Patents by Inventor Sandra W. Ramer
Sandra W. Ramer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250066754Abstract: Disclosed are compositions and methods relating to variant alpha-amylases. The variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing.Type: ApplicationFiled: August 12, 2024Publication date: February 27, 2025Inventors: Jonathan K. Lassila, Sandra W. Ramer
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Publication number: 20250051745Abstract: Disclosed are compositions and methods relating to maltopentaose/maltohexaose-forming ?-amylases. The variant ?-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing.Type: ApplicationFiled: December 16, 2022Publication date: February 13, 2025Inventors: Jonathan LASSILA, Manasi BHATE, Amanda CHAN, Hon Kit CHAN, Chris LEEFLANG, Sandra W. RAMER, Patricia TRAN
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Patent number: 12084694Abstract: Disclosed are compositions and methods relating to variant alpha-amylases. The variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing.Type: GrantFiled: August 26, 2022Date of Patent: September 10, 2024Assignee: DANISCO US INC.Inventors: Jonathan K. Lassila, Sandra W. Ramer
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Publication number: 20230272310Abstract: Home care compositions including a surfactant and an amylase. The amylase includes a recombinant, non-naturally-occurring variant of a parent alpha-amylase, the variant alpha-amylase having at least about 80% identity to SEQ ID NO: 5 and having amino acid substitutions at positions 415 and/or 51 with respect to SEQ ID NO: 5.Type: ApplicationFiled: December 14, 2022Publication date: August 31, 2023Inventors: Katarzyna Dorota BELL-RUSIEWICZ, Michelle JACKSON, Ana L. MORALES GARCIA, Manasi BHATE, Amanda CHAN, Hon Kit CHAN, Jonathan LASSILA, Chris LEEFLANG, Sandra W. RAMER, Patricia TRAN
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Publication number: 20230265358Abstract: Home care compositions including a surfactant and an amylase.Type: ApplicationFiled: December 14, 2022Publication date: August 24, 2023Inventors: Katarzyna Dorota BELL-RUSIEWICZ, Michelle JACKSON, Ana L. MORALES GARCIA, Manasi BHATE, Amanda CHAN, Hon Kit CHAN, Jonathan LASSILA, Chris LEEFLANG, Sandra W. RAMER, Patricia TRAN
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Publication number: 20230227803Abstract: Disclosed are compositions and methods relating to variant alpha-amylases. The variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing.Type: ApplicationFiled: August 26, 2022Publication date: July 20, 2023Inventors: Jonathan K. Lassila, Sandra W. Ramer
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Publication number: 20220403359Abstract: Disclosed are compositions and methods relating to maltopentaose/maltohexaose-forming ?-amylases. The variant ?-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing.Type: ApplicationFiled: October 20, 2020Publication date: December 22, 2022Inventors: MANASI BHATE, HON KIT CHAN, JONATHAN LASSILA, BRIAN JAMES PAUL, SANDRA W. RAMER, PATRICIA TRAN
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Patent number: 11441139Abstract: Disclosed are compositions and methods relating to variant alpha-amylases. The variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing.Type: GrantFiled: August 20, 2018Date of Patent: September 13, 2022Assignee: DANISCO US INC (157111)Inventors: Jonathan K. Lassila, Sandra W. Ramer
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Publication number: 20210189363Abstract: Disclosed are compositions and methods relating to variant alpha-amylases. The variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing.Type: ApplicationFiled: August 20, 2018Publication date: June 24, 2021Inventors: Jonathan K. Lassila, Sandra W. Ramer
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Publication number: 20210122998Abstract: An automatic dishwashing cleaning composition comprising a variant ?-amylase wherein the variant ?-amylase comprises amino acid substitution(s) selected from the group consisting of: i) a mutation at position 91 and one or more mutation(s) at an amino acid residue at the base of the ?-amylase TIM barrel structure, defined as residues 6, 7, 40, 96, 98, 100, 229, 230, 231, 262, 263, 285, 286, 287, 288, 322, 323, 324, 325, 362, 363 and 364; and/or ii) a mutation at position 172 and a mutation in position 288 or 324; and/or iii) Y364L referring to SEQ ID NO: 1 for numbering.Type: ApplicationFiled: October 9, 2020Publication date: April 29, 2021Inventors: Michelle JACKSON, Katarzyna BELL-RUSIEWICZ, Manasi BHATE, Hon Kit CHAN, Jonathan LASSILA, Brian James PAUL, Sandra W. RAMER, Patricia TRAN
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Publication number: 20210095268Abstract: Disclosed are compositions and methods relating to variant alpha-amylases. The variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing.Type: ApplicationFiled: April 2, 2018Publication date: April 1, 2021Inventors: Jonathan Lassila, Sandra W. Ramer
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Patent number: 9282746Abstract: The present invention provides methods and compositions comprising at least one perhydrolase enzyme for cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions for generation of peracids. The present invention finds particular use in applications involving cleaning, bleaching and disinfecting.Type: GrantFiled: May 8, 2014Date of Patent: March 15, 2016Assignee: Danisco US Inc.Inventors: Neelam S. Amin, Matthew G. Boston, Richard R. Bott, Maguerite A. Cervin, Edward M. Concar, Marc E. Gustwiller, Brian E. Jones, Klaus Liebeton, Gregory S. Miracle, Hiroshi Oh, Ayrookaran J. Poulose, Sandra W. Ramer, Jeffrey J. Scheibel, Walter Weyler, Gregory M. Whited
