Patents by Inventor Sang Kyu Nam

Sang Kyu Nam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing imatinib base
    Patent number: 9045456
    Abstract: A method for preparing an imatinib base includes reacting 4-(4-methyl-piperazinomethyl)-benzoic acid with a 2,2?-dibenzothiazolyl disulfide derivative in the presence of a phosphine derivative to prepare a novel thioester compound and preparing an imatinib base using the thioester compound as a reaction intermediate. With the method, imatinib base in higher yield and/or purity can be prepared cost-effectively.
    Type: Grant
    Filed: July 8, 2013
    Date of Patent: June 2, 2015
    Assignee: BCWORLD PHARM. CO., LTD.
    Inventors: Hearan Suh, Sang Kyu Nam, Jong Sun Lee, Seung Ki Kim
  • METHOD FOR PRODUCING IMATINIB BASE
    Publication number: 20130324726
    Abstract: A method for preparing an imatinib base includes reacting 4-(4-methyl-piperazinomethyl)-benzoic acid with a 2,2?-dibenzothiazolyl disulfide derivative in the presence of a phosphine derivative to prepare a novel thioester compound and preparing an imatinib base using the thioester compound as a reaction intermediate. With the method, imatinib base in higher yield and/or purity can be prepared cost-effectively.
    Type: Application
    Filed: July 8, 2013
    Publication date: December 5, 2013
    Inventors: Hearan Suh, Sang Kyu Nam, Jong Sun Lee, Seung Ki Kim
  • Method for producing imatinib base
    Patent number: 8563720
    Abstract: The present invention relates to a novel method for preparing an imatinib base, and more particularly to a method for preparing an imatinib base, which comprises reacting 4-(4-methyl-piperazinomethyl)-benzoic acid with a 2,2?-dibenzothiazolyl disulfide derivative in the presence of a phosphine derivative to prepare a novel thioester compound and preparing an imatinib base using the thioester compound as a reaction intermediate. In addition, the invention provides a novel thioester compound, which is used in the preparation of imatinib base, and a preparation method thereof. Ultimately, the invention provides a method of preparing the imatinib base in an economic manner and in high yield and purity and is expected to be used in the commercial production of large amounts of the imatinib base.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: October 22, 2013
    Assignee: BCWorld Pharm. Co., Ltd.
    Inventors: Hearan Suh, Sang Kyu Nam, Jong Sun Lee, Seung Ki Kim
  • METHOD FOR PRODUCING IMATINIB BASE
    Publication number: 20120330014
    Abstract: The present invention relates to a novel method for preparing an imatinib base, and more particularly to a method for preparing an imatinib base, which comprises reacting 4-(4-methyl-piperazinomethyl)-benzoic acid with a 2,2?-dibenzothiazolyl disulfide derivative in the presence of a phosphine derivative to prepare a novel thioester compound and preparing an imatinib base using the thioester compound as a reaction intermediate. In addition, the invention provides a novel thioester compound, which is used in the preparation of imatinib base, and a preparation method thereof. Ultimately, the invention provides a method of preparing the imatinib base in an economic manner and in high yield and purity and is expected to be used in the commercial production of large amounts of the imatinib base.
    Type: Application
    Filed: May 30, 2012
    Publication date: December 27, 2012
    Applicant: BCWORLD PHARM. CO., LTD.
    Inventors: Hearan Suh, Sang Kyu Nam, Jong Sun Lee, Seung Ki Kim