Patents by Inventor Sanford Simon

Sanford Simon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190254945
    Abstract: The present invention provides a method of treating a subject afflicted with hyperpigmentation or of lightening the skin tone of a subject comprising administering to the subject an amount of a compound having the structure: or a salt or ester thereof, so as to thereby treat the subject or lighten the skin tone of the subject.
    Type: Application
    Filed: May 3, 2019
    Publication date: August 22, 2019
    Applicant: The Research Foundation for The State University of New York
    Inventors: Shilpi GOENKA, Sanford SIMON
  • Patent number: 10300000
    Abstract: The present invention provides a method of treating a subject afflicted with hyperpigmentation or of lightening the skin tone of a subject comprising administering to the subject an amount of a compound having the structure: or a salt or ester thereof, so as to thereby treat the subject or lighten the skin tone of the subject.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: May 28, 2019
    Assignee: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Shilpi Goenka, Sanford Simon
  • Publication number: 20180071187
    Abstract: The present invention provides a method of treating a subject afflicted with hyperpigmentation or of lightening the skin tone of a subject comprising administering to the subject an amount of a compound having the structure: or a salt or ester thereof, so as to thereby treat the subject or lighten the skin tone of the subject.
    Type: Application
    Filed: September 12, 2017
    Publication date: March 15, 2018
    Inventors: Shilpi GOENKA, Sanford SIMON, Francis JOHNSON
  • Publication number: 20170065534
    Abstract: The present invention relates, generally, to compositions comprising at least one antigen encapsulated within at least one fibrous polymer matrix and their use in intradermal vaccine delivery. It has been discovered that the intradermal delivery of antigens into the antigenpresenting cell-rich layers of the skin requires less antigen than traditional vaccine delivery methods and is still capable of eliciting an immune response comparable to that observed with traditional vaccine delivery methods.
    Type: Application
    Filed: May 1, 2015
    Publication date: March 9, 2017
    Applicant: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Katarzyna SAWICKA, Sanford SIMON
  • Publication number: 20070015738
    Abstract: The invention relates to a method for inhibiting bacterial spores from becoming infectious vegetative cells in a mammal in need thereof. The method comprises administering to the mammal an effective amount of a non-antibacterial tetracycline formulation. In one embodiment, the non-antibacterial tetracycline formulation comprises an antibacterial tetracycline in a sub-antibacterial amount. In another embodiment, the non-antibacterial tetracycline formulation comprises a non-antibacterial tetracycline.
    Type: Application
    Filed: July 15, 2005
    Publication date: January 18, 2007
    Inventors: Stephen Walker, Lorne Golub, Sanford Simon
  • Publication number: 20070015739
    Abstract: The invention relates to a method for inhibiting bacterial spores from becoming infectious vegetative cells in a mammal in need thereof. In another embodiment, invention relates to a method for inhibiting outgrowth of bacterial spores in a mammal in need thereof. The method comprises administering to the mammal an effective amount of a non-antibacterial tetracycline formulation. In one embodiment, the non-antibacterial tetracycline formulation comprises an antibacterial tetracycline in a sub-antibacterial amount. In another embodiment, the non-antibacterial tetracycline formulation comprises a non-antibacterial tetracycline.
    Type: Application
    Filed: December 23, 2005
    Publication date: January 18, 2007
    Inventors: Stephen Walker, Lorne Golub, Sanford Simon
  • Publication number: 20060288430
    Abstract: Genetically-modified mammals and immune cells are provided which are capable of producing or secreting detectably-labeled immunoglobulin molecules as a result of genetic modifications of at least one immunoglobulin gene in the genome thereof, such that a fusion polynucleotide encoding a detectable protein or peptide and an immunoglobulin component molecule is present.
    Type: Application
    Filed: June 23, 2006
    Publication date: December 21, 2006
    Inventors: Sanford Simon, Yu Chen
  • Publication number: 20060277974
    Abstract: An apparatus is for detecting the presence of selected gaseous compounds indicative of a medical condition includes a probe having one or more sensor elements having a conductivity which is responsive to the presence of selected gaseous compounds, at least one sensor element containing a transition metal oxide selected from the group consisting of WO3, beta-MoO3 and UO2; and means for measuring the conductivity of each said sensor element.
