Patents by Inventor Sandrine Busseret
Sandrine Busseret has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210405034Abstract: A bi-epitope compound of formula (I): in which (i) E1 and E2, which may be identical or different, each independently represent a peptide sequence comprising at least one epitope of an analyte, (ii) X and Y, which may be identical or different, each independently represent a linker arm, (iii) the carrier molecule is soluble, and (iv) Z represents an amino acid derivative that had a thiol function before the bonding thereof with the carrier molecule.Type: ApplicationFiled: September 16, 2021Publication date: December 30, 2021Applicant: BIOMERIEUXInventors: Florence BETTSWORTH, Sandrine BUSSERET, Catherine POTHION
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Patent number: 11193929Abstract: A bi-epitope compound of formula I: in which: E1 and E2, identical or different, each separately represents a peptide sequence including at least one epitope of an analyte; X and Y, identical or different, each separately represents a linking arm, the carrier molecule is soluble and Z represents an amino acid derivative bearing a thiol function prior to the bonding of same with the carrier molecule. The compound may be contained in a composition, used as a control or standard in an immunoassay and associated method, and/or provided in a kit for implementing an immunoassay.Type: GrantFiled: December 17, 2015Date of Patent: December 7, 2021Assignee: BIOMERIEUXInventors: Florence Bettsworth, Sandrine Busseret, Catherine Pothion
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Patent number: 11009505Abstract: An immunoassay composition includes at least (i) an amphipol and (ii) a (meth)acrylate monomer-based amphoteric copolymer, some of said monomers including a phosphorylcholine group. The composition is useful in particular as a stabilizer and/or blocking agent.Type: GrantFiled: December 20, 2016Date of Patent: May 18, 2021Assignee: BIOMERIEUXInventors: Sandrine Busseret, Florence Bettsworth, Jérôme Martinez
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Publication number: 20190204308Abstract: An immunoassay composition includes at least (i) an amphipol and (ii) a (meth)acrylate monomer-based amphoteric copolymer, some of said monomers including a phosphorylcholine group. The composition is useful in particular as a stabilizer and/or blocking agent.Type: ApplicationFiled: December 20, 2016Publication date: July 4, 2019Applicant: BIOMERIEUXInventors: Sandrine BUSSERET, Florence BETTSWORTH, Jérôme MARTINEZ
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Patent number: 9890196Abstract: A method for the in vitro diagnosis of colorectal cancer by determining the presence of the Ezrin tumor marker in a biological sample taken from a patient suspected of having colorectal cancer using at least one anti-Ezrin monoclonal antibody directed against an Ezrin epitope chosen from the epitopes of sequence SEQ ID No.1, SEQ ID No.2, SEQ ID No.3, SEQ ID No.4+SEQ ID No.5, SEQ ID No.6+SEQ ID No.7 and SEQ ID No.8. Said method can be used for early diagnosis, screening, therapeutic follow-up and prognosis, and also for relapse diagnosis in relation to colorectal cancer.Type: GrantFiled: December 12, 2012Date of Patent: February 13, 2018Assignees: BIOMERIEUX, CENTRE NATIONALE DE RECHERCHE SCIENTIFIQUE, INSTITUT CURIEInventors: Yasemin Ataman-Onal, Sandrine Busseret, Jean-Philippe Charrier, Genevieve Choquet-Kastylevsky
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Patent number: 9778260Abstract: Disclosed is a process for in vitro detection of an infection by a dengue virus in an individual, including the following steps: contacting a blood sample from the individual with a ligand specific to the NS1 protein of said dengue virus, to capture NS1 protein if it is present in the blood sample, said ligand being immobilized on a solid support; detecting the presence of NS1 protein via a mass spectrometry reading; and if NS1 protein is detected, concluding that the individual has been infected by dengue virus.Type: GrantFiled: April 26, 2012Date of Patent: October 3, 2017Assignee: BIOMERIEUXInventors: Frederic Bedin, Sandrine Busseret, Marine Steidel
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Publication number: 20170269070Abstract: A bi-epitope compound of formula I: in which: E1 and E2, identical or different, each separately represents a peptide sequence including at least one epitope of an analyte; X and Y, identical or different, each separately represents a linking arm, the carrier molecule is soluble and Z represents an amino acid derivative bearing a thiol function prior to the bonding of same with the carrier molecule. The compound may be contained in a composition, used as a control or standard in an immunoassay and associated method, and/or provided in a kit for implementing an immunoassay.Type: ApplicationFiled: December 17, 2015Publication date: September 21, 2017Applicant: BIOMERIEUXInventors: Florence BETTSWORTH, Sandrine BUSSERET, Catherine POTHION
