Patents by Inventor Sandya Narayanswami

Sandya Narayanswami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolation of biological materials
    Patent number: 5665582
    Abstract: A method for the isolation and sorting of biological materials has been developed. Biological material includes chromosomes, segments of chromosomes, cell organelles, or other minute cellular components. The biological material is separated from the cellular milieu, if necessary, and anchored to a support. Examples of a support are glass coverslips, glass or polymer beads. The anchoring is by means of a reversible polymer and cross-linking system. The supported biological material may then be labelled with compositions capable of binding to said material, and with magnetic particles. Examples of the binding material include nucleic acid probes and antibodies. An example of the antibodies would be those directed to histones. Other labels, for example, fluorescein-biotin-avidin may be used. The material may be released from the support and sorted by a magnetic force.
    Type: Grant
    Filed: April 18, 1994
    Date of Patent: September 9, 1997
    Assignee: Dekalb Genetics Corp.
    Inventors: Albert P. Kausch, Sandya Narayanswami
  • Isolation of biological materials using magnetic particles
    Patent number: 5508164
    Abstract: A method for the isolation and sorting of biological materials has been developed. Biological material includes chromosomes, segments of chromosomes, cell organelles, or other minute cellular components. The biological material is separated from the cellular milieu, if necessary, and anchored to a support. Example of a support are glass coverslips, glass or polymer beads. The anchoring is by means of a reversible cross-linking system. The supported biological material is then labelled with compositions capable of binding to said material, and with magnetic particles. Examples of the binding material include nucleic acid probes and antibodies. An example of the antibodies would be those directed to histones. Other labels, for example, fluoresceinbiotin-avidin may be used. The material may be released from the support and sorted by a magnetic force.
    Type: Grant
    Filed: October 29, 1993
    Date of Patent: April 16, 1996
    Assignee: Dekalb Genetics Corporation
    Inventors: Albert P. Kausch, Sandya Narayanswami, Jerry E. Manning, Barbara A. Hamkalo