Patents by Inventor Sandy Fabre

Sandy Fabre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3beta-(4-methoxybenzyloxy)pregn-5-en-20-one for use in the treatment of Cannabinoids-Related Disorders
    Publication number: 20230226076
    Abstract: The present invention generally relates to a specific pregnenolone derivative for its use for the treatment of a Cannabinoids-Related Disorder. More particularly, the invention relates to a compound of Formula (I) for its use in the treatment of a Cannabinoids-Related Disorder. Indeed, the compound of the invention is in vivo very potent in inhibiting the effects of THC, and is able to inhibit both unconditioned and conditioned effects of THC including THC self-administration and reinstatement in THC seeking in non-human primates.
    Type: Application
    Filed: September 15, 2022
    Publication date: July 20, 2023
    Inventors: Pier Vincenzo PIAZZA, Sandy FABRE, Mathilde METNA, Stéphanie MONLEZUN, Arnau BUSQUET-GARCIA, Daniela COTA, Giovanni MARSICANO, Jean-Michel REVEST, Monique VALLEE
  • 3?-(4-methoxybenzyloxy)pregn-5-en-20-one for use in the treatment of cannabinoids-related disorders
    Patent number: 11484537
    Abstract: The present invention generally relates to a specific pregnenolone derivative for its use for the treatment of a Cannabinoids-Related Disorder. More particularly, the invention relates to a compound of Formula (I) for its use in the treatment of a Cannabinoids-Related Disorder. Indeed, the compound of the invention is in vivo very potent in inhibiting the effects of THC, and is able to inhibit both unconditioned and conditioned effects of THC including THC self-administration and reinstatement in THC seeking in non-human primates.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: November 1, 2022
    Assignees: AELIS FARMA, INSERM (Institut National de la Santé et de la Recherche Médicale), UNIVERSITE DE BORDEAUX
    Inventors: Pier Vincenzo Piazza, Sandy Fabre, Mathilde Metna, Stéphanie Monlezun, Arnau Busquet-Garcia, Daniela Cota, Giovanni Marsicano, Jean-Michel Revest, Monique Vallée
  • 3beta-(benzyloxy)-17alpha-methyl-pregn-5-en-20-one for use in the treatment of cognitive disorders
    Publication number: 20220017562
    Abstract: The present invention generally relates to a specific pregnenolone derivative for its use for the treatment of a cognitive disorders. More particularly, the invention relates to a compound of Formula (I) for its use in the treatment of cognitive disorders. Indeed, the compound of the invention is in vivo very potent in correcting the cognitive impairments observed in cognitive disorders.
    Type: Application
    Filed: December 18, 2019
    Publication date: January 20, 2022
    Inventors: Pier Vincenzo PIAZZA, Sandy FABRE, Stéphanie MONLEZUN, Mathilde METNA, Monique VALLEE, Jean-Michel REVEST, Daniela COTA, Giovanni MARSICANO, Aline MARIGHETTO, Andrés OZAITA, Rafael MALDONADO
  • 3-(4'-SUBSTITUTED)-BENZYL-ETHER DERIVATIVES OF PREGNENOLONE
    Publication number: 20210230211
    Abstract: The invention relates to a compound of Formula (I), or a pharmaceutically acceptable salt thereof: wherein R1 is C1-8 alkyl, C1-8 alkoxy, CN, NO2, amino, COOH, COOCH3, OH, N3, or halogen and R2 is H, OH, C1-8 alkyl, C1-8 alkoxy, C2-C6 alkenyl, halogen, Bn-O—, Bn- optionally substituted, or Ph- optionally substituted.
    Type: Application
    Filed: December 1, 2020
    Publication date: July 29, 2021
    Inventors: Pier Vincenzo PIAZZA, Monique VALLEE, Francois-Xavier FELPIN, Jean-Michel REVEST, Sandy FABRE
  • 3beta-(4-methoxybenzyloxy)pregn-5-en-20-one for use in the treatment of Cannabinoids-Related Disorders
    Publication number: 20210030768
    Abstract: The present invention generally relates to a specific pregnenolone derivative for its use for the treatment of a Cannabinoids-Related Disorder. More particularly, the invention relates to a compound of Formula (I) for its use in the treatment of a Cannabinoids-Related Disorder. Indeed, the compound of the invention is in vivo very potent in inhibiting the effects of THC, and is able to inhibit both unconditioned and conditioned effects of THC including THC self-administration and reinstatement in THC seeking in non-human primates.
