Patents by Inventor Sandra Nehlsen-Cannarella

Sandra Nehlsen-Cannarella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of detecting colon cancer
    Patent number: 7252955
    Abstract: An immunological assay and kit for colon cancer screening is disclosed. Fecal glycoproteins are extracted from individual samples such that immunogenicity is maintained. The purified fecal glycoproteins are reacted with antibodies to Colon and Ovarian Tumor Antigen (COTA). The mucin antigen COTA is specifically present in colorectal cancer tissue and not in normal colons. The amount of COTA in the fecal sample is determined and used to indicate the presence of colon cancer.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: August 7, 2007
    Assignee: Loma Linda University Adventist Health Sciences Center
    Inventors: Keshab D. Pant, John D. McCracken, Omar Fagoaga, Wayne Kelln, Sandra Nehlsen-Cannarella
  • Method of detecting colon cancer
    Publication number: 20040110234
    Abstract: An immunological assay and kit for colon cancer screening is disclosed. Fecal glycoproteins are extracted from individual samples such that immunogenicity is maintained. The purified fecal glycoproteins are reacted with antibodies to Colon and Ovarian Tumor Antigen (COTA). The mucin antigen COTA is specifically present in colorectal cancer tissue and not in normal colons. The amount of COTA in the fecal sample is determined and used to indicate the presence of colon cancer.
    Type: Application
    Filed: November 25, 2003
    Publication date: June 10, 2004
    Inventors: Keshab D. Pant, John D. McCracken, Omar Fagoaga, Wayne Kelln, Sandra Nehlsen-Cannarella
  • Method of detecting colon cancer
    Patent number: 6703206
    Abstract: An immunological assay and kit for colon cancer screening is disclosed. Fecal glycoproteins are extracted from individual samples such that immunogenicity is maintained. The purified fecal glycoproteins are reacted with antibodies to Colon and Ovarian Tumor Antigen (COTA). The mucin antigen COTA is specifically present in colorectal cancer tissue and not in normal colons. The amount of COTA in the fecal sample is determined and used to indicate the presence of colon cancer.
    Type: Grant
    Filed: July 25, 2001
    Date of Patent: March 9, 2004
    Assignee: Loma Linda University Adventist Health Sciences Center
    Inventors: Keshab D. Pant, John D. McCracken, Omar Fagoaga, Wayne Kelln, Sandra Nehlsen-Cannarella
  • Method of detecting colon cancer
    Patent number: 6531319
    Abstract: An immunological assay and kit for colon cancer screening is disclosed. Fecal glycoproteins are extracted from individual samples such that immunogenicity is maintained. The purified fecal glycoproteins are reacted with antibodies to Colon and Ovarian Tumor Antigen (COTA). The mucin antigen COTA is specifically present in colorectal cancer tissue and not in normal colons. The amount of COTA in the fecal sample is determined and used to indicate the presence of colon cancer.
    Type: Grant
    Filed: May 10, 2000
    Date of Patent: March 11, 2003
    Inventors: Keshab D. Pant, John D. McCracken, Omar Fagoaga, Wayne Kelln, Sandra Nehlsen-Cannarella
  • Method of detecting colon cancer
    Publication number: 20020009760
    Abstract: An immunological assay and kit for colon cancer screening is disclosed. Fecal glycoproteins are extracted from individual samples such that immunogenicity is maintained. The purified fecal glycoproteins are reacted with antibodies to Colon and Ovarian Tumor Antigen (COTA). The mucin antigen COTA is specifically present in colorectal cancer tissue and not in normal colons. The amount of COTA in the fecal sample is determined and used to indicate the presence of colon cancer.
    Type: Application
    Filed: July 25, 2001
    Publication date: January 24, 2002
    Inventors: Keshab D. Pant, John D. McCracken, Omar Fagoaga, Wayne Kelln, Sandra Nehlsen-Cannarella
  • ABO histo-blood group O alleles of the baboon
    Patent number: 6265557
    Abstract: This invention relates to histo-blood group O alleles of baboon. The major O allele retains identifying sequence characteristics of the baboon A allele. Other alleles, including a B-like allele, are also disclosed herein. The O alleles of baboon are closer in sequence similarity to the baboon A and B alleles than are any of the baboon ABO alleles to the human alleles of the ABO locus. This invention also provides materials and methods for identifying O alleles, and carriers of O alleles, as well as methods for producing baboons and baboon cells, tissues, and organs having a group O phenotype. Group O baboons, cells, tissues, and organs of the invention are useful for xenotransplantation.
    Type: Grant
    Filed: May 9, 1997
    Date of Patent: July 24, 2001
    Assignee: Loma Linda University Medical Center
    Inventors: David Diamond, Sandra Nehlsen-Cannarella, Omar R. Fagoaga, Aladar A. Szalay