Patents by Inventor Sang-Ku Yoo

Sang-Ku Yoo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR SYNTHESIZING 2-((6-(HYDROXYMETHYL)CHROMENE-5-YL)OXY)-1-PHENYLETHANONE DERIVATIVE
    Publication number: 20220298170
    Abstract: The present invention relates to a method for synthesizing a 2-((6-(hydroxymethyl)chromen-5-yl)oxy)-1-phenylethanone derivative. When the method is used, it is possible to effectively synthesize a 2-((6-(hydroxymethyl)chromene-5-yl)oxy)-1-phenylethanone derivative.
    Type: Application
    Filed: July 20, 2020
    Publication date: September 22, 2022
    Inventors: Sang Ku YOO, Ji Young KIM, Jung Woo LEE, Jeong Ho LIM, Ku Suk KANG, Jin Young KIM
  • Catalyst for asymmetric hydrogenation of compound containing carbon double bond
    Patent number: 11420988
    Abstract: The present invention may provide an asymmetric hydrogenation catalyst capable of resolving enantiomers with excellent enantioselectivity from a carbon-carbon double bond-containing compound. The catalyst according to one embodiment of the present invention includes: an iridium cation; and a ligand bonded to the iridium cation.
    Type: Grant
    Filed: October 2, 2019
    Date of Patent: August 23, 2022
    Assignee: GLACEUM, INC.
    Inventors: Sang Ku Yoo, Ku Suk Kang, Jin Young Kim, Jung Woo Lee, Ji Young Kim, Jeong Ho Im
  • Method for synthesizing 3-phenyl-2,8-dihydropyrano [2,3-f] chromene derivative
    Patent number: 11420978
    Abstract: The present invention relates to a method for synthesizing a 3-phenyl-2,8-dihydropyrano[2,3-f]chromene derivative, which may be usefully used for synthesizing a pyranochromenyl phenol derivative, and when the derivative is used, the 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative may be effectively prepared.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: August 23, 2022
    Inventors: Sang Ku Yoo, Jin Wook Chung, In Geun Jo, Ji Young Kim, Jeong Ho Im, Ku Suk Kang, Jin Young Kim
  • PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROLOGICAL DISEASES
    Publication number: 20220257557
    Abstract: The present disclosure relates to a pharmaceutical composition for preventing or treating neurological disease containing a pyrano[2,3-f]chromene derivative compound, a pharmaceutically acceptable salt thereof, or a solvate thereof. The pharmaceutical composition is capable of enhancing or protecting the functions of various enzymes including paraoxonase.
    Type: Application
    Filed: February 28, 2020
    Publication date: August 18, 2022
    Inventors: SANG KU YOO, JI YOUNG KIM, IN GEUN JO, KYUNG IL KIM, YUN SUN PARK
  • Optically active pyranochromenyl phenol derivative and pharmaceutical composition comprising same
    Patent number: 11332475
    Abstract: The present invention relates to pyranochromenylphenol derivatives having different efficacies depending on the direction of optical activity and a pharmaceutical composition including the same, and in the pyranochromenylphenol derivatives, an R-enantiomer has excellent anti-diabetic efficacy by suppressing a rise in blood sugar and an S-enantiomer has excellent anti-obesity efficacy by suppressing an increase in body weight.
    Type: Grant
    Filed: December 8, 2020
    Date of Patent: May 17, 2022
    Inventors: Sang Ku Yoo, Jin Wook Chung, In Geun Jo, Ji Young Kim, Jeong Ho Im, Ku Suk Kang, Jin Young Kim
  • CATALYST FOR ASYMMETRIC HYDROGENATION OF COMPOUND CONTAINING CARBON DOUBLE BOND
    Publication number: 20210395282
    Abstract: The present invention may provide an asymmetric hydrogenation catalyst capable of resolving enantiomers with excellent enantioselectivity from a carbon-carbon double bond-containing compound. The catalyst according to one embodiment of the present invention includes: an iridium cation; and a ligand bonded to the iridium cation.
    Type: Application
    Filed: October 2, 2019
    Publication date: December 23, 2021
    Inventors: Sang Ku YOO, Ku Suk KANG, Jin Young KIM, Jung Woo LEE, Ji Young KIM, Jeong Ho IM
  • OPTICALLY ACTIVE PYRANOCHROMENYL PHENOL DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
    Publication number: 20210094967
    Abstract: The present invention relates to pyranochromenylphenol derivatives having different efficacies depending on the direction of optical activity and a pharmaceutical composition including the same, and in the pyranochromenylphenol derivatives, an R-enantiomer has excellent anti-diabetic efficacy by suppressing a rise in blood sugar and an S-enantiomer has excellent anti-obesity efficacy by suppressing an increase in body weight.
