Patents by Inventor Sandra Uhlenbroich

Sandra Uhlenbroich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS
    Publication number: 20240108738
    Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which bind to natural killer (NK) cells. The invention also includes multimeric binding complexes comprising at least two of said bicyclic peptide ligands. The invention also includes pharmaceutical compositions comprising said peptide ligands or said multimeric binding complexes and the use of said peptide ligands, multimeric binding complexes and pharmaceutical compositions in preventing, suppressing or treating a disease or disorder mediated by natural killer (NK) cells, such as inflammatory disorders, autoimmune disease and cancer.
    Type: Application
    Filed: January 10, 2022
    Publication date: April 4, 2024
    Inventors: Nicholas KEEN, Gemma MUDD, Fay DUFORT, Katie GAYNOR, Liuhong CHEN, Phil BRANDISH, Cris LEITHEISER, Sandra UHLENBROICH, Liz REPASH, Kevin MCDONNELL
  • FC BINDING FRAGMENTS COMPRISING AN OX40 ANTIGEN-BINDING SITE
    Publication number: 20210355228
    Abstract: The application relates to specific binding members that bind OX40. The specific binding members comprise an OX40 antigen-binding site located in a constant domain of the specific binding member and find application in the treatment of cancer and infectious diseases, for example.
    Type: Application
    Filed: July 12, 2019
    Publication date: November 18, 2021
    Applicant: F-star Beta Limited
    Inventors: Mihriban Tuna, Miguel Gaspar, Sandra Uhlenbroich, Katy Everett, Delphine Buffet