    Type: Application
    Filed: February 9, 2006
    Publication date: December 14, 2006
    Applicant: The Research Foundation of State University of New York
    Inventors: Pelagia-Irene Gouma, Sanford Simon
  • Publication number: 20060063674
    Abstract: A fertilizer spike, in an exemplary embodiment, includes particulate fertilizer source material compacted together under pressure in a die to form a substantially wedged shaped spike body. The spike is configured to be hammered into a terrain such that the spike remains substantially intact. At least a portion of the fertilizer source materials are releasable into the terrain through microbial action. The fertilizer spike is substantially free of a thermoset binder material.
    Type: Application
    Filed: September 23, 2004
    Publication date: March 23, 2006
    Inventors: Robert Morris, Sanford Simon
  • Publication number: 20050148552
    Abstract: A method of treating eczema in a human or other mammal in need thereof comprising administering systemically to said human or other mammal a tetracycline compound in an amount that is effective to treat eczema, but has substantially no antibacterial activity.
    Type: Application
    Filed: November 5, 2004
    Publication date: July 7, 2005
    Inventors: Maria Ryan, Yu Liu, Lorne Golub, Hsi-Ming Lee, Sanford Simon, Stephen Walker
  • Patent number: 6429204
    Abstract: The invention is a method of inhibiting a sarcoma, such as Kaposi's sarcoma, in a mammal. The method employs 6-demethyl-6-deoxy-4-de(dimethylamino)tetracycline (CMT-3.
    Type: Grant
    Filed: April 3, 2000
    Date of Patent: August 6, 2002
    Assignee: University of Miami
    Inventors: Lorne M. Golub, Thomas F. McNamara, Nungavaram S. Ramamurthy, Hsi-Ming Lee, Sanford Simon, Balakrishna L. Lokeshwar, Marie G. Selzer, Norman L. Block
  • Patent number: 6100248
    Abstract: The invention is a method of inhibiting cancer growth, by inhibiting cellular proliferation, invasiveness, or metastasis, or by inducing cytotoxicity against cancer in mammals. The method employs 6-demethyl-6-deoxy-4-de(dimethylamino)tetracycline (CMT-3) and other functionally related chemically modified, preferably non-antibacterial, tetracycline compounds to inhibit cancer growth. The method is particularly effective to inhibit the establishment, growth, and metastasis of solid tumors, such as tumors derived from colon cancer cells, breast cancer cells, melanoma cells, prostatic carcinoma cells, or lung cancer cells.
    Type: Grant
    Filed: January 15, 1998
    Date of Patent: August 8, 2000
    Inventors: Lorne M. Golub, Thomas F. McNamara, Nungavaram S. Ramamurthy, Hsi-Ming Lee, Sanford Simon, Balakrishna L. Lokeshwar, Marie G. Selzer, Norman L. Block
  • Patent number: 5977091
    Abstract: The invention discloses a novel method for preventing acute lung injury in a mammal following trauma. The method includes treating the mammal with an effective amount of a tetracycline prior to intrapulmonary accumulation of neutrophils.
    Type: Grant
    Filed: September 21, 1998
    Date of Patent: November 2, 1999
    Assignee: The Research Foundation of State University of New York
    Inventors: Gary Nieman, Anthony Picone, Charles Lutz, David Carney, Louis Gatto, Lorne M. Golub, Sanford Simon, Nungavarm S. Ramamurthy
  • Patent number: 5837696
    Abstract: The invention is a method of inhibiting cancer growth, including cellular proliferation, invasiveness, or metastasis in mammals. The method employs 6-demethyl-6-deoxy-4-dedimethylaminotetracycline (CMT-3) and other functionally related chemically modified, preferably non-antibacterial, tetracycline compounds to inhibit cancer growth. The method is particularly effective to inhibit the establishment, growth, and metastasis of solid tumors, such as tumors derived from colon cancer cells, breast cancer cells, melanoma cells, prostatic carcinoma cells, or lung cancer cells.
    Type: Grant
    Filed: January 15, 1997
    Date of Patent: November 17, 1998
    Assignees: The Research Foundation of State University of New York, University of Miami
    Inventors: Lorne M. Golub, Thomas F. McNamara, Nungavaram S. Ramamurthy, Hsi-Ming Lee, Sanford Simon, Balakrishna L. Lokeshwar, Marie G. Selzer, Norman L. Block