Patents by Inventor Sang Zin Choi

Sang Zin Choi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210283206
    Abstract: The present invention relates to a composition comprising the mixed extract of mulberry and Poria cocos peel for preventing, improving or treating neurodegenerative disorders. The mixed extract of mulberry and Poria cocos peel which is the active ingredients contained in the composition of the present invention, has a memory improving activity through inhibiting of acetylcholine esterase and a neuroprotective effects and neuron protection by inhibiting the formation of beta amyloid and tau phosphorylation and promoting NGF production. Thus, the present invention may be useful as a pharmaceutical composition for preventing or treating degenerative neurological diseases, or as a health food for the above purpose.
    Type: Application
    Filed: February 8, 2021
    Publication date: September 16, 2021
    Applicant: NeuroBo Pharmaceuticals, Inc.
    Inventors: Sang Zin CHOI, Mi Won SOHN, Hyo Sang GO, Ja Young RYU, Jin Seok JEONG, Song Hyen CHOI, Eun Jin KIM, Young Woong CHO, So Young KIM
  • Publication number: 20210128656
    Abstract: The present invention relates to a pharmaceutical composition and a food composition for preventing or ameliorating degenerative neurological disease comprising Poria cocos peel extract for preventing, or treating neurodegenerative disorders. Poria cocos peel extract which is the active ingredients contained in the composition of the present invention, has a memory ameliorating activity through inhibiting of acetylcholine esterase and a neuroprotective effect and neuron protection by inhibiting the formation of beta amyloid and tau phosphorylation and promoting NGF production. Thus, the present invention may be useful as a pharmaceutical composition for preventing or treating degenerative neurological diseases, or as a health food for the above purpose.
    Type: Application
    Filed: November 13, 2020
    Publication date: May 6, 2021
    Inventors: Sang Zin CHOI, Mi Won SOHN, Hyo Sang GO, Ja Young RYU, Jin Seok JEONG, Song Hyen CHOI, Eun Jin KIM, Young Woong CHO, So Young KIM
  • Publication number: 20210113648
    Abstract: Disclosed are a pharmaceutical composition and a health functional food for the prevention and treatment of diabetic peripheral neuropathy, comprising an herb extract of a mixture of 3.5:1 Dioscorea Rhizoma:Dioscorea nipponica (w/w). Having the ability to synergistically increase in vivo levels of nerve growth factor, compared to the extracts from the herbs alone or herb mixtures of other weight ratios, the mixed herb extract is effective for preventing the apoptosis of nerve cells and promoting nerve regeneration. Thus, it can be applied to pharmaceutical compositions and health functional foods preventive and curative of diabetic peripheral neuropathy.
    Type: Application
    Filed: September 30, 2020
    Publication date: April 22, 2021
    Applicant: DONG-A ST CO., LTD.
    Inventors: Soon-Hoe KIM, Mi-Won SON, Sang-Zin CHOI, Hye-Ju KIM, Ja-Young RYU, Sun-Yeou KIM
  • Patent number: 10946053
    Abstract: The present invention relates to a composition comprising the mixed extract of mulberry and Poria cocos peel for preventing, improving or treating neurodegenerative disorders. The mixed extract of mulberry and Poria cocos peel which is the active ingredients contained in the composition of the present invention, has a memory improving activity through inhibiting of acetylcholine esterase and a neuroprotective effects and neuron protection by inhibiting the formation of beta amyloid and tau phosphorylation and promoting NGF production. Thus, the present invention may be useful as a pharmaceutical composition for preventing or treating degenerative neurological diseases, or as a health food for the above purpose.
    Type: Grant
    Filed: March 16, 2020
    Date of Patent: March 16, 2021
    Assignee: NeuroBo Pharmaceuticals, Inc.
    Inventors: Sang Zin Choi, Mi Won Sohn, Hyo Sang Go, Ja Young Ryu, Jin Seok Jeong, Song Hyen Choi, Eun Jin Kim, Young Woong Cho, So Young Kim
  • Publication number: 20200397845
    Abstract: This invention relates to a pharmaceutical composition and a health functional food for preventing or improving neurodegenerative disorders comprising mixed herb extracts of Dioscorea Rhizoma and Dioscorea nipponica in a weight ratio of 3.5:1 (w/w). The herb extracts mixed Dioscorea Rhizoma and Dioscorea nipponica in a weight ratio of 3.5:1 have the synergetic effects on increasing the amount of nerve growth factor in vivo, increasing the neural cell proliferation, promoting the formation of neuritis and enhancing cognitive abilities. Thus, the herb extracts of the present invention may be used for a pharmaceutical composition and a health functional food for preventing or treating neurodegenerative disorders.
