Patents by Inventor Sang-Oh AHN

Sang-Oh AHN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12012619
    Abstract: An NADPH-regeneration system based on monomeric isocitrate dehydrogenase (IDH) and a use thereof. Specifically, the present invention relates to a recombinant vector including a polynucleotide encoding an isocitrate dehydrogenase recombinant protein derived from Corynebacterium glutamicum (CgIDH) and an isocitrate dehydrogenase recombinant protein derived from Azotobacter vinelandii (AvIDH), a method for producing the recombinant protein, and an NADPH-regeneration system using the recombinant protein produced by the method. The enzyme in a monomeric form that may be efficiently used in the NADPH-regeneration system in the transformant into which the recombinant vector was introduced, was found, and the NADPH-regeneration system using the enzyme in a monomeric form has a very high utility value as biological parts and biocatalyst materials that provides NADPH to the NADPH-dependent enzyme.
    Type: Grant
    Filed: November 11, 2022
    Date of Patent: June 18, 2024
    Assignee: INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY
    Inventors: Geun Joong Kim, Hun-Dong Lee, Su-Kyoung Yoo, Dae Eun Cheong, Chul-Ho Yun, Hye-Ji Choi, Sang-Oh Ahn
  • Publication number: 20230143972
    Abstract: An NADPH-regeneration system based on monomeric isocitrate dehydrogenase (IDH) and a use thereof. Specifically, the present invention relates to a recombinant vector including a polynucleotide encoding an isocitrate dehydrogenase recombinant protein derived from Corynebacterium glutamicum (CgIDH) and an isocitrate dehydrogenase recombinant protein derived from Azotobacter vinelandii (AvIDH), a method for producing the recombinant protein, and an NADPH-regeneration system using the recombinant protein produced by the method. The enzyme in a monomeric form that may be efficiently used in the NADPH-regeneration system in the transformant into which the recombinant vector was introduced, was found, and the NADPH-regeneration system using the enzyme in a monomeric form has a very high utility value as biological parts and biocatalyst materials that provides NADPH to the NADPH-dependent enzyme.
    Type: Application
    Filed: November 11, 2022
    Publication date: May 11, 2023
    Inventors: Geun Joong KIM, Hun-Dong LEE, Su-Kyoung YOO, Dae Eun CHEONG, Chul-Ho YUN, Hye-Ji CHOI, Sang-Oh AHN
  • Publication number: 20230119241
    Abstract: A method of expressing hydrophobin in a soluble form and a method of purifying hydrophobin, and more particularly, to a method of expressing a recombinant fusion protein including hydrophobin in a soluble form in a host cell and then purifying the expressed recombinant fusion protein are provided.
    Type: Application
    Filed: November 17, 2022
    Publication date: April 20, 2023
    Inventors: Geun Joong KIM, Dae Eun CHEONG, Ho-Dong LIM, Sang-Oh AHN, Sung Hwan YOU
  • Publication number: 20220267742
    Abstract: The present invention relates to an NADPH-regeneration system based on monomeric isocitrate dehydrogenase (IDH) and a use thereof. Specifically, the present invention relates to a recombinant vector including a polynucleotide encoding an isocitrate dehydrogenase recombinant protein derived from Corynebacterium glutamicum (CgIDH) and an isocitrate dehydrogenase recombinant protein derived from Azotobacter vinelandii (AvIDH), a method for producing the recombinant protein, and an NADPH-regeneration system using the recombinant protein produced by the method. In the present invention, the enzyme in a monomeric form that may be efficiently used in the NADPH-regeneration system in the transformant into which the recombinant vector was introduced, was found, and the NADPH-regeneration system using the enzyme in a monomeric form has a very high utility value as biological parts and biocatalyst materials that provides NADPH to the NADPH-dependent enzyme.
    Type: Application
    Filed: March 1, 2021
    Publication date: August 25, 2022
    Inventors: Geun Joong KIM, Hun-Dong LEE, Su-Kyoung YOO, Dae Eun CHEONG, Chul-Ho YUN, Hye-Ji CHOI, Sang-Oh AHN
  • Publication number: 20210363199
    Abstract: A method of expressing hydrophobin in a soluble form and a method of purifying hydrophobin, and more particularly, to a method of expressing a recombinant fusion protein including hydrophobin in a soluble form in a host cell and then purifying the expressed recombinant fusion protein are provided.
    Type: Application
    Filed: July 30, 2020
    Publication date: November 25, 2021
    Inventors: Geun Joong KIM, Dae Eun CHEONG, Ho-Dong LIM, Sang-Oh AHN