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Patent number: 9388404Abstract: A method for the in vitro diagnosis of colorectal cancer that comprises determining the presence of the protein disulfide isomerase tumor marker in a biological sample taken from a patient suspected of having colorectal cancer using at least one anti-PDI monoclonal antibody directed against a PDI epitope chosen from the epitopes of sequence SEQ ID No.1, SEQ ID No.2, with an aromatic amino acid which is close in the three-dimensional structure of PDI and SEQ ID No.3.Type: GrantFiled: January 2, 2013Date of Patent: July 12, 2016Assignee: BIOMERIEUXInventors: Yasemin Ataman-Onal, Sandrine Busseret, Jean-Philippe Charrier, Genevieve Choquet-Kastylevsky
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Patent number: 9377474Abstract: The present invention relates to a method for the in vitro diagnosis of colorectal cancer by determining the presence of the Prodefensin-A6 tumor marker in a biological sample taken from a patient suspected of having colorectal cancer, it being possible for said method to be used both in early diagnosis, screening, therapeutic follow-up and prognosis, and in relapse diagnosis in relation to colorectal cancer.Type: GrantFiled: May 22, 2015Date of Patent: June 28, 2016Assignee: BIOMERIEUXInventors: Yasemin Ataman-Önal, Corinne Beaulieu, Sandrine Busseret, Jean-Philippe Charrier, Geneviève Choquet-Kastylevsky, Dominique Rolland
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Publication number: 20150253342Abstract: The present invention relates to a method for the in vitro diagnosis of colorectal cancer by determining the presence of the Prodefensin-A6 tumour marker in a biological sample taken from a patient suspected of having colorectal cancer, it being possible for said method to be used both in early diagnosis, screening, therapeutic follow-up and prognosis, and in relapse diagnosis in relation to colorectal cancer.Type: ApplicationFiled: May 22, 2015Publication date: September 10, 2015Inventors: Yasemin ATAMAN-ÖNAL, Corinne BEAULIEU, Sandrine BUSSERET, Jean-Philippe CHARRIER, Geneviève CHOQUET-KASTYLEVSKY, Dominique ROLLAND
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Publication number: 20150233933Abstract: A method for the in vitro diagnosis of colorectal cancer by determining the presence of the Ezrin tumor marker in a biological sample taken from a patient suspected of having colorectal cancer using at least one anti-Ezrin monoclonal antibody directed against an Ezrin epitope chosen from the epitopes of sequence SEQ ID No.1, SEQ ID No.2, SEQ ID No.3, SEQ ID No.4+SEQ ID No.5, SEQ ID No.6+SEQ ID No.7 and SEQ ID No.8. Said method can be used for early diagnosis, screening, therapeutic follow-up and prognosis, and also for relapse diagnosis in relation to colorectal cancer.Type: ApplicationFiled: April 30, 2015Publication date: August 20, 2015Applicants: BIOMERIEUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT CURIEInventors: Yasemin ATAMAN-ONAL, Sandrine BUSSERET, Jean-Philippe CHARRIER, Genevieve CHOQUET-KASTYLEVSKY
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Patent number: 9062099Abstract: The present invention relates to a method for the in vitro diagnosis of colorectal cancer by determining the presence of the Prodefensin-A6 tumour marker in a biological sample taken from a patient suspected of having colorectal cancer, it being possible for said method to be used both in early diagnosis, screening, therapeutic follow-up and prognosis, and in relapse diagnosis in relation to colorectal cancer.Type: GrantFiled: April 1, 2010Date of Patent: June 23, 2015Assignee: BIOMERIEUXInventors: Yasemin Ataman-Önal, Corinne Beaulieu, Sandrine Busseret, Jean-Philippe Charrier, Geneviève Choquet-Kastylevsky, Dominique Rolland
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Publication number: 20140051067Abstract: Disclosed is a process for in vitro detection of an infection by a dengue virus in an individual, including the following steps: contacting a blood sample from the individual with a ligand specific to the NS1 protein of said dengue virus, to capture NS1 protein if it is present in the blood sample, said ligand being immobilized on a solid support; detecting the presence of NS1 protein via a mass spectrometry reading; and if NS1 protein is detected, concluding that the individual has been infected by dengue virus.Type: ApplicationFiled: April 26, 2012Publication date: February 20, 2014Applicant: BIOMERIEUXInventors: Frederic Bedin, Sandrine Busseret, Marine Steidel
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Publication number: 20140039154Abstract: A method for the in vitro diagnosis of colorectal cancer that comprises determining the presence of the protein disulfide isomerase tumor marker in a biological sample taken from a patient suspected of having colorectal cancer using at least one anti-PDI monoclonal antibody directed against a PDI epitope chosen from the epitopes of sequence SEQ ID No.1, SEQ ID No.2, with an aromatic amino acid which is close in the three-dimensional structure of PDI and SEQ ID No.3.Type: ApplicationFiled: January 2, 2013Publication date: February 6, 2014Applicant: BIOMERIEUXInventors: Yasemin ATAMAN-ONAL, Sandrine BUSSERET, Jean-Philippe CHARRIER, Genevieve CHOQUET-KASTYLEVSKY
