Patents by Inventor Sandra Machado

Sandra Machado has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210154470
    Abstract: Methods of treating acute heart failure in a patient in need thereof. Methods include inserting a therapy delivery device into a pulmonary artery of the patient and applying a therapy signal to autonomic cardiopulmonary fibers surrounding the pulmonary artery. The therapy signal affects heart contractility more than heart rate. Specifically, the application of the therapy signal increases heart contractility and treats the acute heart failure in the patient. The therapy signal can include electrical or chemical modulation.
    Type: Application
    Filed: February 1, 2021
    Publication date: May 27, 2021
    Inventors: Sandra Machado, Marc Penn, Ali R. Rezai
  • Patent number: 10905873
    Abstract: Methods of treating acute heart failure in a patient in need thereof. Methods include inserting a therapy delivery device into a pulmonary artery of the patient and applying a therapy signal to autonomic cardiopulmonary fibers surrounding the pulmonary artery. The therapy signal affects heart contractility more than heart rate. Specifically, the application of the therapy signal increases heart contractility and treats the acute heart failure in the patient. The therapy signal can include electrical or chemical modulation.
    Type: Grant
    Filed: January 25, 2018
    Date of Patent: February 2, 2021
    Assignee: The Cleveland Clinic Foundation
    Inventors: Sandra Machado, Marc Penn, Ali R. Rezai
  • Publication number: 20180147408
    Abstract: Methods of treating acute heart failure in a patient in need thereof. Methods include inserting a therapy delivery device into a pulmonary artery of the patient and applying a therapy signal to autonomic cardiopulmonary fibers surrounding the pulmonary artery. The therapy signal affects heart contractility more than heart rate. Specifically, the application of the therapy signal increases heart contractility and treats the acute heart failure in the patient. The therapy signal can include electrical or chemical modulation.
    Type: Application
    Filed: January 25, 2018
    Publication date: May 31, 2018
    Inventors: Sandra Machado, Marc Penn, Ali R. Rezai
  • Patent number: 9878150
    Abstract: Methods of treating acute heart failure in a patient in need thereof. Methods include inserting a therapy delivery device into a pulmonary artery of the patient and applying a therapy signal to autonomic cardiopulmonary fibers surrounding the pulmonary artery. The therapy signal affects heart contractility more than heart rate. Specifically, the application of the therapy signal increases heart contractility and treats the acute heart failure in the patient. The therapy signal can include electrical or chemical modulation.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: January 30, 2018
    Assignee: The Cleveland Clinic Foundation
    Inventors: Sandra Machado, Marc Penn, Ali R. Rezai
  • Publication number: 20170036014
    Abstract: Methods of treating acute heart failure in a patient in need thereof. Methods include inserting a therapy delivery device into a pulmonary artery of the patient and applying a therapy signal to autonomic cardiopulmonary fibers surrounding the pulmonary artery. The therapy signal affects heart contractility more than heart rate. Specifically, the application of the therapy signal increases heart contractility and treats the acute heart failure in the patient. The therapy signal can include electrical or chemical modulation.
    Type: Application
    Filed: October 25, 2016
    Publication date: February 9, 2017
    Inventors: Sandra Machado, Marc Penn, Ali R. Rezai
  • Patent number: 9480790
    Abstract: Methods of treating acute heart failure in a patient in need thereof. Methods include inserting a therapy delivery device into a pulmonary artery of the patient and applying a therapy signal to autonomic cardiopulmonary fibers surrounding the pulmonary artery. The therapy signal affects heart contractility more than heart rate. Specifically, the application of the therapy signal increases heart contractility and treats the acute heart failure in the patient. The therapy signal can include electrical or chemical modulation.
    Type: Grant
    Filed: November 20, 2013
    Date of Patent: November 1, 2016
    Assignee: The Cleveland Clinic Foundation
    Inventors: Sandra Machado, Marc Penn, Ali R. Rezai
  • Patent number: 8818501
    Abstract: Methods and systems of treating acute heart failure by applying a therapy signal at least one sympathetic cardiopulmonary fiber surrounding the pulmonary trunk that affects heart contractility more than heart rate. Methods and systems also include adjusting the signal to effectuate treatment.