    Type: Application
    Filed: December 8, 2020
    Publication date: April 1, 2021
    Inventors: SANG KU YOO, JIN WOOK CHUNG, IN GEUN JO, Jl YOUNG KIM, JEONG HO IM, KU SUK KANG, JIN YOUNG KIM
  • 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and method for synthesizing optical isomer thereof
    Patent number: 10947250
    Abstract: The present invention relates to a method for synthesizing a 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and an optical isomer thereof, and an intermediate Compound which may be used for the synthesis method, and when the method and the intermediate Compound are used, the 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and the optical isomer thereof may be effectively synthesized.
    Type: Grant
    Filed: March 3, 2020
    Date of Patent: March 16, 2021
    Inventors: Sang Ku Yoo, Jin Wook Chung, In Geun Jo, Ji Young Kim, Jeong Ho Im, Ku Suk Kang, Jin Young Kim
  • METHOD FOR SYNTHESIZING 3-PHENYL-2,8-DIHYDROPYRANO [2,3-F] CHROMENE DERIVATIVE
    Publication number: 20210040106
    Abstract: The present invention relates to a method for synthesizing a 3-phenyl-2,8-dihydropyrano[2,3-f]chromene derivative, which may be usefully used for synthesizing a pyranochromenyl phenol derivative, and when the derivative is used, the 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative may be effectively prepared.
    Type: Application
    Filed: April 3, 2019
    Publication date: February 11, 2021
    Applicant: GLACEUM INC.
    Inventors: Sang Ku YOO, Jin Wook CHUNG, In Geun JO, Ji Young KIM, Jeong Ho IM, Ku Suk KANG, Jin Young KIM
  • 3-PHENYL-2,3,4,8,9,10-HEXAHYDROPYRANO[2,3-F]CHROMENE DERIVATIVE AND METHOD FOR SYNTHESIZING OPTICAL ISOMER THEREOF
    Publication number: 20200199142
    Abstract: The present invention relates to a method for synthesizing a 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and an optical isomer thereof, and an intermediate Compound which may be used for the synthesis method, and when the method and the intermediate Compound are used, the 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and the optical isomer thereof may be effectively synthesized.
    Type: Application
    Filed: March 3, 2020
    Publication date: June 25, 2020
    Inventors: SANG KU YOO, JIN WOOK CHUNG, IN GEUN JO, JI YOUNG KIM, JEONG HO IM, KU SUK KANG, JIN YOUNG KIM
  • Method for synthesizing 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2.3-f]chromene derivative and optical isomer of thereof
    Patent number: 10669282
    Abstract: The present invention relates to a method for synthesizing a 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and an optical isomer thereof, and an intermediate Compound which may be used for the synthesis method, and when the method and the intermediate Compound are used, the 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and the optical isomer thereof may be effectively synthesized.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: June 2, 2020
    Assignee: GLACEUM, INC.
    Inventors: Sang Ku Yoo, Jin Wook Chung, In Geun Jo, Ji Young Kim, Jeong Ho Im, Ku Suk Kang, Jin Young Kim
  • 3-PHENYL-2,3,4,8,9,10-HEXAHYDROPYRANO[2,3-F]CHROMENE DERIVATIVE AND METHOD FOR SYNTHESIZING OPTICAL ISOMER THEREOF
    Publication number: 20200048272
    Abstract: The present invention relates to a method for synthesizing a 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and an optical isomer thereof, and an intermediate Compound which may be used for the synthesis method, and when the method and the intermediate Compound are used, the 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and the optical isomer thereof may be effectively synthesized.
    Type: Application
    Filed: September 27, 2017
    Publication date: February 13, 2020
    Applicant: Glaceum, Inc.
    Inventors: Sang Ku YOO, Jin Wook CHUNG, In Geun JO, Ji Young KIM, Jeong Ho IM, Ku Suk KANG, Jin Young KIM
  • OPTICALLY ACTIVE PYRANOCHROMENYL PHENOL DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
    Publication number: 20190152984
    Abstract: The present invention relates to pyranochromenylphenol derivatives having different efficacies depending on the direction of optical activity and a pharmaceutical composition including the same, and in the pyranochromenylphenol derivatives, an R-enantiomer has excellent anti-diabetic efficacy by suppressing a rise in blood sugar and an S-enantiomer has excellent anti-obesity efficacy by suppressing an increase in body weight.
    Type: Application
    Filed: June 29, 2017
    Publication date: May 23, 2019
    Inventors: SANG KU YOO, JIN WOOK CHUNG, IN GEUN JO, Jl YOUNG KIM, JEONG HO IM, KU SUK KANG, JIN YOUNG KIM
  • Apparatus for generating 1-methylcyclopropene
    Patent number: 10010849
    Abstract: Provided is an apparatus for generating 1-methylcyclopropene. The apparatus of the present invention may enable the immediate and convenient generation of 1-methylcyclopropene in a desired location using stable 1-methylcyclopropene precursors.
