Patents by Inventor Sandrine Cigarini

Sandrine Cigarini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilizing Formulations for Recombinant Viruses
    Publication number: 20150265688
    Abstract: This invention relates to preparations of viruses, e.g. for vaccine or other pharmaceutical or research use, to their stabilization, and to processes of producing such preparations, as well as to their use, e.g. as vaccines or as virus vectors. The formulations comprise a sugar, a preservative, a dispersing agent, a thermal stability agent, a buffer, and up to three distinct types of amino acids without impacting the structural appearance of the lyophilized product.
    Type: Application
    Filed: June 2, 2015
    Publication date: September 24, 2015
    Inventor: Sandrine Cigarini
  • Stabilizing excipient for inactivated whole virus vaccine
    Patent number: 9028839
    Abstract: The invention relates to a vaccine composition comprising: a) inactivated whole virus, and b) a stabilizing excipient which comprises: i. a buffer solution, ii. a mixture of essential and nonessential amino acids, iii. a disaccharide, iv. a polyol, v. a chelating agent, vi. urea or a urea derivative, and vii. a nonionic surfactant.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: May 12, 2015
    Assignee: Sanofi Pasteur S.A.
    Inventors: Alain Francon, Michel Chevalier, Nadege Moreno, Eric Calvosa, Sandrine Cigarini, Virginie Fabre
  • Antigen-adjuvant compositions and methods
    Patent number: 8790658
    Abstract: Vitreous compositions of an antigen and adjuvant, and methods for making the compositions are disclosed. Also disclosed are pharmaceutically acceptable formulations of the vitreous compositions, reconstituted liquid formulations of the vitreous compositions, vaccine compositions, and kits containing the vitreous compositions. Also disclosed are devices for administering the vitreous compositions to mammals and methods for eliciting an immune response in mammals by administering the compositions.
    Type: Grant
    Filed: July 25, 2008
    Date of Patent: July 29, 2014
    Assignee: Sanofi Pasteur Limited
    Inventors: Sandrine Cigarini, Kevin Harper, Manvi Hasija
  • STABILIZING EXCIPIENT FOR INACTIVATED WHOLE VIRUS VACCINE
    Publication number: 20140037684
    Abstract: The invention relates to a vaccine composition comprising: a) inactivated whole virus, and b) a stabilizing excipient which comprises: i. a buffer solution, ii. a mixture of essential and nonessential amino acids, iii. a disaccharide, iv. a polyol, v. a chelating agent, vi. urea or a urea derivative, and vii. a nonionic surfactant.
    Type: Application
    Filed: October 8, 2013
    Publication date: February 6, 2014
    Applicant: Sanofi Pasteur
    Inventors: Alain Francon, Michel Chevalier, Nadege Moreno, Eric Calvosa, Sandrine Cigarini, Virginie Fabre
  • Stabilizing excipient for inactivated whole virus vaccine
    Patent number: 8557253
    Abstract: The invention relates to a vaccine composition comprising: a) inactivated whole virus, and b) a stabilizing excipient which comprises: i. a buffer solution, ii. a mixture of essential and nonessential amino acids, iii. a disaccharide, iv. a polyol, v. a chelating agent, vi. urea or a urea derivative, and vii. a nonionic surfactant.
    Type: Grant
    Filed: October 6, 2010
    Date of Patent: October 15, 2013
    Assignee: Sanofi Pasteur SA
    Inventors: Alain Francon, Michel Chevalier, Nadege Moreno, Eric Calvosa, Sandrine Cigarini, Virginie Fabre
  • Stabilizing Excipient for Inactivated Whole Virus Vaccine
    Publication number: 20110081380
    Abstract: The invention relates to a vaccine composition comprising: a) inactivated whole virus, and b) a stabilizing excipient which comprises: i. a buffer solution, ii. a mixture of essential and nonessential amino acids, iii. a disaccharide, iv. a polyol, v. a chelating agent, vi. urea or a urea derivative, and vii. a nonionic surfactant.
    Type: Application
    Filed: October 6, 2010
    Publication date: April 7, 2011
    Applicant: SANOFI PASTEUR
    Inventors: Alain Françon, Michel Chevalier, Nadège Moreno, Eric Calvosa, Sandrine Cigarini, Virginie Fabre
  • Antigen-Adjuvant Compositions and Methods
    Publication number: 20090110699
    Abstract: Vitreous compositions of an antigen and adjuvant, and methods for making the compositions are disclosed. Also disclosed are pharmaceutically acceptable formulations of the vitreous compositions, reconstituted liquid formulations of the vitreous compositions, vaccine compositions, and kits containing the vitreous compositions. Also disclosed are devices for administering the vitreous compositions to mammals and methods for eliciting an immune response in mammals by administering the compositions.
    Type: Application
    Filed: July 25, 2008
    Publication date: April 30, 2009
    Inventors: Sandrine Cigarini, Kevin Harper, Manvi Hasija