or thoracic aortic aneurysms provide a coated stent graft and methods of using the same. The coated stent graft system 100 comprises a support 20 and graft material 40 attached to the support 20, with a coating 30, 35 including a therapeutic agent disposed on the support 20 and/or the graft material 40. The coated stent graft system 600 can also include a stent graft portion 605 with an agent delivery portion 655 disposed about the stent graft portion 605 and including a therapeutic agent. A stent graft drug delivery system can include an endovascular catheter 710 having a coated region 730 with a therapeutic agent, and a stent graft 705 disposed on the endovascular catheter 710. The endovascular catheter 710 can have a balloon for releasing the therapeutic agent. The therapeutic agent can be injected by endovascular catheter on carrier particles.