Patents by Inventor Sandra M. Zurawski

Sandra M. Zurawski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated Mammalian Monocyte Cell Genes; Related Reagents
    Publication number: 20140141444
    Abstract: DNA clones encoding a receptor in the Ig superfamily and a related soluble variant have been isolated from a human monocyte library. The invention provides receptor polypeptides, nucleic acids encoding them, expression vectors, and transformed cells for recombinant production of the polypeptides.
    Type: Application
    Filed: January 28, 2014
    Publication date: May 22, 2014
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Gosse Jan Adema, Linde Meyaard, Daniel M. Gorman, Terrill K. McClanahan, Sandra M. Zurawski, Gerard Zurawski, Lewis L. Lanier, Joseph H. Phillips
  • Isolated Mammalian Monocyte Cell Genes; Related Reagents
    Publication number: 20140141445
    Abstract: DNA clones encoding a receptor in the Ig superfamily and a related soluble variant have been isolated from a human monocyte library. The invention provides receptor polypeptides, nucleic acids encoding them, expression vectors, and transformed cells for recombinant production of the polypeptides.
    Type: Application
    Filed: January 28, 2014
    Publication date: May 22, 2014
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Gosse Jan Adema, Linde Meyaard, Daniel M. Gorman, Terrill K. McClanahan, Sandra M. Zurawski, Gerard Zurawski, Lewis L. Lanier, Joseph H. Phillips
  • ISOLATED MAMMALIAN MONOCYTE CELL GENES; RELATED REAGENTS
    Publication number: 20130034561
    Abstract: Nucleic acids encoding various monocyte cell proteins from a primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Application
    Filed: October 12, 2012
    Publication date: February 7, 2013
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Gosse Jan Adema, Linde Meyaard, Daniel M. Gorman, Terrill K. McClanahan, Sandra M. Zurawski, Gerard Zurawski, Lewis L. Lanier, Joseph H. Phillips
  • Uses of IL-174 Antagonists for Inhibiting A Th2 Immune Response
    Publication number: 20120141411
    Abstract: Agonists or antagonists of cytokine designated IL-174, and various methods of their use are provided. In particular, the methods make use of facts that many activities of the IL-174 cytokine are described.
    Type: Application
    Filed: January 25, 2012
    Publication date: June 7, 2012
    Applicant: Schering Corporation
    Inventors: Stephen D. Hurst, Sandra M. Zurawski, Donna M. Rennick
  • ISOLATED MAMMALIAN MONOCYTE CELL GENES; RELATED REAGENTS
    Publication number: 20120020990
    Abstract: Nucleic acids encoding various monocyte cell proteins from a primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Application
    Filed: July 25, 2011
    Publication date: January 26, 2012
    Applicant: Schering Corporation
    Inventors: Gosse Jan Adema, Linde Meyaard, Daniel M. Gorman, Terrill K. McClanahan, Sandra M. Zurawski, Gerard Zurawski, Lewis L. Lanier, Joseph H. Phillips, JR.
  • USES OF IL-174 ANTAGONISTS FOR INHIBITING A Th2 IMMUNE RESPONSE
    Publication number: 20110223130
    Abstract: Agonists or antagonists of cytokine designated IL-174, and various methods of their use are provided. In particular, the methods make use of facts that many activities of the IL-174 cytokine are described.
    Type: Application
    Filed: April 20, 2011
    Publication date: September 15, 2011
    Applicant: Schering Corporation
    Inventors: STEPHEN D. HURST, Sandra M. Zurawski, Donna M. Rennick
  • ISOLATED MAMMALIAN MONOCYTE CELL GENES; RELATED REAGENTS
    Publication number: 20100209907
    Abstract: Nucleic acids encoding various monocyte cell proteins from a primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Application
    Filed: November 5, 2008
    Publication date: August 19, 2010
    Inventors: Gosse Jan Adema, Linde Meyaard, Daniel M. Gorman, Terrill K. McClanahan, Sandra M. Zurawski, Gerard Zurawski, Lewis L. Lanier, Joseph H. Phillips, JR.
  • USES OF IL-174 ANTAGONISTS FOR INHIBITING A TH2 IMMUNE RESPONSE
    Publication number: 20100136020
    Abstract: Agonists or antagonists of cytokine designated IL-174, and various methods of their use are provided. In particular, the methods make use of facts that many activities of the IL-174 cytokine are described.
    Type: Application
    Filed: November 6, 2009
    Publication date: June 3, 2010
    Inventors: Stephen D. Hurst, Sandra M. Zurawski, Donna M. Rennick
  • USES OF IL-174 ANTAGONISTS FOR INHIBITING A Th2 IMMUNE RESPONSE
    Publication number: 20090263401
    Abstract: Agonists or antagonists of cytokine designated IL-174, and various methods of their use are provided. In particular, the methods make use of facts that many activities of the IL-174 cytokine are described.
    Type: Application
    Filed: December 17, 2007
    Publication date: October 22, 2009
    Applicant: Schering Corporation
    Inventors: Stephen D. Hurst, Sandra M. Zurawski, Donna M. Rennick
  • Uses of IL-174 for treating helminth infections
    Patent number: 7357924
    Abstract: Use of the cytokine designated IL-174 to treat infectious diseases such as helminth infections.
