Abstract: The present invention relates to a bi-specific antibody that specifically binds to alpha-synuclein and IGF1R, and an use of the bi-specific antibody for the prevention, treatment and/or diagnosis of synucleinopathies associated with alpha-synuclein or alpha-synuclein aggregates, and can allow the alpha-synuclein antibody or an antigen-binding fragment thereof to penetrate the blood brain barrier to exert its action in the brain, and extend the half-life to maintain the efficacy for a long time.

Abstract: An NFC-enabled apparatus is disclosed. The apparatus includes a touch screen display and a near field communication (NFC) module comprising an NFC antenna and an NFC controller. In response to tagging between the NFC-enabled apparatus and the external NFC terminal, an NFC communication channel is established between the NFC-enabled apparatus and the external NFC terminal for data communication therebetween.

Abstract: The present disclosure relates to a novel PLK1 degradation inducing compound having a structure according to Formula I, a method for preparing the same, and the use thereof. The compounds of the present disclosure exhibit an effect of inducing PLK1 degradation. Therefore, the compounds of the present disclosure may be effectively utilized for preventing or treating PLK1-related diseases.

Abstract: A method for providing information on a user's concept understanding is provided. The method includes acquiring a set of data on a user's understanding of concepts including a first concept estimated using a concept-specific understanding estimation model that is trained on the basis of concept-specific correctness/incorrectness sequence data, estimating the user's understanding of a second concept not encountered by the user using a matrix factorization algorithm on the concept-specific correctness/incorrectness sequence data represented in a matrix structure with respect to the first concept and the second concept, and visualizing the user's understanding of the first concept included in the acquired data set and the second concept on a device of the user. The concept-specific understanding estimation model is trained such that the concept understanding is estimated by assigning a greater weight to a piece of the concept-specific correctness/incorrectness sequence data generated at a later time point.

Abstract: The present disclosure relates to a photo-curable composition, a cured product thereof, and an optical member and a display device comprising same. The photo-curable composition has excellent low refractive index, light transmittance, and low haze characteristics by comprising a first olefinic monomer containing fluorine, a second olefinic monomer having an absolute viscosity of 7 cP or less at 25° C., a photo-polymerization initiator, and an amine compound.

Abstract: Disclosed herein is a method of depositing a transition metal single-atom catalyst including preparing a carbon carrier, and depositing a transition metal single-atom catalyst on the carbon carrier, in which the carbon carrier is surface-treated by an oxidation process, and wherein the deposition is carried out by an arc plasma process.

Abstract: A semiconductor device includes a first semiconductor layer having first and second regions, a plurality of first channel layers spaced apart from each other in a vertical direction on the first region of the first semiconductor layer, a first gate electrode surrounding the plurality of first channel layers, a plurality of second channel layers spaced apart from one another in the vertical direction on the second region of the first semiconductor layer, and a second gate electrode surrounding the plurality of second channel layers, wherein each of the plurality of first channel layers has a first crystallographic orientation, and each of the plurality of second channel layers has a second crystallographic orientation different from the first crystallographic orientation, and wherein a thickness of each of the plurality of first channel layers is different from a thickness of each of the plurality of second channel layers.

Abstract: The present disclosure provides an apparatus and method for encoding a video with ultra-low latency, the apparatus including: one or a plurality of video sources configured to provide a video signal; an encoder configured to encode the video signal provided through the video source and provided for each of the video sources; and a caster configured to transmit video data encoded by the encoder to the outside through a network communication network. Accordingly, the present disclosure can transmit a video with ultra-low latency, so a video service is possible in real time anytime anywhere as long as the internet is connected, whereby there is the advantage that the present disclosure can be applied to various fields of 4th industry such as autonomous driving, unmanned drone operation, driving of unmanned heavy equipment, robot control, a remote medical service, VR/AR, an intelligent CCTV, a smart city?factory, provision of traffic information, etc.

Abstract: Provided is an organic light emitting device comprising an anode; a cathode; and a light emitting layer therebetween, the light emitting layer comprising a compound of Chemical Formula 1 and a compound of Chemical Formula 2, the device having improved driving voltage, efficiency and lifetime: wherein: any one of R?1 to R?12 is Chemical Formula 3, and the rest are hydrogen or deuterium: Ar1, Ar2, Ar?1, and Ar?2 are each independently a substituted or unsubstituted C6-60 aryl or C2-60 heteroaryl containing any one or more of N, O and S; R1 is hydrogen, deuterium, or a substituted or unsubstituted C6-60 aryl or C2-60 heteroaryl containing any one or more of N, O and S; and the other substituents are as defined in the specification.

Abstract: A freight vehicle on which a drone is docked, may include: a transfer device provided in the vehicle and configured to move up and down between an internal space of the vehicle and a roof to receive freight from the drone through the roof of the vehicle or transfer freight to the drone; and a loadspace separated, as a portion of the internal space of the vehicle, from a space where the transfer device is provided and including an open portion formed on a side or a rear of the vehicle, and onto which the freight is loaded.