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Publication number: 20140017710Abstract: The object of the present invention is a process for in vitro diagnosis of a prostate cancer, according to which a urine sample to be analysed is contacted with two antibodies, a capture antibody and a detection antibody, one of the two antibodies being directed against the first repeat domain of native human Annexin A3 identified as SEQ ID NO: 1, and the other of the two antibodies being directed against the fourth repeat domain of native human Annexin A3, identified as SEQ ID NO: 2, as well as a kit for implementing the process.Type: ApplicationFiled: December 7, 2011Publication date: January 16, 2014Applicant: BIOMERIEUXInventors: Yasemin Ataman-Onal, Sandrine Busseret, Genevieve Choquet-Kastylevsky, Emanuelle Gallet-Gorius, Gaspard Gervasi, Michele Guillotte, Celine Hamelin
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Patent number: 8367806Abstract: A method for the in vitro diagnosis of colorectal cancer by determining the presence of the protein disulfide isomerase tumor marker in a biological sample taken from a patient suspected of having colorectal cancer using at least one anti-PDI monoclonal antibody directed against a PDI epitope chosen from the epitopes of sequence SEQ ID NO: 1, SEQ ID NO: 2 with an aromatic amino acid having a three-dimensional structure similar to that of PDI, and SEQ ID NO: 3.Type: GrantFiled: July 9, 2009Date of Patent: February 5, 2013Assignee: BiomerieuxInventors: Yasemin Ataman-Onal, Corinne Beaulieu, Sandrine Busseret, Jean-Philippe Charrier, Genevieve Choquet-Kastylevsky, Dominique Rolland
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Patent number: 8361731Abstract: A method for the in vitro diagnosis of colorectal cancer by determining the presence of the Ezrin tumor marker in a biological sample taken from a patient suspected of having colorectal cancer using at least one anti-Ezrin monoclonal antibody directed against an Ezrin epitope chosen from the epitopes of sequence SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3, SEQ ID No. 4+SEQ ID No. 5, SEQ ID No. 6+SEQ ID No. 7 and SEQ ID No. 8. Said method can be used for early diagnosis, screening, therapeutic follow-up and prognosis, and also for relapse diagnosis in relation to colorectal cancer.Type: GrantFiled: July 10, 2008Date of Patent: January 29, 2013Assignees: Biomerieux, Centre National de la Recherche Scientifique, Institut CurieInventors: Monique Arpin, Yasmin Ataman-Onal, Corinne Beaulieu, Sandrine Busseret, Jean-Philippe Charrier, Genevieve Choquet-Kastylevsky, Dominique Rolland
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Publication number: 20120129200Abstract: The present invention relates to a method for the in vitro diagnosis of colorectal cancer by determining the presence of the Prodefensin-A6 tumour marker in a biological sample taken from a patient suspected of having colorectal cancer, it being possible for said method to be used both in early diagnosis, screening, therapeutic follow-up and prognosis, and in relapse diagnosis in relation to colorectal cancer.Type: ApplicationFiled: April 1, 2010Publication date: May 24, 2012Applicant: BIOMERIEUXInventors: Yasemin Ataman-Önal, Corinne Beaulieu, Sandrine Busseret, Jean-Philippe Charrier, Geneviève Choquet-Kastylevsky, Dominique Rolland
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Publication number: 20110104701Abstract: A method for the in vitro diagnosis of colorectal cancer by determining the presence of the protein disulfide isomerase tumor marker in a biological sample taken from a patient suspected of having colorectal cancer using at least one anti-PDI monoclonal antibody directed against a PDI epitope chosen from the epitopes of sequence SEQ ID NO: 1, SEQ ID NO: 2 with an aromatic amino acid having a three-dimensional structure similar to that of PDI, and SEQ ID NO: 3.Type: ApplicationFiled: July 9, 2009Publication date: May 5, 2011Applicant: BIOMERIEUXInventors: Yasemin Ataman-Onal, Corinne Beaulieu, Sandrine Busseret, Jean-Philippe Charrier, Genevieve Choquet-Kastylevsky, Dominique Rolland
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Publication number: 20100136539Abstract: A method for the in vitro diagnosis of colorectal cancer by determining the presence of the Ezrin tumor marker in a biological sample taken from a patient suspected of having colorectal cancer using at least one anti-Ezrin monoclonal antibody directed against an Ezrin epitope chosen from the epitopes of sequence SEQ ID No.1, SEQ ID No.2, SEQ ID No.3, SEQ ID No.4+SEQ ID No.5, SEQ ID No.6+SEQ ID No.7 and SEQ ID No.8. Said method can be used for early diagnosis, screening, therapeutic follow-up and prognosis, and also for relapse diagnosis in relation to colorectal cancer.Type: ApplicationFiled: July 10, 2008Publication date: June 3, 2010Inventors: Monique Arpin, Yasmin Ataman-Onal, Corinne Beaulieu, Sandrine Busseret, Jean-Philippe Charrier, Genevieve Choquet-Kastylevsky, Dominique Rolland