    Type: Grant
    Filed: November 10, 2003
    Date of Patent: April 15, 2008
    Assignee: Schering Corporation
    Inventors: Stephen D. Hurst, Sandra M. Zurawski, Donna M. Rennick
  • Isolated mammalian monocyte cell genes; related reagents
    Publication number: 20040143858
    Abstract: Nucleic acids encoding various monocyte cell proteins from a primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Application
    Filed: February 11, 2004
    Publication date: July 22, 2004
    Applicant: Schering Corporation, a New Jersey corporation
    Inventors: Gosse Jan Adema, Linde Meyaard, Daniel M. Gorman, Terrill K. McClanahan, Sandra M. Zurawski, Gerard Zurawski, Lewis L. Lanier, Joseph H. Phillips
  • Cytokine uses; compositions; methods
    Publication number: 20040076608
    Abstract: Agonists or antagonists of cytokine designated IL-174, and various methods of their use are provided. In particular, the methods make use of facts that many activities of the IL-174 cytokine are described.
    Type: Application
    Filed: November 10, 2003
    Publication date: April 22, 2004
    Inventors: Stephen D. Hurst, Sandra M. Zurawski, Donna M. Rennick
  • Methods of modulating IL-174 response
    Patent number: 6676939
    Abstract: Agonists or antagonists of cytokine designated IL-174, and various methods of their use are provided. In particular, the methods make use of facts that many activities of the IL-174 cytokine are described.
    Type: Grant
    Filed: April 17, 2001
    Date of Patent: January 13, 2004
    Assignee: Schering Corporation
    Inventors: Stephen D. Hurst, Sandra M. Zurawski, Donna M. Rennick
  • METHODS OF MODULATING IL- 174 RESPONSE
    Publication number: 20030165460
    Abstract: Agonists or antagonists of cytokine designated IL-174, and various methods of their use are provided. In particular, the methods make use of facts that many activities of the IL-174 cytokine are described.
    Type: Application
    Filed: April 17, 2001
    Publication date: September 4, 2003
    Inventors: Stephen D. Hurst, Sandra M. Zurawski, Donna M. Rennick
  • Isolated mammalian monocyte cell genes; related reagents
    Publication number: 20030105303
    Abstract: Nucleic acids encoding various monocyte cell proteins from a primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Application
    Filed: November 8, 2002
    Publication date: June 5, 2003
    Applicant: Schering Corporation, a New Jersey corporation
    Inventors: Gosse Jan Adema, Linde Meyaard, Daniel M. Gorman, Terrill K. McClanahan, Sandra M. Zurawski, Gerard Zurawski, Lewis L. Lanier, Joseph H. Phillips
  • Antibodies that specifically bind DNAX leukocyte associated immunoglobulin-like receptor
    Patent number: 6479638
    Abstract: Nucleic acids encoding various monocyte cell proteins from a primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using reagents relating to nucleic acids encoding monocyte cell proteins, and diagnostic kits, are also provided.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: November 12, 2002
    Assignee: Schering Corporation
    Inventors: Gosse Jan Adema, Linde Meyaard, Daniel M. Gorman, Terrill K. McClanahan, Sandra M. Zurawski, Gerard Zurawski, Lewis L. Lanier, Joseph H. Phillips, Jr.
  • Muteins of mammalian cytokine interleukin-13
    Patent number: 5696234
    Abstract: Methods for screening for partial agonists and for antagonists of mammalian cytokines. Particular positions of natural cytokines are identified as critical in providing these receptor mediated properties. Specific embodiments demonstrate properties of variations at these positions.
    Type: Grant
    Filed: August 1, 1994
    Date of Patent: December 9, 1997
    Assignee: Schering Corporation
    Inventors: Sandra M. Zurawski, Gerard Zurawski
  • T cell activation markers
    Patent number: 5136022
    Abstract: A polypeptide designated H400 and its encoding nucleic acid are provided as markers specific for activated human T cells. Activated T cells are detected immunochemically by monoclonal antibodies specific for H400 or its immunogenic peptides. Activated T cells are also detected by nucleic acid probes directed to messenger RNA encoding the H400 protein.
    Type: Grant
    Filed: January 14, 1991
    Date of Patent: August 4, 1992
    Assignee: Schering Corporation
    Inventors: Keith D. Brown, Timothy R. Mosmann, Gerard Zurawski, Sandra M. Zurawski
  • Truncated human interleukin-a alpha
    Patent number: 5017692
    Abstract: Synthetic human interleukin-1.alpha. genes are provided whose codons are selected from those preferred by bacteria. High expression levels are obtained in an E. coli expression system for both native interleukin-1.alpha. and several mutant interleukin-1.alpha.'s.
    Type: Grant
    Filed: September 4, 1986
    Date of Patent: May 21, 1991
    Assignee: Schering Corporation
    Inventors: Gerard Zurawski, Sandra M. Zurawski