    Type: Application
    Filed: June 4, 2020
    Publication date: December 24, 2020
    Applicant: DONG-A-ST Co., Ltd.
    Inventors: Soon Hoe KIM, Mi-Won SON, Sang-Zin CHOI, Hye-Ju KIM, Ja-Young RYU, Sun-Yeou KIM
  • Patent number: 10864238
    Abstract: The present invention relates to a pharmaceutical composition and a food composition for preventing or ameliorating degenerative neurological disease comprising Poria cocos peel extract for preventing, or treating neurodegenerative disorders. Poria cocos peel extract which is the active ingredients contained in the composition of the present invention, has a memory ameliorating activity through inhibiting of acetylcholine esterase and a neuroprotective effect and neuron protection by inhibiting the formation of beta amyloid and tau phosphorylation and promoting NGF production. Thus, the present invention may be useful as a pharmaceutical composition for preventing or treating degenerative neurological diseases, or as a health food for the above purpose.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: December 15, 2020
    Assignee: NEUROBO PHARMACEUTICALS, INC.
    Inventors: Sang Zin Choi, Mi Won Sohn, Hyo Sang Go, Ja Young Ryu, Jin Seok Jeong, Song Hyen Choi, Eun Jin Kim, Young Woong Cho, So Young Kim
  • Patent number: 10813973
    Abstract: Disclosed are a pharmaceutical composition and a health functional food for the prevention and treatment of diabetic peripheral neuropathy, comprising an herb extract of a mixture of 3.5:1 Dioscorea Rhizoma:Dioscorea nipponica (w/w). Having the ability to synergistically increase in vivo levels of nerve growth factor, compared to the extracts from the herbs alone or herb mixtures of other weight ratios, the mixed herb extract is effective for preventing the apoptosis of nerve cells and promoting nerve regeneration. Thus, it can be applied to pharmaceutical compositions and health functional foods preventive and curative of diabetic peripheral neuropathy.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: October 27, 2020
    Assignee: DONG-A ST CO., LTD.
    Inventors: Soon-Hoe Kim, Mi-Won Son, Sang-Zin Choi, Hye-Ju Kim, Ja-Young Ryu, Sun-Yeou Kim
  • Publication number: 20200289594
    Abstract: The present invention relates to a composition comprising the mixed extract of mulberry and Poria cocos peel for preventing, improving or treating neurodegenerative disorders. The mixed extract of mulberry and Poria cocos peel which is the active ingredients contained in the composition of the present invention, has a memory improving activity through inhibiting of acetylcholine esterase and a neuroprotective effects and neuron protection by inhibiting the formation of beta amyloid and tau phosphorylation and promoting NGF production. Thus, the present invention may be useful as a pharmaceutical composition for preventing or treating degenerative neurological diseases, or as a health food for the above purpose.
    Type: Application
    Filed: March 16, 2020
    Publication date: September 17, 2020
    Applicant: NeuroBo Pharmaceuticals, Inc.
    Inventors: Sang Zin CHOI, Mi Won SOHN, Hyo Sang GO, Ja Young RYU, Jin Seok JEONG, Song Hyen CHOI, Eun Jin KIM, Young Woong CHO, So Young KIM
  • Patent number: 10709752
    Abstract: This invention relates to a pharmaceutical composition and a health functional food for preventing or improving neurodegenerative disorders comprising mixed herb extracts of Dioscorea Rhizoma and Dioscorea nipponica in a weight ratio of 3.5:1 (w/w). The herb extracts mixed Dioscorea Rhizoma and Dioscorea nipponica in a weight ratio of 3.5:1 have the synergetic effects on increasing the amount of nerve growth factor in vivo, increasing the neural cell proliferation, promoting the formation of neuritis and enhancing cognitive abilities. Thus, the herb extracts of the present invention may be used for a pharmaceutical composition and a health functional food for preventing or treating neurodegenerative disorders.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: July 14, 2020
    Assignee: DONG-A ST CO., LTD.
    Inventors: Soon-Hoe Kim, Mi-Won Son, Sang-Zin Choi, Hye-Ju Kim, Ja-Young Ryu, Sun-Yeou Kim
  • Patent number: 10660928
    Abstract: The present invention relates to a pharmaceutical composition for treating and preventing degenerative neurological disorders, containing, as an active ingredient, a mixture extract of two or more types selected from the group consisting of Moutan Root Bark, Angelica Dahurica Root, and Bupleurum Root, or a fraction thereof.
    Type: Grant
    Filed: March 8, 2017
    Date of Patent: May 26, 2020
    Assignees: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY, DONG-A ST CO., LTD.
