Abstract: The present invention provides solid dispersion, comprising: 20-O-?-D-glucopyranosyl-20(S)-protopanaxadiol which is a pharmacologically active ingredient; and a saturated polyglycolized glyceride which is a lipid matrix. The solid dispersion of the present invention has effects of increasing dissolution rate of 20-O-?-D-glucopyranosyl-20(S)-protopanaxadiol.

Abstract: Disclosed relates to a transdermal patch comprising paroxetine that is useful to reduce the side effects accompanied with the initial high drug concentration after oral administration of paroxetine and decrease the broad metabolism of the drug in the liver. Moreover, the transdermal patch comprising paroxetine of the present invention has an excellent skin permeation rate and shows high bioavailability compared with oral administration of the drug.

Abstract: Disclosed herein is a hair growth-stimulating composition containing a non-polar solvent-soluble extract fraction of Cantharis as an active ingredient. The composition shows an excellent hair growth activity with minimal skin irritation compared to conventional ones. It can be used for hair growth in various fields, including medical and non-medical supplies and cosmetics.

Abstract: The present invention relates to a composition comprising itraconazole for oral administration, more precisely, a composition for oral administration containing 1 part by weight itraconazole, 0.1-0.5 part by weight citric acid and 0.1-0.5 part by weight hydroxypropylmethylcellulose. The composition of the present invention has the advantages of mitigating discomfort of administration by reducing the amount of the additives used to make itraconazole water-soluble, lowering the production price by shortening processing time of spray-drying, high solubility and dissolution rate, excellent reproducibility and stability.

Abstract: The present invention relates to a composition of topical preparation containing alprostadil alkyl ester, and more particularly, comprising an alprostadil alkyl ester, an oily vehicle, a skin permeation enhancer and an anti-irritant agent.

Abstract: The present invention relates to a novel parenteral composition comprising propofol and electrokinetic stabilizer.

Abstract: The present invention relates to a composition of topical preparation containing alprostadil alkyl ester, and more particularly, comprising an alprostadil alkyl ester, an oily vehicle, a skin permeation enhancer and an anti-irritant agent.

Abstract: The present invention relates to a composition of topical preparation containing alprostadil, which has excellent skin permeation rate with little skin irritation, which is prepared by dissolving alprostadil or a solid dispersion thereof prepared using poloxamer, into a mixture of an oily vehicle, a pyrrolidone and an anti-irritant agent.

Abstract: Transdermal gels comprising (1) ketoprofen as an effective component, (2) poloxamer, (3) one or more agents selected from ethyl alcohol, isopropyl alcohol, propylene glycol, polyethylene glycol and glycerin, (4) one or more agents selected from the group consisting of lauric acid, oleic acid, capric acid, myristic acid, lauryl alcohol, oleyl alcohol and menthol, (5) water or a buffer solution. The gels form thin and pliable films, which are easily washable with water. They possess prolonged antiinflammatory and analgesic activities and physicochemical stability with less systemic side effects and gastric irritation.