    Type: Grant
    Filed: March 20, 2012
    Date of Patent: July 3, 2018
    Assignee: ERUM BIOTECHNOLOGIES, INC.
    Inventors: Sang Ku Yoo, Jin Wook Chung
  • Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease
    Patent number: 9783551
    Abstract: Provided are a pyranochromenyl phenol derivative, a pharmaceutically acceptable salt thereof, or a solvate thereof. Also provided is a pharmaceutical composition for preventing or treating metabolic syndrome or inflammatory disease comprising same. The present invention is efficacious in preventing or treating metabolic syndrome or inflammatory disease and is chemically stable.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: October 10, 2017
    Assignee: Glaceum Inc.
    Inventors: Sang Ku Yoo, Jin Wook Chung, In Geun Jo, Jeong Ho Im, Ku Suk Kang, Jin Young Kim
  • PYRANOCHROMENYL PHENOL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION FOR TREATING METABOLIC SYNDROME OR INFLAMMATORY DISEASE
    Publication number: 20160272650
    Abstract: Provided are a pyranochromenyl phenol derivative, a pharmaceutically acceptable salt thereof, or a solvate thereof. Also provided is a pharmaceutical composition for preventing or treating metabolic syndrome or inflammatory disease comprising same. The present invention is efficacious in preventing or treating metabolic syndrome or inflammatory disease and is chemically stable.
    Type: Application
    Filed: December 23, 2014
    Publication date: September 22, 2016
    Applicant: ERUM BIOTECHNOLOGIES, INC.
    Inventors: Sang Ku YOO, Jin Wook CHUNG, In Geun JO, Jeong Ho IM, Ku Suk KANG, Jin Young KIM
  • Cyclopropenes and method for applying cyclopropenes to agricultural products or crops
    Patent number: 9072293
    Abstract: Disclosed is a method for directly preparing in situ cyclopropenes for inhibiting ethylene action facilitating ripening and aging of plants via reaction of a cyclopropene precursor such as a compound of Formula (2) or Formula (3) with a fluoride (F?) and immediately applying the same to plants, and an aryl group-containing 1-alkylcyclopropene of Formula (6) effective for inhibiting the action of ethylene.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: July 7, 2015
    Assignee: Erum Biotechnologies Inc.
    Inventors: Sang-Ku Yoo, Jin Wook Chung
  • Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases
    Patent number: 9066922
    Abstract: Provided is a pharmaceutical composition for the treatment and prevention of obesity, diabetes, metabolic syndromes, degenerative diseases and mitochondrial dysfunction-related diseases, comprising: a therapeutically effective amount of a compound represented by Formula I below, or a pharmaceutically acceptable salt, prodrug, solvate or isomer thereof, and a pharmaceutically acceptable carrier, a diluent or an excipient, or any combination thereof. wherein R1 through R8 and n are as defined in this disclosure.
    Type: Grant
    Filed: April 25, 2013
    Date of Patent: June 30, 2015
    Assignees: MD BIOALPHA CO., LTD., KT & G CO., LTD.
    Inventors: Sang-Ku Yoo, Myunggyu Park, In Geun Jo, Taehwan Kwak
  • METHOD FOR CONTROLLING NAD(P)/NAD(P)H RATIO BY OXIDOREDUCTASE
    Publication number: 20140106387
    Abstract: Provided is a method capable of effectively treating various diseases associated with energy excess, such as obesity, diabetes, metabolic syndromes, degenerative diseases and mitochondrial dysfunction-related diseases, via elevation of an NAD(P)+/NAD(P)H ratio by increasing an NAD(P)+ concentration in vivo or in vitro through use of NAD(P)H as a substrate or coenzyme by oxidoreductase such as NAD(P)H:quinone oxidoreductase (NQO1), a method of screening a drug for the same and a therapeutic drug.
    Type: Application
    Filed: December 19, 2013
    Publication date: April 17, 2014
    Applicant: MD BIOALPHA CO., LTD.
    Inventors: Myung-Gyu PARK, Sang-Ku YOO, In Geun JO, Taehwan KWAK
  • APPARATUS FOR GENERATING 1-METHYLCYCLOPROPENE
    Publication number: 20140017134
    Abstract: Provided is an apparatus for generating 1-methylcyclopropene. The apparatus of the present invention may enable the immediate and convenient generation of 1-methylcyclopropene in a desired location using stable 1-methylcyclopropene precursors.
    Type: Application
    Filed: March 20, 2012
    Publication date: January 16, 2014
    Applicant: ERUM BIOTECHNOLOGIES, INC.
    Inventors: Sang Ku Yoo, Jin Wook Chung