Patents by Inventor Sandra O. Gollnick

Sandra O. Gollnick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions using peroxiredoxin 1 (PRX1) as an adjuvant
    Patent number: 9050291
    Abstract: Provided are compositions and methods for stimulating immune responses against antigens. The compositions contain an antigen to which a stimulated immune response is desired and an isolated Prx1 protein. The Prx1 protein functions as an adjuvant so that the immune response to the antigen stimulated by the composition comprising the antigen and Prx1 is greater than the immune response stimulated by the antigen alone.
    Type: Grant
    Filed: December 8, 2010
    Date of Patent: June 9, 2015
    Assignee: Health Research Inc.
    Inventors: Sandra O. Gollnick, Jonah Riddell
  • Inhibition of Tumor Angiogenesis by Inhibition of Peroxiredoxin 1 (PRX1)
    Publication number: 20110177091
    Abstract: Provided is a method for inhibiting angiogenesis in a tumor. The method involves administering to an individual who has a tumor a composition that contains an agent capable of inhibiting binding of peroxiredoxin 1 (Prx1) to Toll like receptor 4 (TLR4) such that angiogenesis in the tumor is inhibited subsequent to the administration. The agent that is capable of inhibiting binding of Prx1 to TLR4 can be an antibody to Prx1, a Prx1 binding fragment of the antibody, or a peptide. The peptide can be capable of inhibiting the formation of a Prx1 decamer, or can inhibit binding of Prx1 to TLR4 by steric interference, or by competitions with Prx1 for TLR4 binding. The tumor in which angiognesis is inhibited can be any type of cancer tumor.
    Type: Application
    Filed: December 8, 2010
    Publication date: July 21, 2011
    Inventors: Sandra O. Gollnick, Jonah Riddell
  • Methods and Compositions Using Peroxiredoxin 1 (PRX1) as an Adjuvant
    Publication number: 20110177129
    Abstract: Provided are compositions and methods for stimulating immune responses against antigens. The compositions contain an antigen to which a stimulated immune response is desired and an isolated Prx1 protein. The Prx1 protein functions as an adjuvant so that the immune response to the antigen stimulated by the composition comprising the antigen and Prx1 is greater than the immune response stimulated by the antigen alone.
    Type: Application
    Filed: December 8, 2010
    Publication date: July 21, 2011
    Inventors: Sandra O. Gollnick, Jonah Riddell
  • Core modified porphyrins
    Patent number: 6984656
    Abstract: The present invention is directed to novel photosensitive compounds that can be replicated with great certainty and provide applications for photodynamic therapy.
    Type: Grant
    Filed: July 30, 2002
    Date of Patent: January 10, 2006
    Assignee: The Research Foundation of State University of New York
    Inventors: Michael R. Detty, Sandra O. Gollnick, Sherry Davies, Allan Oseroff, Masako Abe, David Hilmey
  • Core modified porphyrins
    Publication number: 20030069219
    Abstract: The present invention is directed to novel photosensitive compounds that can be replicated with great certainty and provide applications for photodynamic therapy.
    Type: Application
    Filed: July 30, 2002
    Publication date: April 10, 2003
    Inventors: Michael R. Detty, Sandra O. Gollnick, Sherry Davies, Allan Oseroff, Masako Abe, David Hilmey