Abstract: An embodiment of the invention is an interproximal brush with gargle and disinfectant. This interproximal brush includes two brush units. The brush units each consists of a handle having a rectangular cross-section, and an interproximal cleaning means, such as bristles or a dental floss, fixed to an end of the handle. The interproximal brush also has a casing consisting of two reception parts. In this case, the reception parts have a hollow box shape for receiving the brush units, and contain gargle and disinfectant therein, respectively. Further, a sealing unit is provided at a position around a mouth of each of the two reception parts.

Abstract: An embodiment of the invention is an interproximal brush with gargle and disinfectant. This interproximal brush includes two brush units. The brush units each consists of a handle having a rectangular cross-section, and an interproximal cleaning means, such as bristles or a dental floss, fixed to an end of the handle. The interproximal brush also has a casing consisting of two reception parts. In this case, the reception parts have a hollow box shape for receiving the brush units, and contain gargle and disinfectant therein, respectively. Further, a sealing unit is provided at a position around a mouth of each of the two reception parts.

Abstract: A new casein is disclosed isolated from the milk of Korean cattle with a &bgr;-casein A1H genotype. Amino acid sequence analysis of the casein revealed a length of 209 amino acids, where, in comparison to the more conventional &bgr;-casein variant A2, at amino acid position 25, Arg is replaced by Cys, at position 88, Leu is replaced by Ile, at position 117, Gln is replaced by Glu, at position 175, Glu is replaced by Gln, and at position 195, Gln is replaced by Glu. The new casein variant disclosed can be mass produced by the selective breeding of individual bovines to produce large quantities of milk containing the new casein variant. In one example of such breeding, a female calf was born that subsequently produced the inventive casein at a yield of 4.5 kg per day. The new casein gene can be detected DNA hybridization analysis in bovines secreting the new casein.

Abstract: The present invention relates to a purified casein phosphopeptide(CPP) having a novel amino acid sequence and a purified casein including same wherein the 25th Arg from N-terminal in a conventional CPP is replaced by Cys, rendering the CPPs to forming a dimer by disulfide bond. In the corresponding DNA sequence, cytosine is replaced by thymine to cause the amino acid replacement from Arginine(Arg) to Cysteine(Cys). The CPP or the casein containing same has an improved ability of solubilizing minerals and absorbing thereof in animals. The CPP or the beta-casein H containing same can be added to foodstuffs, beverages, medication, cosmetics, feed in an effective amount of enhancing a mineral absorption in animals. An oral composition comprising the beta-casein H or the inventive CPP and a pharmaceutically acceptable carrier can reduce or relieve a dentinal hypersensitivity.