Abstract: The present invention relates to a drug delivery vehicle comprising a polydiacetylene liposome, wherein a lipid bilayer is formed by a mixture of 10,12-pentacosadiynoic acid (PCDA), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE), and N-palmitoyl homocysteine (PHC), and a drug to be delivered is encapsulated in an isolated inner space of a polydiacetylene liposome. The PDA liposome drug delivery vehicle of the present invention comprises a lipid layer formed by mixing different phospholipids, excluding polydiacetylene, so as to be stable, and thus any leakage problems of an encapsulated drug are eliminated. In addition, since the liposome is sensitive to a pH, the shape and size thereof can be readily changed through the formation of a liposome-liposome conjugate by the improved sensitivity of the drug delivery vehicle under a specific acidic requirement, thereby enabling selective drug release, and thus can be applied as a drug delivery vehicle for various target materials.

Abstract: Provided are a neural adaptive learning device using question types and relevant concepts and a learning method using the same, the device being capable of: storing curriculum, chapters, question types, problem types, problems, concepts and a relationship between the concepts; providing learning content to a user by using the stored data; connecting a learning history of each user for each problem in association with a chapter, a question type, a problem type and one or more concepts so as to extract a problem to be provided to a user by a neural adaptive method according to a rule defined for each of a plurality of learning levels on the basis of a mutually connected structure; adjusting the priority of a plurality of question types; and providing a concept cloud map for learning.

Abstract: Provided are a neural adaptive learning device and a neural adaptive learning method using a relational concept map, which: store problems for learning, concepts related to the problems, and relations among the concepts; provide a cloud map as a relational concept map to a user by utilizing the problems, the concepts, the concept map, and the learning history; relate and connect the learning history with the problems and one or more concepts; enable the extraction of the concept selected by the user and searching for the desired concept of the user; provide the cloud map for a user equipment of the user by using the extracted concept and the related concept; and extract the connected problems from a problem storage unit to enable learning.

Abstract: The present invention relates to a drug delivery vehicle comprising a polydiacetylene liposome, wherein lipid bilayer is formed by a mixture of 10,12-pentacosadiynoic acid (PCDA), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE), and N-palmitoyl homocysteine (PHC), and a drug to be delivered is encapsulated in an isolated inner space of a polydiacetylene liposome. The PDA liposome drug delivery vehicle of the present invention comprises a lipid layer formed by mixing different phospholipids, excluding polydiacetylene, so as to be stable, and thus any leakage problems of an encapsulated drug are eliminated. In addition, since the liposome is sensitive to a pH, the shape and size thereof can be readily changed through the formation of a liposome-liposome conjugate by the improved sensitivity of the drug delivery vehicle under a specific acidic requirement, thereby enabling selective drug release, and thus can be applied as a drug delivery vehicle for various target materials.