    Inventors: Youngmi Kim, Myung Sook Oh, Seon-Pyo Hong, Mi Won Sohn, Jin Seok Jeong, Hai Hua Jiang, Eunjin Kim, Ja Young Ryu, Young Woong Cho, Xiao Fei Du, Sang Zin Choi, Jeong Soo Kim, Byoung Moon Kim
  • Patent number: 10588927
    Abstract: The present invention relates to a composition comprising the mixed extract of mulberry and Poria cocos peel for preventing, improving or treating neurodegenerative disorders. The mixed extract of mulberry and Poria cocos peel which is the active ingredients contained in the composition of the present invention, has a memory improving activity through inhibiting of acetylcholine esterase and a neuroprotective effects and neuron protection by inhibiting the formation of beta amyloid and tau phosphorylation and promoting NGF production. Thus, the present invention may be useful as a pharmaceutical composition for preventing or treating degenerative neurological diseases, or as a health food for the above purpose.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: March 17, 2020
    Assignee: NeuroBo Pharmaceuticals, Inc.
    Inventors: Sang Zin Choi, Mi Won Sohn, Hyo Sang Go, Ja Young Ryu, Jin Seok Jeong, Song Hyen Choi, Eun Jin Kim, Young Woong Cho, So Young Kim
  • Publication number: 20200009210
    Abstract: The present invention relates to a pharmaceutical composition comprising an Indigo Pulverata Levis extract or a fraction thereof as an effective ingredient for preventing or treating inflammatory bowel disease. Exhibiting the effect of reducing the activity and expression of inflammatory activation markers and alleviating the disease activity index of inflammatory bowel disease, an Indigo Pulverata Levis extract or a fraction thereof according to the present invention may be useful as an agent for preventing and treating inflammatory bowel disease.
    Type: Application
    Filed: December 20, 2017
    Publication date: January 9, 2020
    Inventors: Young Woong Cho, Mi Won Son, Sang Zin Choi, Song Hyen Choi, Jin Seok Jeong, In Sung Song, Nayoung Kim
  • Patent number: 10398747
    Abstract: Disclosed are a pharmaceutical composition and a health functional food for the prevention and treatment of diabetic peripheral neuropathy, comprising an herb extract of a mixture of 3.5:1 Dioscorea Rhizoma:Dioscorea nipponica (w/w). Having the ability to synergistically increase in vivo levels of nerve growth factor, compared to the extracts from the herbs alone or her mixtures of other weight ratios, the mixed herb extract is effective for preventing the apoptosis of nerve cells and promoting nerve regeneration. Thus, it can be applied to pharmaceutical compositions and health function foods preventive and curative of diabetic peripheral neuropathy.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: September 3, 2019
    Assignee: Dong-A St Co., Ltd.
    Inventors: Soon-Hoe Kim, Mi-Won Son, Sang-Zin Choi, Hye-Ju Kim, Ja-Young Ryu, Sun-Yeou Kim
  • Publication number: 20180318377
    Abstract: Disclosed are a pharmaceutical composition and a health functional food for the prevention and treatment of diabetic peripheral neuropathy, comprising an herb extract of a mixture of 3.5:1 Dioscorea Rhizoma:Dioscorea nipponica (w/w). Having the ability to synergistically increase in vivo levels of nerve growth factor, compared to the extracts from the herbs alone or her mixtures of other weight ratios, the mixed herb extract is effective for preventing the apoptosis of nerve cells and promoting nerve regeneration. Thus, it can be applied to pharmaceutical compositions and health function foods preventive and curative of diabetic peripheral neuropathy.
    Type: Application
    Filed: July 12, 2018
    Publication date: November 8, 2018
    Inventors: Soon-Hoe KIM, Mi-Won SON, Sang-Zin CHOI, Hye-Ju KIM, Ja-Young RYU, Sun-Yeou KIM
  • Publication number: 20180256658
    Abstract: The present invention relates to a composition comprising the mixed extract of mulberry and Poria cocos peel for preventing, improving or treating neurodegenerative disorders. The mixed extract of mulberry and Poria cocos peel which is the active ingredients contained in the composition of the present invention, has a memory improving activity through inhibiting of acetylcholine esterase and a neuroprotective effects and neuron protection by inhibiting the formation of beta amyloid and tau phosphorylation and promoting NGF production. Thus, the present invention may be useful as a pharmaceutical composition for preventing or treating degenerative neurological diseases, or as a health food for the above purpose.
