Patents by Inventor Sandra Welz

Sandra Welz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pseudo proline dipeptides
    Patent number: 7612209
    Abstract: Disclosed is a process for the manufacture of pseudo proline dipeptides of the formula wherein R1 is a side chain of an alpha amino acid, R2 is an amino protecting group and R3 and R4 are independently either hydrogen or C1-4-alkyl, and R5 is hydrogen or methyl starting from an amino acid derivative of the formula wherein R1 and R2 are as defined above. Pseudo proline dipeptides can be used as reversible protecting groups for Ser, Thr and Cys and thus are versatile tools in peptide chemistry.
    Type: Grant
    Filed: June 14, 2007
    Date of Patent: November 3, 2009
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Thomas Ammann, Stephan Goetzoe, Bernd Thern, Sandra Welz, Klaus-Juergen Wolter
  • Pseudo proline dipeptides
    Publication number: 20080004451
    Abstract: Disclosed is a process for the manufacture of pseudo proline dipeptides of the formula wherein R1 is a side chain of an alpha amino acid, R2 is an amino protecting group and R3 and R4 are independently either hydrogen or C1-4-alkyl, and R5 is hydrogen or methyl starting from an amino acid derivative of the formula wherein R1 and R2 are as defined above. Pseudo proline dipeptides can be used as reversible protecting groups for Ser, Thr and Cys and thus are versatile tools in peptide chemistry.
    Type: Application
    Filed: June 14, 2007
    Publication date: January 3, 2008
    Inventors: Thomas Ammann, Stephan Goetzoe, Bernd Thern, Sandra Welz, Klaus-Juergen Wolter