Patents by Inventor Sandrine Mailler

Sandrine Mailler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for inactivation and extraction of acid-fast bacteria for characterization and/or identification using mass spectrometry
    Patent number: 8735091
    Abstract: The present invention is directed to a method for inactivation and/or extraction of acid-fast bacteria (e.g., mycobacteria or nocardia), the method comprising the following sequential steps: (a) acquiring a test sample known to contain or that may contain acid-fast bacteria and suspending the test sample in a container containing ethanol and beads; (b) bead beating and/or vortexing the container to break up clumps and/or disrupt acid-fast bacteria cells in the container; and (c) subsequently incubating the suspension for at least about 3 minutes at room temperature to inactivate any acid-fast bacteria contained in the test sample. In accordance with the present invention, the test sample can subsequently be pelleted by centrifugation, resuspended with formic acid, acetonitrile added, and subjected to mass spectrometry for characterization and/or identification of the acid-fast bacteria.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: May 27, 2014
    Assignee: BioMerieux, Inc.
    Inventors: Jones M. Hyman, Parampal Deol, Elizabeth Miller, Victoria Girard, Amber Gates, Sandrine Mailler, Maud Arsac, John Walsh
  • Methods for Inactiviation And Extraction of Acid-Fast Bacteria for Characterization And/Or Identification Using Mass Spectrometry
    Publication number: 20130309714
    Abstract: The present invention is directed to a method for inactivation and/or extraction of acid-fast bacteria (e.g., mycobacteria or nocardia), the method comprising the following sequential steps: (a) acquiring a test sample known to contain or that may contain acid-fast bacteria and suspending the test sample in a container containing ethanol and beads; (b) bead beating and/or vortexing the container to break up clumps and/or disrupt acid-fast bacteria cells in the container; and (c) subsequently incubating the suspension for at least about 3 minutes at room temperature to inactivate any acid-fast bacteria contained in the test sample. In accordance with the present invention, the test sample can subsequently be pelleted by centrifugation, resuspended with formic acid, acetonitrile added, and subjected to mass spectrometry for characterization and/or identification of the acid-fast bacteria.
    Type: Application
    Filed: March 14, 2013
    Publication date: November 21, 2013
    Applicant: bioMerieux, Inc.
    Inventors: Jones Hyman, Parampal Deol, Elizabeth Miller, Victoria Girard, Amber Gates, Sandrine Mailler, Maud Arsac, John Walsh