    Type: Grant
    Filed: August 4, 2008
    Date of Patent: August 26, 2014
    Assignee: The Cleveland Clinic Foundation
    Inventors: Sandra Machado, Marc Penn, Ali R. Rezai, Alex Smith
  • Patent number: 8798738
    Abstract: Methods of treating acute heart failure in a patient in need thereof. Methods include inserting a therapy delivery device into a pulmonary artery of the patient and applying a therapy signal to autonomic cardiopulmonary fibers surrounding the pulmonary artery. The therapy signal affects heart contractility more than heart rate. Specifically, the application of the therapy signal increases heart contractility and treats the acute heart failure in the patient. The therapy signal can include electrical or chemical modulation.
    Type: Grant
    Filed: October 18, 2012
    Date of Patent: August 5, 2014
    Assignee: The Cleveland Clinic Foundation
    Inventors: Sandra Machado, Marc Penn, Ali R. Rezai
  • Publication number: 20140074069
    Abstract: Methods of treating acute heart failure in a patient in need thereof. Methods include inserting a therapy delivery device into a pulmonary artery of the patient and applying a therapy signal to autonomic cardiopulmonary fibers surrounding the pulmonary artery. The therapy signal affects heart contractility more than heart rate. Specifically, the application of the therapy signal increases heart contractility and treats the acute heart failure in the patient. The therapy signal can include electrical or chemical modulation.
    Type: Application
    Filed: November 20, 2013
    Publication date: March 13, 2014
    Applicant: Cardionomic
    Inventors: Sandra MACHADO, Marc PENN, Ali R. REZAI
  • Patent number: 7865237
    Abstract: Method of treating hemodynamic derangement and controlling the mobilization of splanchnic circulation. The method comprises applying a therapy signal to a celiac ganglion, a celiac plexus, a splanchnic nerve, or any combination thereof and adjusting the signal to effectuate treatment. The present invention also provides methods of treating hemodynamic derangement and controlling the mobilization of splanchnic circulation by transluminal modulation of the celiac ganglion, the celiac plexus, the splanchnic nerve.
    Type: Grant
    Filed: September 12, 2005
    Date of Patent: January 4, 2011
    Assignee: The Cleveland Clinic Foundation
    Inventors: Sandra Machado, Ali Rezai, Andre Machado
  • Publication number: 20090171411
    Abstract: Methods and systems of treating acute heart failure by applying a therapy signal at least one sympathetic cardiopulmonary fiber surrounding the pulmonary trunk that affects heart contractility more than heart rate. Methods and systems also include adjusting the signal to effectuate treatment.
    Type: Application
    Filed: August 4, 2008
    Publication date: July 2, 2009
    Applicant: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Sandra Machado, Marc Penn, Ali R. Rezai, Alex Smith
  • Patent number: 7532938
    Abstract: A minimally invasive intraluminal electrode assembly that includes a cannulated tube and a plurality of wires disposed within the cannulated tube. Each of the plurality of wires has one of a plurality of electrical contacts on a distal end thereof. The distal portion of the plurality of wires assumes a radially constrained configuration within the cannulated tube in a retracted position and a radially extended position outward of the cannulated tube in a deployed position. The electrode assembly further comprises a spring electrode connecting the plurality of electrical contacts to collectively form a substantially circular configuration in a deployed position.
    Type: Grant
    Filed: September 12, 2005
    Date of Patent: May 12, 2009
    Assignee: The Cleveland Clinic Foundation
    Inventors: Sandra Machado, Andre Machado, Ali Rezai
  • Publication number: 20060100667
    Abstract: Method of treating hemodynamic derangement and controlling the mobilization of splanchnic circulation. The method comprises applying a therapy signal to a celiac ganglion, a celiac plexus, a splanchnic nerve, or any combination thereof and adjusting the signal to effectuate treatment. The present invention also provides methods of treating hemodynamic derangement and controlling the mobilization of splanchnic circulation by transluminal modulation of the celiac ganglion, the celiac plexus, the splanchnic nerve.
    Type: Application
    Filed: September 12, 2005
    Publication date: May 11, 2006
    Inventors: Sandra Machado, Ali Rezai, Andre Machado