Abstract: The present invention relates to an Impatiens balsamina-derived anti-bacterial peptide and an anti-bacterial composition comprising same. Specifically, six types of peptide derivatives were prepared on the basis of the sequence of a conventional Impatiens balsamina-derived peptide Ib-AMP4 known to have anti-fungal activity, and a peptide derivative exhibiting anti-bacterial and anti fungal activity better than that of Ib-AMP4 and having weak cytotoxicity and hemolytic properties has been identified, and thus the peptide derivative, which is an Impatiens balsamina-derived anti-bacterial peptide, can be used, in the fields of medicine, cosmetics and food, as an anti-bacterial or anti-fungal pharmaceutical composition, antibiotic, food preservative, cosmetic preservative, pharmaceutical preservative or feed additive preservative, and the like.

Abstract: Disclosed are a hyaluronic acid derivative effective against atopic dermatitis, and a method for manufacturing same. The method for manufacturing the hyaluronic acid derivative of the present invention comprises: a first step of chlorinating ascorbic acid; a second step of producing a tetrabutylamonium hydroxide (TBA) salt of hyaluronic acid; and a third step of conjugating the ascorbic acid chlorinated in the first step and the TBA salt of hyaluronic acid produced in the second step. The hyaluronic acid derivative can effectively decrease the substances causing skin lesions, can contribute toward the remission of atopic disease, and is effective in skin renewal.