Patents by Inventor Sandra Orsulic

Sandra Orsulic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Molecular signatures of ovarian cancer
    Patent number: 10253368
    Abstract: Described herein are gene signatures providing prognostic, diagnostic, treatment and molecular subtype classifications of ovarian cancers through generation of ovarian cancer disease signatures (OCDSs) that account for molecular heterogeneity present in gynecological cancers. An ovarian cancer fixed signature (OCFS) is described which relates to the core programming of disease development, in addition to an ovarian cancer stem cell (OCSC) signature. Development various disease signature, suggests personalized treatment strategies focused on molecular subtypes of gynecological cancers, such as triage tests for patients.
    Type: Grant
    Filed: April 17, 2015
    Date of Patent: April 9, 2019
    Assignee: Cedars-Sinai Medical Center
    Inventors: Sandra Orsulic, Beth Y. Karlan, Xiaojiang Cui, Mourad Tighiouart, Dong-Joo Cheon, Zhenqiu Liu
  • OVARIAN CANCER VACCINES AND VACCINATION METHODS
    Publication number: 20150359867
    Abstract: Compositions of multipeptide vaccines including tumor associated antigens, compositions of antigen presenting cell (e.g., dendritic cell) based vaccines presenting epitopes from tumor associated antigens, and methods of making same, are provided herein. Also, disclosed are methods for treating ovarian cancers using such vaccines.
    Type: Application
    Filed: February 14, 2014
    Publication date: December 17, 2015
    Inventors: John S. Yu, Zhenhua Li, Sandra Orsulic, Beth Y. Karlan, James G. Bender
  • MOLECULAR SIGNATURES OF OVARIAN CANCER
    Publication number: 20150322530
    Abstract: Described herein are gene signatures providing prognostic, diagnostic, treatment and molecular subtype classifications of ovarian cancers through generation of ovarian cancer disease signatures (OCDSs) that account for molecular heterogeneity present in gynecological cancers. An ovarian cancer fixed signature (OCFS) is described which relates to the core programming of disease development, in addition to an ovarian cancer stem cell (OCSC) signature. Development various disease signature, suggests personalized treatment strategies focused on molecular subtypes of gynecological cancers, such as triage tests for patients.
    Type: Application
    Filed: April 17, 2015
    Publication date: November 12, 2015
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Sandra Orsulic, Beth Y. Karlan, Xiaojiang Cui, Mourad Tighiouart, Dong-Joo Cheon, Zhenqiu Liu
  • OVARIAN CANCER VACCINES AND VACCINATION METHODS
    Publication number: 20140234350
    Abstract: Compositions of multipeptide vaccines including tumor associated antigens, compositions of antigen presenting cell (e.g., dendritic cell) based vaccines presenting epitopes from tumor associated antigens, and methods of making same, are provided herein. Also, disclosed are methods for treating ovarian cancers using such vaccines.
    Type: Application
    Filed: February 14, 2014
    Publication date: August 21, 2014
    Inventors: John S. Yu, Zhenhua Li, Sandra Orsulic, Beth Y. Karlan, James G. Bender