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Publication number: 20160010129Abstract: Alpha-amylases from Bacillus subtilis (AmyE), variants thereof, nucleic acids encoding the same, and host cells comprising the nucleic acids are provided. Methods of using AmyE or variants thereof are disclosed, including liquefaction and/or saccharification of starch. Such methods may yield sugars useful for ethanol production or high fructose corn syrup production. In some cases, the amylases can be used at low pH, in the absence of calcium, and/or in the absence of a glucoamylase.Type: ApplicationFiled: June 17, 2015Publication date: January 14, 2016Inventors: William A. Cuevas, Sang-Kyu Lee, Sandra W. Ramer, Andrew Shaw, Amr R. Toppozada, David A. Estell, Louise Wallace, Regina Chin, Carol A. Requadt, Scott D. Power, Michael J. Pepsin
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Patent number: 9090887Abstract: Alpha-amylases from Bacillus subtilis (AmyE), variants thereof, nucleic acids encoding the same, and host cells comprising the nucleic acids are provided. Methods of using AmyE or variants thereof are disclosed, including liquefaction and/or saccharification of starch. Such methods may yield sugars useful for ethanol production or high fructose corn syrup production. In some cases, the amylases can be used at low pH, in the absence of calcium, and/or in the absence of a glucoamylase.Type: GrantFiled: June 5, 2009Date of Patent: July 28, 2015Assignee: DANISCO US INC.Inventors: William A Cuevas, Sang-Kyu Lee, Sandra W Ramer, Andrew Shaw, Amr R Toppozada, David E Estell, Louise Wallace, Regina Chin, Carol A Requadt, Scott D Power, Michael J Pepsin
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Patent number: 9040278Abstract: An ?-amylase from Bacillus subtilis (AmyE) produces significant amounts of glucose from various carbohydrate substrates, including vegetable starch, maltoheptaose, and maltotriose. Among other things, this advantageous property allows AmyE or variants thereof to be used in a saccharification reaction having a reduced or eliminated requirement for glucoamylase. The reduction or elimination of the glucoamylase requirement significantly improves the efficiency of the production of ethanol or high fructose corn syrup, for example.Type: GrantFiled: June 4, 2009Date of Patent: May 26, 2015Assignee: DANISCO US INC.Inventors: Luis G. Cascao-Pereira, Regina Chin, William A. Cuevas, David A. Estell, Sang-Kyu Lee, Michael J. Pepsin, Scott D. Power, Sandra W. Ramer, Carol A. Requadt, Andrew Shaw, Amr R. Toppozada, Louise Wallace
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Patent number: 8975056Abstract: Alpha-amylases from Bacillus subtilis (AmyE), variants thereof, nucleic acids encoding the same, and host cells comprising the nucleic acids are provided. Methods of using AmyE or variants thereof are disclosed, including liquefaction and/or saccharification of starch. Such methods may yield sugars useful for ethanol production or high fructose corn syrup production. In some cases, the amylases can be used at low pH, in the absence of calcium, and/or in the absence of a glucoamylase.Type: GrantFiled: October 25, 2012Date of Patent: March 10, 2015Assignee: Danisco US Inc.Inventors: Luis G. Cascao-Pereira, William A. Cuevas, David A. Estell, Sang-Kyu Lee, Scott D. Power, Sandra W. Ramer, Amr Toppozada, Louise Wallace
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Publication number: 20140302003Abstract: The present invention provides methods and compositions comprising at least one perhydrolase enzyme for cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions for generation of peracids. The present invention finds particular use in applications involving cleaning, bleaching and disinfecting.Type: ApplicationFiled: May 8, 2014Publication date: October 9, 2014Applicant: DANISCO US INC.Inventors: Neelam S. Amin, Matthew G. Boston, Richard R. Bott, Maguerite A. Cervin, Edward M. Concar, Marc E. Gustwiller, Brian E. Jones, Klaus Liebeton, Gregory S. Miracle, Hiroshi Oh, Ayrookaran J. Poulose, Sandra W. Ramer, Jeffrey J. Scheibel, Walter Weyler, Gregory M. Whited
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Patent number: 8772007Abstract: The present invention provides methods and compositions comprising at least one perhydrolase enzyme for cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions for generation of peracids. The present invention finds particular use in applications involving cleaning, bleaching and disinfecting.Type: GrantFiled: December 3, 2004Date of Patent: July 8, 2014Assignee: Danisco US Inc.Inventors: Neelam S. Amin, Matthew G. Boston, Richard R. Bott, Marguerite A. Cervin, Edward M. Concar, Marc E. Gustwiller, Brian E. Jones, Klaus Liebeton, Gregory S. Miracle, Hiroshi Oh, Ayrookaran J. Poulose, Sandra W. Ramer, Jeffrey J. Scheibel, Walter Weyler, Gregory M. Whited
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Patent number: 8722381Abstract: Described are variants of alpha (?)-amylases having altered starch hydrolysis profiles. The variants have improved thermostability and increased specific activity, resulting in reduced peak viscosity and altered final viscosity during starch liquefaction. The amylase variants are useful, e.g., in liquefaction and other starch degradation processes.Type: GrantFiled: February 4, 2009Date of Patent: May 13, 2014Assignee: Danisco US Inc.Inventors: Sandra W. Ramer, Michael J. Pepsin, Andrew Shaw
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Publication number: 20130011882Abstract: Disclosed are compositions comprising variants of alpha-amylase that have alpha-amylase activity and which exhibit altered properties relative to a parent AmyS-like alpha-amylase from which they are derived. The compositions comprise an additional enzyme such as a phytase. Also disclosed are methods of using the compositions, and kits related thereto.Type: ApplicationFiled: May 15, 2012Publication date: January 10, 2013Applicant: DANISCO US INC.Inventors: LUIS G. CASCĂO-PEREIRA, JAMES T. KELLIS, JR., BRADLEY A. PAULSON, SCOTT D. POWER, SANDRA W. RAMER, VIVEK SHARMA, ANDREW SHAW, JAYARAMA K. SHETTY, DONALD E. WARD