Patents by Inventor Sandra Li

Sandra Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMANIZED ANTI-IL-1R3 ANTIBODY AND METHODS OF USE
    Publication number: 20240101691
    Abstract: An antibody that specifically binds to IL-1R3, comprising an antibody heavy chain amino acid sequence of SEQ ID NO: 1 and a light chain amino acid sequence of SEQ ID NO: 2. A pharmaceutical composition is provided comprising the said antibody and a pharmaceutically acceptable diluent, carrier or excipient. Also said antibody for use in treating a disease or disorder in a subject in need thereof. The disease or disorder may be an autoimmune or autoinflammatory disease or disorder.
    Type: Application
    Filed: September 21, 2023
    Publication date: March 28, 2024
    Inventors: Michael COOLBAUGH, Christian LANGE, Ziyu LI, Björn STEINMANN, Hanno SJUTS, Sandra WEIL
  • Methods for inhibiting tumor growth or treating cancer by administering an immunoglobulin single variable domain that binds glucocorticoid-induced TNFR family-related receptor (GITR)
    Patent number: 11919966
    Abstract: The present invention relates to immunoglobulin single variable domains that bind GITR and more in particular to polypeptides that comprise or essentially consist of one or more such immunoglobulin single variable domains; to nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the polypeptides of the present invention enhance the biological activity of GITR.
    Type: Grant
    Filed: May 14, 2021
    Date of Patent: March 5, 2024
    Assignee: Ablynx N.V.
    Inventors: Pieter Deschaght, Sandra Li, Veerle Snoeck, Jan Pype
  • POLYPEPTIDES THAT BIND GLUCOCORTICOID-INDUCED TNFR FAMILY-RELATED RECEPTOR (GITR)
    Publication number: 20220411521
    Abstract: The present invention relates to immunoglobulin single variable domains that bind GITR and more in particular to polypeptides that comprise or essentially consist of one or more such immunoglobulin single variable domains; to nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the polypeptides of the present invention enhance the biological activity of GITR.
    Type: Application
    Filed: May 14, 2021
    Publication date: December 29, 2022
    Applicant: Ablynx N.V.
    Inventors: Pieter Deschaght, Sandra Li, Veerle Snoeck, Jan Pype
  • Polypeptides that bind glucocorticoid-induced TNFR family-related receptor (GITR)
    Patent number: 11059899
    Abstract: The present invention relates to immunoglobulin single variable domains that bind GITR and more in particular to polypeptides that comprise or essentially consist of one or more such immunoglobulin single variable domains; to nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the polypeptides of the present invention enhance the biological activity of GITR.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: July 13, 2021
    Assignee: Ablynx N.V.
    Inventors: Pieter Deschaght, Sandra Li, Veerle Snoeck, Jan Pype