    Type: Application
    Filed: February 20, 2019
    Publication date: February 4, 2021
    Inventors: Pier Vincenzo PIAZZA, Sandy FABRE, Mathilde METNA, Stephanie MONLEZUN, Arnau BUSQUET-GARCIA, Daniela COTA, Giovanni MARSICANO, Jean-Michel REVEST, Monique VALLEE
  • 3-(4'-SUBSTITUTED)-BENZYL-ETHER DERIVATIVES OF PREGNENOLONE
    Publication number: 20190202857
    Abstract: The invention relates to a compound of Formula (I), or a pharmaceutically acceptable salt thereof: wherein R1 is C1-8 alkyl, C1-8 alkoxy, CN, NO2, amino, COOH, COOCH3, OH, N3, or halogen and R2 is H, OH, C1-8 alkyl, C1-8 alkoxy, C2-C6 alkenyl, halogen, Bn-O—, Bn- optionally substituted, or Ph- optionally substituted.
    Type: Application
    Filed: March 11, 2019
    Publication date: July 4, 2019
    Inventors: Pier Vincenzo Piazza, Monique Vallee, Francois-Xavier Felpin, Jean-Michel Revest, Sandy Fabre
  • 3-(4?-substituted)-benzyl-ether derivatives of pregnenolone
    Patent number: 10259839
    Abstract: The invention relates to a compound of Formula (I), or a pharmaceutically acceptable salt thereof: wherein R1 is C1-8 alkyl, C1-8 alkoxy, CN, NO2, amino, COOH, COOCH3, OH, N3, or halogen and R2 is H, OH, C1-8 alkyl, C1-8 alkoxy, C2-C6 alkenyl, halogen, Bn-O—, Bn- optionally substituted, or Ph- optionally substituted.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: April 16, 2019
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), SC BELENOS, UNIVERSITE DE BORDEAUX
    Inventors: Pier Vincenzo Piazza, Monique Vallee, Francois-Xavier Felpin, Jean-Michel Revest, Sandy Fabre
  • 3-(4?-substituted)-benzyl-ether derivatives of pregnenolone
    Patent number: 9732115
    Abstract: The invention relates to a compound of Formula (I), or a pharmaceutically acceptable salt thereof: wherein R1 is C1-8 alkyl, C1-8 alkoxy, CN, NO2, amino, COOH, COOCH3, OH, N3, or halogen and R2 is H, OH, C1-8 alkyl, C1-8 alkoxy, C2-C6 alkenyl, halogen, Bn-O—, Bn- optionally substituted, or Ph- optionally substituted.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: August 15, 2017
    Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), SC BELENOS, Universite de Bordeaux
    Inventors: Pier Vincenzo Piazza, Monique Vallee, Francois-Xavier Felpin, Jean-Michel Revest, Sandy Fabre
  • 3-(4'-SUBSTITUTED)-BENZYL-ETHER DERIVATIVES OF PREGNENOLONE
    Publication number: 20170226148
    Abstract: The invention relates to a compound of Formula (I), or a pharmaceutically acceptable salt thereof: wherein R1 is C1-8 alkyl, C1-8 alkoxy, CN, NO2, amino, COOH, COOCH3, OH, N3, or halogen and R2 is H, OH, C1-8 alkyl, C1-8 alkoxy, C2-C6 alkenyl, halogen, Bn-O—, Bn- optionally substituted, or Ph- optionally substituted.
    Type: Application
    Filed: April 25, 2017
    Publication date: August 10, 2017
    Inventors: Pier Vincenzo Piazza, Monique Vallee, Francois-Xavier Felpin, Jean-Michel Revest, Sandy Fabre
  • 3-(4?-substituted)-benzyl-ether derivatives of pregnenolone
    Patent number: 9657051
    Abstract: The invention relates to a compound of Formula (I), or a pharmaceutically acceptable salt thereof: wherein R1 is C1-8 alkyl, C1-8 alkoxy, CN, NO2, amino, COOH, COOCH3, OH, N3, or halogen and R2 is H, OH, C1-8 alkyl, C1-8 alkoxy, C2-C6 alkenyl, halogen, Bn-O—, Bn- optionally substituted, or Ph- optionally substituted.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: May 23, 2017
    Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), SC BELENOS, Universite de Bordeaux
    Inventors: Pier Vincenzo Piazza, Monique Vallee, Francois-Xavier Felpin, Jean-Michel Revest, Sandy Fabre
  • 3-(4'-SUBSTITUTED)-BENZYL-ETHER DERIVATIVES OF PREGNENOLONE
    Publication number: 20150284423
    Abstract: The invention relates to a compound of Formula (I), or a pharmaceutically acceptable salt thereof: wherein R1 is C1-8 alkyl, C1-8 alkoxy, CN, NO2, amino, COOH, COOCH3, OH, N3, or halogen and R2 is H, OH, C1-8 alkyl, C1-8 alkoxy, C2-C6 alkenyl, halogen, Bn-O—, Bn- optionally substituted, or Ph- optionally substituted.
    Type: Application
    Filed: November 27, 2013
    Publication date: October 8, 2015
    Inventors: Pier Vincenzo Piazza, Monique Vallee, Francois-Xavier Felpin, Jean-Michel Revest, Sandy Fabre