Abstract: The present disclosure relates to a method for preparing a mordenite zeolite, the method including crystallizing, at a temperature of 150° C. to 190° C., a gel which includes, in mol based on 1 mol of silica, 0.02 to 0.2 of an alumina precursor, 0.01 to 0.04 of a structure-directing agent, 0.1 to 0.18 of a pH control agent, and 10 to 100 of water. According to the present disclosure, a mordenite zeolite having high particle size uniformity and a particle size controllable while maintaining the particle size uniformity may be prepared.

Abstract: A compound represented by Chemical Formula 1 and an organic light emitting device including the same are provided. The compound is used as a material for an organic material layer of the organic light emitting device, and provides improved efficiency, low driving voltage, and increased lifespan of the organic light emitting device.

Abstract: The present disclosure provides a seat cushion extension device for a fold-and-dive seat. The seat cushion extension device may include a pair of seat cushion side frames arranged at a predetermined interval, a seatback frame rotatably connected to the pair of seat cushion side frames and having a guide pin formed on an outer surface thereof, a seat cushion frame, a pair of links rotatably connected between the pair of seat cushion side frames and a front end of the seat cushion frame, and a pair of extension frames. Each of the pair of extension frames may have a front end connected to the seat cushion frame, and a rear end formed with a guide hole, into which a guide pin may be inserted. The seat cushion extension device may facilitate a forward extension of a seat cushion regardless of a position of a seatback of the fold-and-dive seat.

Abstract: An apparatus of tilting a seat cushion of a vehicle, includes a tilting motor, a pinion gear, a sector gear, and a tilting link which perform the tilting operation of the seat cushion and exert a binding force in a tilted state of the seat cushion and are provided to be connected to both of one side and the other side of a seat cushion frame, and has two sector gears positioned on left and right sides and connected to each other by a connection bar so that, by strengthening a binding force of the front portion of the seat cushion, it is possible to secure the safety of passengers in the event of a collision.

Abstract: A method for providing a correctness/incorrectness prediction for a learning question is provided. The method includes the steps of: acquiring a set of data including a user variable determined on the basis of concept-specific correctness/incorrectness sequence data of at least one user, and at least one variable related to a question and a concept associated with the user variable; and calculating a probability that a first user corresponding to a specific user variable correctly answers a first question corresponding to a specific concept, with reference to the data set.

Abstract: An operating method of a memory device, comprising: entering self-refresh section, updating a counting code by counting an edge of a reference cycle signal, first activating an operation control signal for the self-refresh section when a temperature application code has an initialized value in response to the counting code, updating the temperature application code after the operation control signal is first activated, second activating the operation control signal in response to the counting code based on the updated temperature application code, exiting from the self-refresh section, and initializing the counting code and the temperature application code.

Abstract: Provided is an organic light-emitting device having improved driving voltage, efficiency and lifespan, the device comprising an anode, a cathode, and a light emitting layer including a light emitting layer that includes a compound of Chemical Formula 1 and a compound of Chemical Formula 2 between the anode and the cathode: where Ar1 and Ar2 are each independently a substituted or unsubstituted C6-60 aryl or C2-60 heteroaryl containing at least one of N, O and S; R1 is each independently hydrogen or deuterium; R2 to R6 and R9 to R11 are each independently hydrogen or deuterium; one of R7 and R8 is ?and the other is hydrogen or deuterium; Ar3 and Ar4 are each independently a substituted or unsubstituted C6-60 aryl or C2-60 heteroaryl containing at least one of N, O and S; and the other substituents are as defined in the specification.

Abstract: The present invention relates to electrode slurry coating apparatus and method, the present invention ultimately allowing the process efficiency to be increased and rate of errors to be reduced when double-layer structured active material layers are formed by temporally adjusting the height of first and second discharge outlets through which active material is discharged.

Abstract: The present disclosure relates to a positive active material for a lithium rechargeable battery, a manufacturing method thereof, and a lithium rechargeable battery including the positive active material, and it provides a positive active material which is a lithium composite metal oxide including nickel, cobalt, and manganese, and either has orientation in a direction of with respect to an ND axis that is equal to or greater than 29% or has orientation in a direction of [120]+[210] with respect to an RD axis that is equal to or greater than 82% in the case of an EBSD analysis with a misorientation angle (?g) that is equal to or less than 30 degrees.

Abstract: Provided are a pulse compressor and a two-photon excited fluorescence microscope. The microscope includes a light source which generates a laser beam having a pulse, a pulse compressor which compresses the pulse of the laser beam, an objective lens which provides the laser beam to a specimen, and image sensors which receive the laser beam and obtain images of the specimen. The pulse compressor may include a grating plate, a corner cube provided on one side of the grating plate, and a retroreflector provided on the other side of the grating plate.