    Type: Application
    Filed: December 3, 2015
    Publication date: September 13, 2018
    Inventors: Sang Zin CHOI, Mi Won SOHN, Hyo Sang GO, Ja Young RYU, Jin Seok JEONG, Song Hyen CHOI, Eun Jin KIM, Young Woong CHO, So Young KIM
  • Publication number: 20170368122
    Abstract: The present invention relates to a pharmaceutical composition and a food composition for preventing or ameliorating degenerative neurological disease comprising Poria cocos peel extract for preventing, or treating neurodegenerative disorders. Poria cocos peel extract which is the active ingredients contained in the composition of the present invention, has a memory ameliorating activity through inhibiting of acetylcholine esterase and a neuroprotective effect and neuron protection by inhibiting the formation of beta amyloid and tau phosphorylation and promoting NGF production. Thus, the present invention may be useful as a pharmaceutical composition for preventing or treating degenerative neurological diseases, or as a health food for the above purpose.
    Type: Application
    Filed: December 3, 2015
    Publication date: December 28, 2017
    Inventors: Sang Zin CHOI, Mi Won SOHN, Hyo Sang GO, Ja Young RYU, Jin Seok JEONG, Song Hyen CHOI, Eun Jin KIM, Young Woong CHO, So Young KIM
  • Publication number: 20170224754
    Abstract: The present invention relates to a pharmaceutical composition for treating and preventing degenerative neurological disorders, containing, as an active ingredient, a mixture extract of two or more types selected from the group consisting of Moutan Root Bark, Angelica Dahurica Root, and Bupleurum Root, or a fraction thereof.
    Type: Application
    Filed: March 8, 2017
    Publication date: August 10, 2017
    Applicants: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY, DONG-A ST CO., LTD.
    Inventors: Youngmi KIM, Myung Sook OH, Seon-Pyo HONG, Mi Won SOHN, Jin Seok JEONG, Hai Hua JIANG, Eunjin KIM, Ja Young RYU, Young Woong CHO, Xiao Fei DU, Sang Zin CHOI, Jeong Soo KIM, Byoung Moon KIM
  • Publication number: 20170216390
    Abstract: This invention relates to a pharmaceutical composition and a health functional food for preventing or improving neurodegenerative disorders comprising mixed herb extracts of Dioscorea Rhizoma and Dioscorea nipponica in a weight ratio of 3.5:1 (w/w). The herb extracts mixed Dioscorea Rhizoma and Dioscorea nipponica in a weight ratio of 3.5:1 have the synergetic effects on increasing the amount of nerve growth factor in vivo, increasing the neural cell proliferation, promoting the formation of neuritis and enhancing cognitive abilities. Thus, the herb extracts of the present invention may be used for a pharmaceutical composition and a health functional food for preventing or treating neurodegenerative disorders.
    Type: Application
    Filed: April 10, 2017
    Publication date: August 3, 2017
    Inventors: Soon-Hoe KIM, Mi-Won SON, Sang-Zin CHOI, Hye-Ju KIM, Ja-Young RYU, Sun-Yeou KIM
  • Publication number: 20170209515
    Abstract: Disclosed are a pharmaceutical composition and a health functional food for the prevention and treatment of diabetic peripheral neuropathy, comprising an herb extract of a mixture of 3.5:1 Dioscorea Rhizoma:Dioscorea nipponica (w/w). Having the ability to synergistically increase in vivo levels of nerve growth factor, compared to the extracts from the herbs alone or herb mixtures of other weight ratios, the mixed herb extract is effective for preventing the apoptosis of nerve cells and promoting nerve regeneration. Thus, it can be applied to pharmaceutical compositions and health functional foods preventive and curative of diabetic peripheral neuropathy.
    Type: Application
    Filed: April 10, 2017
    Publication date: July 27, 2017
    Inventors: Soon-Hoe KIM, Mi-Won SON, Sang-Zin CHOI, Hye-Ju KIM, Ja-Young RYU, Sun-Yeou KIM
  • Publication number: 20140155609
    Abstract: The present invention relates to a novel quinoline derivative compound, an optical isomer thereof, a pharmaceutically acceptable salt thereof, and a hydrate or a solvate thereof. The novel quinoline derivative compound, the optical isomer thereof, the pharmaceutically acceptable salt thereof, and the hydrate or the solvate thereof accelerates gastrointestinal movement, and thus can effectively prevent or treat gastrointestinal motility disorders.
    Type: Application
    Filed: November 24, 2010
    Publication date: June 5, 2014
    Applicant: Dong-A ST Co., Ltd.
    Inventors: Miwon Son, Tae Ho Lee, Sang Zin Choi, Nam Joon Baek, Kang Ro Lee, Ki Hyun Kim, Soon Hoe Kim