Patents by Inventor Sandra Li

Sandra Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS TARGETING PD-1
    Publication number: 20260274953
    Abstract: The present technology provides polypeptides that binds to PD-1. The present technology also provides nucleic acids, vectors and compositions. Also provided are multispecific binding proteins (e.g., bispecific binding proteins) that targeting a TNF receptor superfamily (TNFRSF) receptor (e.g., GITR) and an immune checkpoint protein (e.g., PD-1).
    Type: Application
    Filed: December 19, 2025
    Publication date: September 17, 2026
    Inventors: Jérémy Baudhuin, Christian Beil, Thomas Bertrand, Magdalena Bukowska, Christian Lange, Sandra Li, Sevim Özgür Brüderle, Natalia Sarmiento, Ingrid Sassoon, Sandra Weil
  • Methods for inhibiting tumor growth or treating cancer by administering an immunoglobulin single variable domain that binds glucocorticoid-induced TNFR family-related receptor (GITR)
    Patent number: 11919966
    Abstract: The present invention relates to immunoglobulin single variable domains that bind GITR and more in particular to polypeptides that comprise or essentially consist of one or more such immunoglobulin single variable domains; to nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the polypeptides of the present invention enhance the biological activity of GITR.
    Type: Grant
    Filed: May 14, 2021
    Date of Patent: March 5, 2024
    Assignee: Ablynx N.V.
    Inventors: Pieter Deschaght, Sandra Li, Veerle Snoeck, Jan Pype
  • POLYPEPTIDES THAT BIND GLUCOCORTICOID-INDUCED TNFR FAMILY-RELATED RECEPTOR (GITR)
    Publication number: 20220411521
    Abstract: The present invention relates to immunoglobulin single variable domains that bind GITR and more in particular to polypeptides that comprise or essentially consist of one or more such immunoglobulin single variable domains; to nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the polypeptides of the present invention enhance the biological activity of GITR.
    Type: Application
    Filed: May 14, 2021
    Publication date: December 29, 2022
    Applicant: Ablynx N.V.
    Inventors: Pieter Deschaght, Sandra Li, Veerle Snoeck, Jan Pype
  • Polypeptides that bind glucocorticoid-induced TNFR family-related receptor (GITR)
    Patent number: 11059899
    Abstract: The present invention relates to immunoglobulin single variable domains that bind GITR and more in particular to polypeptides that comprise or essentially consist of one or more such immunoglobulin single variable domains; to nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the polypeptides of the present invention enhance the biological activity of GITR.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: July 13, 2021
    Assignee: Ablynx N.V.
    Inventors: Pieter Deschaght, Sandra Li, Veerle Snoeck, Jan Pype
  • Display screen with an animated graphical user interface
    Patent number: D1081696
    Type: Grant
    Filed: December 28, 2023
    Date of Patent: July 1, 2025
    Assignee: Northspyre, Inc.
    Inventors: William Sankey, John Fassold, Hayley Yeager, Eileen Xia, Tiffany Chin, Sandra Li