Patents by Inventor Sandra Mayrand

Sandra Mayrand has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of site-specific alteration of RNA and production of encoded polypeptides
    Patent number: 5635377
    Abstract: A method of site-directed alteration (removal or removal followed by replacement) of selected nucleotides in an RNA molecule, as well as to mixed phosphate backbone oligonucleotides useful in the method. It further relates to a method of producing polypeptides or proteins encoded by the RNA molecule altered by the present method. Through use of the present method, site-directed cleavage of an RNA molecule is effected, followed by excision of the selected or target segment of the RNA molecule.
    Type: Grant
    Filed: November 18, 1994
    Date of Patent: June 3, 1997
    Assignee: Worcester Foundation for Experimental Biology, Inc.
    Inventors: Thoru Pederson, Sudhir Agrawal, Sandra Mayrand, Paul C. Zamecnik
  • Method of site-specific alteration of RNA and production of encoded polypeptides
    Patent number: 5366878
    Abstract: A method of site-directed alteration (removal or removal followed by replacement) of selected nucleotides in an RNA molecule, as well as to mixed phosphate backbone oligonucleotides useful in the method. It further relates to a method of producing polypeptides or proteins encoded by the RNA molecule altered by the present method. Through use of the present method, site-directed cleavage of an RNA molecule is effected, followed by excision of the selected or target segment of the RNA molecule.
    Type: Grant
    Filed: March 24, 1993
    Date of Patent: November 22, 1994
    Assignee: The Worcester Foundation for Experimental Biology
    Inventors: Thoru Pederson, Sudhir Agrawal, Sandra Mayrand, Paul C. Zamecnik
  • Method of site-specific alteration of RNA and production of encoded polypeptides
    Patent number: 5220007
    Abstract: A method of site-directed alteration (removal or removal followed by replacement) of selected nucleotides in an RNA molecule, as well as to mixed phosphate backbone oligonucleotides useful in the method. It further relates to a method of producing polypeptides or proteins encoded by the RNA molecule altered by the present method. Through use of the present method, site-directed cleavage of an RNA molecule is effected, followed by excision of the selected or target segment of the RNA molecule.
    Type: Grant
    Filed: February 19, 1992
    Date of Patent: June 15, 1993
    Assignee: The Worcester Foundation for Experimental Biology
    Inventors: Thoru Pederson, Sudhir Agrawal, Sandra Mayrand, Paul C. Zamecnik
  • Method of site-specific alteration of RNA and production of encoded polypeptides
    Patent number: 5149797
    Abstract: A method of site-directed alteration (removal or removal followed by replacement) of selected nucleotides in an RNA molecule, as well as to mixed phosphate backbone oligonucleotides useful in the method. It further relates to a method of producing polypeptides or proteins encoded by the RNA molecule altered by the present method. Through use of the present method, site-directed cleavage of an RNA molecule is effected, followed by excision of the selected or target segment of the RNA molecule.
    Type: Grant
    Filed: February 15, 1990
    Date of Patent: September 22, 1992
    Assignee: The Worcester Foundation for Experimental Biology
    Inventors: Thoru Pederson, Sudhir Agrawal, Sandra Mayrand, Paul C. Zamecnik